tofacitinib citrate
A janus kinase (JAK) inhibitor class of drug used for the treatment of rheumatoid arthritis (RA)Reference standards of Tofacitinib Citrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Tofacitinib Citrate
[catalogue_number] => PA 47 13000
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[weight] => 504.49
[form] => C22H28N6O8
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Catalogue No.:PA 47 13000
Molecular Formula : C22H28N6O8
Molecular Weight : 504.49
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[pname] => N,4-Dimethyl-1-benzyl-3-piperidinamine
[catalogue_number] => PA 47 13570
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[chemical_name] =>
[weight] => 218.34
[form] => C14H22N2
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N,4-Dimethyl-1-benzyl-3-piperidinamine
Catalogue No.:PA 47 13570
Molecular Formula : C14H22N2
Molecular Weight : 218.34
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[catalogue_number] => PA 47 13580
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[chemical_name] =>
[weight] => 291.26
[form] => C14H24Cl2N2
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(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13580
Molecular Formula : C14H24Cl2N2
Molecular Weight : 291.26
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(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13590
Molecular Formula : C14H24Cl2N2
Molecular Weight : 291.26
stdClass Object
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3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanamide
Catalogue No.:PA 47 13610
Molecular Formula : C16H22N6O2
Molecular Weight : 330.38
stdClass Object
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N-Methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13630
Molecular Formula : C13H19N5
Molecular Weight : 245.32
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Des-(N-oxopropanenitrile)-N-methylbenzyl
Catalogue No.:PA 47 13640
Molecular Formula : C20H25N5
Molecular Weight : 335.45
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N-((3S,4S)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Catalogue No.:PA 47 13650
Molecular Formula : C20H25N5
Molecular Weight : 335.45
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[form] => C16H20N6O
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3-(4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13660
Molecular Formula : C16H20N6O
Molecular Weight : 312.37
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Catalogue No.:PA 47 13670
Molecular Formula : C6H4ClN3
Molecular Weight : 153.57
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4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13680
Molecular Formula : C13H10ClN3O2S
Molecular Weight : 307.76
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[weight] => 349.47
[form] => C21H27N5
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Catalogue No.:PA 47 13690
Molecular Formula : C21H27N5
Molecular Weight : 349.47
stdClass Object
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1-((3R,4R)-4-Methyl-3-(methyl(1H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
Catalogue No.:PA 47 13710
Molecular Formula : C15H21N5O
Molecular Weight : 287.37
stdClass Object
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[weight] => 506.52
[form] => C22H30N6O8
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3-((3R,4R)-3-((6,7-Dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
Catalogue No.:PA 47 13740
Molecular Formula : C22H30N6O8
Molecular Weight : 506.52
stdClass Object
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[catalogue_number] => PA 47 13780
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[weight] => 346.39
[form] => C16H22N6O3
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3-((3R,4R)-3-(((5S,6R)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13780
Molecular Formula : C16H22N6O3
Molecular Weight : 346.39
stdClass Object
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3-((3R,4R)-3-(((5R,6S)-5,6-Dihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13790
Molecular Formula : C16H22N6O3
Molecular Weight : 346.39
stdClass Object
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3-((3R,4R)-4-Methyl-3-(methyl((5R,6S)-2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13800
Molecular Formula : C16H22N6O4
Molecular Weight : 362.39
stdClass Object
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3-((3R,4R)-4-Methyl-3-(methyl((5S,6R)-2,5,6-trihydroxy-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13810
Molecular Formula : C16H22N6O4
Molecular Weight : 362.39
stdClass Object
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[catalogue_number] => PA 47 13820
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[weight] => 328.38
[form] => C16H20N6O2
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3-((3R,4R)-4-Methyl-3-(methyl(5-oxo-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 13820
Molecular Formula : C16H20N6O2
Molecular Weight : 328.38
stdClass Object
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[catalogue_number] => PA 47 13840
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[weight] => 623.77
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3-Imino-5-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)-2-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carbonyl)-5-oxopentanenitrile
Catalogue No.:PA 47 13840
Molecular Formula : C33H41N11O2
Molecular Weight : 623.77
stdClass Object
(
[pname] => (3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
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[weight] => 261.33
[form] => C13H19N5O
[cas] => NA
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(3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine 1-Oxide
Catalogue No.:PA 47 13860
Molecular Formula : C13H19N5O
Molecular Weight : 261.33
stdClass Object
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[catalogue_number] => PA 47 13870
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[weight] => 153.57
[form] => C6H4ClN3
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2-Chloro-1H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13870
Molecular Formula : C6H4ClN3
Molecular Weight : 153.57
stdClass Object
(
[pname] => 2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine
[catalogue_number] => PA 47 13880
[category_ids] => ,85,83,70,
[chemical_name] =>
[weight] => 188.01
[form] => C6H3Cl2N3
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2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 13880
Molecular Formula : C6H3Cl2N3
Molecular Weight : 188.01
stdClass Object
(
[pname] => (3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
[catalogue_number] => PA 47 13890
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[chemical_name] =>
[weight] => 291.26
[form] => C14H24Cl2N2
[cas] => 1354486-07-9
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(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine Dihydrochloride
Catalogue No.:PA 47 13890
Molecular Formula : C14H24Cl2N2
Molecular Weight : 291.26
stdClass Object
(
[pname] => Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
[catalogue_number] => PA 47 0131002
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[weight] => 387.48
[form] => C20H29N5O3
[cas] => 2227199-31-5
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Butyl 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoate
Catalogue No.:PA 47 0131002
Molecular Formula : C20H29N5O3
Molecular Weight : 387.48
stdClass Object
(
[pname] => 3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile
[catalogue_number] => PA 47 0131003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 379.42
[form] => C19H21N7O2
[cas] => 2459302-77-1
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3-(4-(((3R,4R)-1-(2-Cyanoacetyl)-4-methylpiperidin-3-yl)(methyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-oxopropanenitrile
Catalogue No.:PA 47 0131003
Molecular Formula : C19H21N7O2
Molecular Weight : 379.42
stdClass Object
(
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[catalogue_number] => PA 47 0131004
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[chemical_name] =>
[weight] => 270.68
[form] => C12H7ClN6
[cas] => 134965-85-8
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4'-Chloro-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine
Catalogue No.:PA 47 0131004
Molecular Formula : C12H7ClN6
Molecular Weight : 270.68
stdClass Object
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[weight] => 287.37
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1-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one
Catalogue No.:PA 47 0131005
Molecular Formula : C15H21N5O
Molecular Weight : 287.37
stdClass Object
(
[pname] => Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate
[catalogue_number] => PAI 47 013001
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[weight] => 427.51
[form] => C21H29N7O3
[cas] => NA
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Ethyl 4-cyano-5-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-imino-5-oxopentanoate
Catalogue No.:PAI 47 013001
Molecular Formula : C21H29N7O3
Molecular Weight : 427.51
stdClass Object
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[pname] => Tofacitinib Citrate (IPRST025)
[catalogue_number] => PA IPRST025
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Tofacitinib Citrate (IPRST025)
stdClass Object
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[pname] => 4-Cyano-2-hydroxy-5-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentane-1,2,3-tricarboxylic Acid
[catalogue_number] => PA 47 0131007
[category_ids] => ,82,80,79,78,70,
[chemical_name] =>
[weight] => 502.48
[form] => C22H26N6O8
[cas] => NA
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4-Cyano-2-hydroxy-5-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-5-oxopentane-1,2,3-tricarboxylic Acid
Catalogue No.:PA 47 0131007
Molecular Formula : C22H26N6O8
Molecular Weight : 502.48
stdClass Object
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[catalogue_number] => PA 47 0131008
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[weight] => 218.34
[form] => C14H22N2
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(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine
Catalogue No.:PA 47 0131008
Molecular Formula : C14H22N2
Molecular Weight : 218.34
stdClass Object
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[catalogue_number] => PA 47 0131009
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[weight] => 204.32
[form] => C13H20N2
[cas] => 1039738-27-6
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1-Benzyl-4-methylpiperidin-3-amine
Catalogue No.:PA 47 0131009
Molecular Formula : C13H20N2
Molecular Weight : 204.32
stdClass Object
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[weight] => 204.32
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rel-(3R,4R)-1-Benzyl-4-methylpiperidin-3-amine
Catalogue No.:PA 47 0131010
Molecular Formula : C13H20N2
Molecular Weight : 204.32
stdClass Object
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[catalogue_number] => PA 47 0131011
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[weight] => 232.37
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1-Benzyl-N-ethyl-4-methylpiperidin-3-amine
Catalogue No.:PA 47 0131011
Molecular Formula : C15H24N2
Molecular Weight : 232.37
stdClass Object
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[catalogue_number] => PA 47 0131012
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[weight] => 232.37
[form] => C15H24N2
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(3R,4R)-1-Benzyl-N-ethyl-4-methylpiperidin-3-amine
Catalogue No.:PA 47 0131012
Molecular Formula : C15H24N2
Molecular Weight : 232.37