bendamustine hydrochloride

Metabolites - An alkylating agent with chemical formula 1Hbenzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1 methyl-, monohydrochloride. It contains a mechlorethamine group and a benzimidazole heterocyclic ring with a butyric acid substituent. It is used for the treatment of chronic lymphocytic leukemia and lymphomas. Reference standards of Bendamustine Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Bendamustine Hydrochloride
    [catalogue_number] => PA 02 07000
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 394.72
    [form] => C16H22Cl3N3O2
    [cas] => 3543-75-7
    [pslug] => 3543-75-7-bendamustine-hydrochloride-api-pa0207000
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PA 02 07000
PA 02 07000

Bendamustine Hydrochloride

  • Catalogue No.:PA 02 07000

  • CAS :

    3543-75-7

  • Molecular Formula : C16H22Cl3N3O2

  • Molecular Weight : 394.72

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stdClass Object
(
    [pname] => 4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07610
    [category_ids] => ,70,71,75,76,78,80,82,
    [chemical_name] => 
    [weight] => 353.87
    [form] => C16H20ClN3O2S
    [cas] => 191939-34-1
    [pslug] => 191939-34-1-4-6-2-chloroethyl-3-methyl-3-6-7-8-tetrahydroimidazo-4-5-5-6-benzo-1-2-b-1-4-thiazin-2-yl-butanoic-acid-pa0207610
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PA 02 07610
PA 02 07610

4-(6-(2-Chloroethyl)-3-methyl-3,6,7,8-tetrahydroimidazo[4',5':5,6]benzo[1,2-b][1,4]thiazin-2-yl)butanoic Acid

  • Catalogue No.:PA 02 07610

  • CAS :

    191939-34-1

  • Molecular Formula : C16H20ClN3O2S

  • Molecular Weight : 353.87

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stdClass Object
(
    [pname] => Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate
    [catalogue_number] => PA 02 07620
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 305.33
    [form] => C15H19N3O4
    [cas] => 1374784-01-6
    [pslug] => 1374784-01-6-isopropyl-4-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-butanoate-pa0207620
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PA 02 07620
PA 02 07620

Isopropyl 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)Butanoate

  • Catalogue No.:PA 02 07620

  • CAS :

    1374784-01-6

  • Molecular Formula : C15H19N3O4

  • Molecular Weight : 305.33

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stdClass Object
(
    [pname] => 1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane
    [catalogue_number] => PA 02 07630
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 394.38
    [form] => C19H18N6O4
    [cas] => 914626-65-6
    [pslug] => 914626-65-6-1-3-bis-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-propane-pa0207630
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PA 02 07630
PA 02 07630

1,3-Bis(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)propane

  • Catalogue No.:PA 02 07630

  • CAS :

    914626-65-6

  • Molecular Formula : C19H18N6O4

  • Molecular Weight : 394.38

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stdClass Object
(
    [pname] => N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide
    [catalogue_number] => PA 02 07640
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 430.41
    [form] => C19H22N6O6
    [cas] => NA
    [pslug] => n1-n5-bis-2-methylamino-5-nitrophenyl-glutaramide-pa0207640
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PA 02 07640
PA 02 07640

N1,N5-Bis(2-(methylamino)-5-nitrophenyl)glutaramide

  • Catalogue No.:PA 02 07640

  • CAS :

    NA

  • Molecular Formula : C19H22N6O6

  • Molecular Weight : 430.41

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stdClass Object
(
    [pname] => 2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)
    [catalogue_number] => PA 02 07650
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 334.42
    [form] => C19H22N6
    [cas] => 847588-86-7
    [pslug] => 847588-86-7-2-2-propane-1-3-diyl-bis-1-methyl-1h-benzo-d-imidazol-5-amine-pa0207650
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PA 02 07650
PA 02 07650

2,2'-(Propane-1,3-diyl)bis(1-methyl-1H-benzo[d]imidazol-5-amine)

  • Catalogue No.:PA 02 07650

  • CAS :

    847588-86-7

  • Molecular Formula : C19H22N6

  • Molecular Weight : 334.42

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stdClass Object
(
    [pname] => 2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate
    [catalogue_number] => PA 02 07660
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 432.34
    [form] => C19H27Cl2N3O4
    [cas] => NA
    [pslug] => 2-3-dihydroxypropyl-4-5-bis-2-chloroethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoate-pa0207660
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PA 02 07660
PA 02 07660

2,3-Dihydroxypropyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

  • Catalogue No.:PA 02 07660

  • CAS :

    NA

  • Molecular Formula : C19H27Cl2N3O4

  • Molecular Weight : 432.34

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stdClass Object
(
    [pname] => 4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid
    [catalogue_number] => PA 02 07670
    [category_ids] => ,80,71,76,75,
    [chemical_name] => 
    [weight] => 381.85
    [form] => C18H24ClN3O4
    [cas] => NA
    [pslug] => 4-5-2-acetoxyethyl-2-chloroethyl-amino-1-methyl-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa0207670
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PA 02 07670
PA 02 07670

4-(5-((2-Acetoxyethyl)(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid

  • Catalogue No.:PA 02 07670

  • CAS :

    NA

  • Molecular Formula : C18H24ClN3O4

  • Molecular Weight : 381.85

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stdClass Object
(
    [pname] => Bendamustine Monohydroxy Acid Hydrochloride
    [catalogue_number] => PA 02 0071000
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 376.28
    [form] => C16H23Cl2N3O3
    [cas] => 109882-26-0
    [pslug] => 109882-26-0-bendamustine-monohydroxy-acid-hydrochloride-pa020071000
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PA 02 0071000
PA 02 0071000

Bendamustine Monohydroxy Acid Hydrochloride

  • Catalogue No.:PA 02 0071000

  • CAS :

    109882-26-0

  • Molecular Formula : C16H23Cl2N3O3

  • Molecular Weight : 376.28

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stdClass Object
(
    [pname] => 4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid
    [catalogue_number] => PA 02 0071001
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 263.25
    [form] => C12H13N3O4
    [cas] => 31349-48-1
    [pslug] => 31349-48-1-4-1-methyl-5-nitro-1h-benzo-d-imidazol-2-yl-butanoic-acid-pa020071001
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PA 02 0071001
PA 02 0071001

4-(1-Methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoic Acid

  • Catalogue No.:PA 02 0071001

  • CAS :

    31349-48-1

  • Molecular Formula : C12H13N3O4

  • Molecular Weight : 263.25

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stdClass Object
(
    [pname] => N-Methyl-2,4-dinitroaniline
    [catalogue_number] => PA 02 0071002
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 197.15
    [form] => C7H7N3O4
    [cas] => 2044-88-4
    [pslug] => 2044-88-4-n-methyl-2-4-dinitroaniline-pa020071002
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PA 02 0071002
PA 02 0071002

N-Methyl-2,4-dinitroaniline

  • Catalogue No.:PA 02 0071002

  • CAS :

    2044-88-4

  • Molecular Formula : C7H7N3O4

  • Molecular Weight : 197.15

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stdClass Object
(
    [pname] => Bendamustine Ether Impurity
    [catalogue_number] => PA 02 0071003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 303.36
    [form] => C16H21N3O3
    [cas] => 1228552-02-0
    [pslug] => 1228552-02-0-bendamustine-ether-impurity-pa020071003
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PA 02 0071003
PA 02 0071003

Bendamustine Ether Impurity

  • Catalogue No.:PA 02 0071003

  • CAS :

    1228552-02-0

  • Molecular Formula : C16H21N3O3

  • Molecular Weight : 303.36

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stdClass Object
(
    [pname] => Bendamustine Dideschloroethyl Acid Hydrochloride
    [catalogue_number] => PA 02 0071004
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 269.73
    [form] => C12H16ClN3O2
    [cas] => 1179363-38-2
    [pslug] => 1179363-38-2-bendamustine-dideschloroethyl-acid-hydrochloride-pa020071004
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PA 02 0071004
PA 02 0071004

Bendamustine Dideschloroethyl Acid Hydrochloride

  • Catalogue No.:PA 02 0071004

  • CAS :

    1179363-38-2

  • Molecular Formula : C12H16ClN3O2

  • Molecular Weight : 269.73

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