Remibrutinib
Intermediates
- Remibrutinib is an oral Bruton's tyrosine kinase (BTK) inhibitor developed for the treatment of chronic spontaneous urticaria and other immune-mediated inflammatory conditions. Reference standards of Remibrutinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Remibrutinib
[catalogue_number] => PA 18 1820000
[category_ids] => ,70,78,82,93,
[chemical_name] =>
[weight] => 507.54
[form] => C27H27F2N5O3
[cas] => 1787294-07-8
[pslug] => 1787294-07-8-remibrutinib-pa181820000
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Catalogue No.:PA 18 1820000
Molecular Formula : C27H27F2N5O3
Molecular Weight : 507.54
stdClass Object
(
[pname] => N-(3-(6-Amino-5-(2-(methyl(nitroso)amino)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
[catalogue_number] => PA 18 1821000
[category_ids] => ,70,78,82,93,162,
[chemical_name] =>
[weight] => 482.49
[form] => C24H24F2N6O3
[cas] => 3103121-14-5
[pslug] => 3103121-14-5-n-3-6-amino-5-2-methyl-nitroso-amino-ethoxy-pyrimidin-4-yl-5-fluoro-2-methylphenyl-4-cyclopropyl-2-fluorobenzamide-pa181821000
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N-(3-(6-Amino-5-(2-(methyl(nitroso)amino)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
Catalogue No.:PA 18 1821000
Molecular Formula : C24H24F2N6O3
Molecular Weight : 482.49
stdClass Object
(
[pname] => N-(2-((4-Amino-6-chloropyrimidin-5-yl)oxy)ethyl)-N-methylnitrous amide
[catalogue_number] => PA 18 1821001
[category_ids] => ,70,78,82,93,162,
[chemical_name] =>
[weight] => 231.64
[form] => C7H10ClN5O2
[cas] => NA
[pslug] => n-2-4-amino-6-chloropyrimidin-5-yl-oxy-ethyl-n-methylnitrous-amide-pa181821001
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N-(2-((4-Amino-6-chloropyrimidin-5-yl)oxy)ethyl)-N-methylnitrous amide
Catalogue No.:PA 18 1821001
Molecular Formula : C7H10ClN5O2
Molecular Weight : 231.64
stdClass Object
(
[pname] => 4-Cyclopropyl-2-fluorobenzonitrile
[catalogue_number] => PA 18 1821002
[category_ids] => ,70,78,82,93,
[chemical_name] =>
[weight] => 161.18
[form] => C10H8FN
[cas] => 1394068-31-5
[pslug] => 1394068-31-5-4-cyclopropyl-2-fluorobenzonitrile-pa181821002
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4-Cyclopropyl-2-fluorobenzonitrile
Catalogue No.:PA 18 1821002
Molecular Formula : C10H8FN
Molecular Weight : 161.18
stdClass Object
(
[pname] => 4-Cyclopropyl-2-fluorobenzoic Acid
[catalogue_number] => PA 18 1821003
[category_ids] => ,70,78,82,93,
[chemical_name] =>
[weight] => 180.18
[form] => C10H9FO2
[cas] => 1247927-81-6
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4-Cyclopropyl-2-fluorobenzoic Acid
Catalogue No.:PA 18 1821003
Molecular Formula : C10H9FO2
Molecular Weight : 180.18
