neratinib
Neratinib is used as an adjuvant therapy in people with early stage breast cancer in which HER2 is overexpressed, after the person receives treatment with trastuzumab. It is a tyrosine kinase inhibitor anticancer drug. Reference standards of Neratinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Neratinib
[catalogue_number] => PA 14 74000
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[chemical_name] =>
[weight] => 557.04
[form] => C30H29ClN6O3
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Catalogue No.:PA 14 74000
Molecular Formula : C30H29ClN6O3
Molecular Weight : 557.04
stdClass Object
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[pname] => Neratinib-d6
[catalogue_number] => PA STI 067320
[category_ids] => ,79,80,71,98,78,70,82,
[chemical_name] =>
[weight] => 563.08
[form] => C30H23D6ClN6O3
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Catalogue No.:PA STI 067320
Molecular Formula : C30H23D6ClN6O3
Molecular Weight : 563.08
stdClass Object
(
[pname] => (E)-4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline-3-carboxylic Acid
[catalogue_number] => PA 14 74520
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 576.05
[form] => C30H30ClN5O5
[cas] => NA
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(E)-4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline-3-carboxylic Acid
Catalogue No.:PA 14 74520
Molecular Formula : C30H30ClN5O5
Molecular Weight : 576.05
stdClass Object
(
[pname] => N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)acetamide
[catalogue_number] => PA 14 74530
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[weight] => 473.92
[form] => C25H20ClN5O3
[cas] => 2748212-19-1
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N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)acetamide
Catalogue No.:PA 14 74530
Molecular Formula : C25H20ClN5O3
Molecular Weight : 473.92
stdClass Object
(
[pname] => (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(methylamino)but-2-enamide
[catalogue_number] => PA 14 74540
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[weight] => 543.02
[form] => C29H27ClN6O3
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(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(methylamino)but-2-enamide
Catalogue No.:PA 14 74540
Molecular Formula : C29H27ClN6O3
Molecular Weight : 543.02
stdClass Object
(
[pname] => (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
[catalogue_number] => PA 14 74550
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[weight] => 543.02
[form] => C29H27ClN6O3
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(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
Catalogue No.:PA 14 74550
Molecular Formula : C29H27ClN6O3
Molecular Weight : 543.02
stdClass Object
(
[pname] => (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-hydroxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
[catalogue_number] => PA 14 74560
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[chemical_name] =>
[weight] => 529
[form] => C28H25ClN6O3
[cas] => NA
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(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-hydroxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
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[catalogue_number] => PA 14 74570
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[weight] => 465.94
[form] => C24H24ClN5O3
[cas] => 1895881-83-0
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(E)-N-(4-((3-Chloro-4-hydroxyphenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
Catalogue No.:PA 14 74570
Molecular Formula : C24H24ClN5O3
Molecular Weight : 465.94
stdClass Object
(
[pname] => (Z)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
[catalogue_number] => PA 14 0741000
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[chemical_name] =>
[weight] => 557.05
[form] => C30H29ClN6O3
[cas] => 2186660-79-5
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(Z)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
Catalogue No.:PA 14 0741000
Molecular Formula : C30H29ClN6O3
Molecular Weight : 557.05
stdClass Object
(
[pname] => N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide
[catalogue_number] => PA 14 0741001
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[weight] => 473.92
[form] => C25H20ClN5O3
[cas] => 1144516-20-0
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N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide
Catalogue No.:PA 14 0741001
Molecular Formula : C25H20ClN5O3
Molecular Weight : 473.92
stdClass Object
(
[pname] => 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
[catalogue_number] => PA 14 0741002
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[chemical_name] =>
[weight] => 445.91
[form] => C24H20ClN5O2
[cas] => 848139-78-6
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6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
Catalogue No.:PA 14 0741002
Molecular Formula : C24H20ClN5O2
Molecular Weight : 445.91
stdClass Object
(
[pname] => Neratinib pyridine N-oxide (M3)
[catalogue_number] => PA 14 0741003
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 573.05
[form] => C30H29ClN6O4
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Neratinib pyridine N-oxide (M3)
Catalogue No.:PA 14 0741003
Molecular Formula : C30H29ClN6O4
Molecular Weight : 573.05
stdClass Object
(
[pname] => Neratinib dimethylamine N-oxide (M7)
[catalogue_number] => PA 14 0741004
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[weight] => 573.05
[form] => C30H29ClN6O4
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Neratinib dimethylamine N-oxide (M7)
Catalogue No.:PA 14 0741004
Molecular Formula : C30H29ClN6O4
Molecular Weight : 573.05
stdClass Object
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[catalogue_number] => PA 14 0741005
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[chemical_name] =>
[weight] => 487.94
[form] => C26H22ClN5O3
[cas] => 915941-95-6
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N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)acetamide
Catalogue No.:PA 14 0741005
Molecular Formula : C26H22ClN5O3
Molecular Weight : 487.94
stdClass Object
(
[pname] => N-Nitroso Neratinib
[catalogue_number] => PA 14 0741006
[category_ids] => ,79,80,71,81,78,70,82,
[chemical_name] =>
[weight] => 586.05
[form] => C30H28ClN7O4
[cas] => NA
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Catalogue No.:PA 14 0741006
Molecular Formula : C30H28ClN7O4
Molecular Weight : 586.05
stdClass Object
(
[pname] => Neratinib Bis-N-Oxide (M11)
[catalogue_number] => PA 14 0741007
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[chemical_name] =>
[weight] => 589.05
[form] => C30H29ClN6O5
[cas] => NA
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Neratinib Bis-N-Oxide (M11)
Catalogue No.:PA 14 0741007
Molecular Formula : C30H29ClN6O5
Molecular Weight : 589.05
stdClass Object
(
[pname] => Neratinib Quinoline N-Oxide
[catalogue_number] => PA 14 0741008
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[weight] => 573.05
[form] => C30H29ClN6O4
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Neratinib Quinoline N-Oxide
Catalogue No.:PA 14 0741008
Molecular Formula : C30H29ClN6O4
Molecular Weight : 573.05