erlotinib
Metabolites
- An orally active tyrosine kinase inhibitor, Erlotinib is an anti cancer drug. It acts on the epidermal growth factor receptor (EGFR) and it is used for the treatment of several types of cancer like lung cancer, pancreatic cancer etc. Reference standards of Erlotinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Erlotinib O-Desmethyl Metabolite (M14)
[catalogue_number] => PA 05 14510
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[weight] => 379.41
[form] => C21H21N3O4
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Erlotinib O-Desmethyl Metabolite (M14)
Catalogue No.:PA 05 14510
Molecular Formula : C21H21N3O4
Molecular Weight : 379.41
stdClass Object
(
[pname] => Didesmethyl Erlotinib Hydrochloride Salt
[catalogue_number] => PA 05 14530
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[chemical_name] =>
[weight] => 401.84
[form] => C20H20ClN3O4
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Didesmethyl Erlotinib Hydrochloride Salt
Catalogue No.:PA 05 14530
Molecular Formula : C20H20ClN3O4
Molecular Weight : 401.84
stdClass Object
(
[pname] => OSI-420-d4
[catalogue_number] => PA STI 070430
[category_ids] => ,80,71,98,76,75,78,70,82,
[chemical_name] =>
[weight] => 383.43
[form] => C21H17D4N3O4
[cas] => 1216420-11-9
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Catalogue No.:PA STI 070430
Molecular Formula : C21H17D4N3O4
Molecular Weight : 383.43
stdClass Object
(
[pname] => 4-Hydroxy Erlotinib Hydrochloride
[catalogue_number] => PA 05 50510
[category_ids] => ,76,75,70,78,
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[weight] => 445.9
[form] => C22H24ClN3O5
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4-Hydroxy Erlotinib Hydrochloride
stdClass Object
(
[pname] => N-(2-Methoxyethyl) Erlotinib
[catalogue_number] => PA 05 0141000
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[chemical_name] =>
[weight] => 451.52
[form] => C25H29N3O5
[cas] => 2410548-58-0
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N-(2-Methoxyethyl) Erlotinib
Catalogue No.:PA 05 0141000
Molecular Formula : C25H29N3O5
Molecular Weight : 451.52
stdClass Object
(
[pname] => Ethyl 3,4-bis(2-methoxyethoxy)-2-nitrobenzoate
[catalogue_number] => PA 05 0141001
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[weight] => 343.33
[form] => C15H21NO8
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Ethyl 3,4-bis(2-methoxyethoxy)-2-nitrobenzoate
Catalogue No.:PA 05 0141001
Molecular Formula : C15H21NO8
Molecular Weight : 343.33
stdClass Object
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[catalogue_number] => PA 05 0141002
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[weight] => 349.81
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Ethyl 3-amino-4,5-bis(2-methoxyethoxy)benzoate Hydrochloride
Catalogue No.:PA 05 0141002
Molecular Formula : C15H24ClNO6
Molecular Weight : 349.81
stdClass Object
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[catalogue_number] => PA 05 0141003
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[weight] => 313.35
[form] => C15H23NO6
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Ethyl 2-amino-3,4-bis(2-methoxyethoxy)benzoate
Catalogue No.:PA 05 0141003
Molecular Formula : C15H23NO6
Molecular Weight : 313.35
stdClass Object
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[catalogue_number] => PA 05 0141004
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[weight] => 413.43
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3-((6,7-Bis((methoxymethoxy)methyl)quinazolin-4-yl)amino)benzoic acid
Catalogue No.:PA 05 0141004
Molecular Formula : C21H23N3O6
Molecular Weight : 413.43
stdClass Object
(
[pname] => 2-((6-((6,7-Bis(2-methoxyethoxy)quinazolin-4-yl)(3-ethynylphenyl)amino)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
[catalogue_number] => PA 05 0141005
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[weight] => 717.73
[form] => C34H43N3O14
[cas] => NA
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2-((6-((6,7-Bis(2-methoxyethoxy)quinazolin-4-yl)(3-ethynylphenyl)amino)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalogue No.:PA 05 0141005
Molecular Formula : C34H43N3O14
Molecular Weight : 717.73
stdClass Object
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[pname] => 2-((4-Amino-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-ol
[catalogue_number] => PA 05 0141006
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[weight] => 279.3
[form] => C13H17N3O4
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2-((4-Amino-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-ol
stdClass Object
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[pname] => 4-((3-Ethynylphenyl)amino)-6,7-bis(2-methoxyethoxy)quinazoline 1-oxide
[catalogue_number] => PA 05 0141007
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[chemical_name] =>
[weight] => 409.44
[form] => C22H23N3O5
[cas] => 2596073-36-6
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4-((3-Ethynylphenyl)amino)-6,7-bis(2-methoxyethoxy)quinazoline 1-oxide
Catalogue No.:PA 05 0141007
Molecular Formula : C22H23N3O5
Molecular Weight : 409.44
stdClass Object
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[pname] => 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, 1-oxide
[catalogue_number] => PA 05 0141008
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4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, 1-oxide
Catalogue No.:PA 05 0141008
Molecular Formula : C22H23N3O5
Molecular Weight : 409.44
stdClass Object
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[catalogue_number] => PA 05 0141010
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[weight] => 299.32
[form] => C14H21NO6
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Ethyl 2-amino-4-(2-hydroxyethoxy)-5-(2-methoxyethoxy)benzoate
Catalogue No.:PA 05 0141010
Molecular Formula : C14H21NO6
Molecular Weight : 299.32
stdClass Object
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[catalogue_number] => PA 05 0141011
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[weight] => 299.32
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Ethyl 2-amino-5-(2-hydroxyethoxy)-4-(2-methoxyethoxy)benzoate
Catalogue No.:PA 05 0141011
Molecular Formula : C14H21NO6
Molecular Weight : 299.32
stdClass Object
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[pname] => 4-(3-Aminophenyl)-2-methyl-3-butyn-2-ol
[catalogue_number] => PA 05 0141012
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 175.23
[form] => C11H13NO
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4-(3-Aminophenyl)-2-methyl-3-butyn-2-ol
Catalogue No.:PA 05 0141012
Molecular Formula : C11H13NO
Molecular Weight : 175.23
stdClass Object
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[pname] => 4-(3-Aminophenyl)-2-methylbutan-2-ol
[catalogue_number] => PA 05 0141013
[category_ids] => ,75,76,78,70,82,
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[weight] => 179.26
[form] => C11H17NO
[cas] => 69936-71-6
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4-(3-Aminophenyl)-2-methylbutan-2-ol
Catalogue No.:PA 05 0141013
Molecular Formula : C11H17NO
Molecular Weight : 179.26
stdClass Object
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[catalogue_number] => PA 05 0141014
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[chemical_name] =>
[weight] => 451.52
[form] => C25H29N3O5
[cas] => 299912-60-0
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4-(3-((6,7-Bis(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)-2-methylbut-3-yn-2-ol
Catalogue No.:PA 05 0141014
Molecular Formula : C25H29N3O5
Molecular Weight : 451.52
stdClass Object
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[catalogue_number] => PA 05 0141015
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[weight] => 393.44
[form] => C22H23N3O4
[cas] => 1029721-32-1
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N-(4-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Catalogue No.:PA 05 0141015
Molecular Formula : C22H23N3O4
Molecular Weight : 393.44
stdClass Object
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N-(2-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Catalogue No.:PA 05 0141016
Molecular Formula : C22H23N3O4
Molecular Weight : 393.44
stdClass Object
(
[pname] => 4-(3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)-2-methylbutan-2-ol
[catalogue_number] => PA 05 0141017
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[chemical_name] =>
[weight] => 455.56
[form] => C25H33N3O5
[cas] => NA
[pslug] => 4-3-6-7-bis-2-methoxyethoxy-quinazolin-4-yl-amino-phenyl-2-methylbutan-2-ol-pa050141017
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4-(3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)-2-methylbutan-2-ol
Catalogue No.:PA 05 0141017
Molecular Formula : C25H33N3O5
Molecular Weight : 455.56
stdClass Object
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[catalogue_number] => PA 05 0141019
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[weight] => 343.33
[form] => C15H21NO8
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Ethyl 3,4-bis(2-methoxyethoxy)-5-nitrobenzoate
Catalogue No.:PA 05 0141019
Molecular Formula : C15H21NO8
Molecular Weight : 343.33
stdClass Object
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[catalogue_number] => PA 05 0141021
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Erlotinib 7-O-Desmethyl Metabolite
Catalogue No.:PA 05 0141021
Molecular Formula : C22H21N3O5
Molecular Weight : 407.43
stdClass Object
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[catalogue_number] => PA 05 0141022
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Erlotinib 6-O-Desmethyl Metabolite
Catalogue No.:PA 05 0141022
Molecular Formula : C22H21N3O5
Molecular Weight : 407.43
stdClass Object
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stdClass Object
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[pname] => N-Methoxyethyl Erlotinib Hydrochloride
[catalogue_number] => PA 05 0141024
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[weight] => 487.98
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N-Methoxyethyl Erlotinib Hydrochloride
Catalogue No.:PA 05 0141024
Molecular Formula : C25H30ClN3O5
Molecular Weight : 487.98
stdClass Object
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[catalogue_number] => PA 05 0141025
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[weight] => 347.19
[form] => C14H16Cl2N2O4
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2,4-Dichloro-6,7-bis(2-methoxyethoxy)quinazoline
Catalogue No.:PA 05 0141025
Molecular Formula : C14H16Cl2N2O4
Molecular Weight : 347.19
stdClass Object
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[catalogue_number] => PA 05 0141027
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[weight] => 266.3
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2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile
stdClass Object
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[weight] => 435.48
[form] => C24H25N3O5
[cas] => 2055840-54-3
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N-(6,7-bis(2-methoxyethoxy)quinazolin-4-yl)-N-(3-ethynylphenyl)acetamide
Catalogue No.:PA 05 0141028
Molecular Formula : C24H25N3O5
Molecular Weight : 435.48
stdClass Object
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[catalogue_number] => PA 05 0141029
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[weight] => 369.42
[form] => C20H23N3O4
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Catalogue No.:PA 05 0141029
Molecular Formula : C20H23N3O4
Molecular Weight : 369.42
stdClass Object
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[weight] => 339.39
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(E)-2-(((dimethylamino)methylene)amino)-4,5-bis(2-methoxyethoxy)benzamide
Catalogue No.:PA 05 0141031
Molecular Formula : C16H25N3O5
Molecular Weight : 339.39
stdClass Object
(
[pname] => N-(3-Ethylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
[catalogue_number] => PA 05 0141032
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[weight] => 433.93
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N-(3-Ethylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
Catalogue No.:PA 05 0141032
Molecular Formula : C22H28ClN3O4
Molecular Weight : 433.93
stdClass Object
(
[pname] => 4-((3-Ethynylphenyl)amino)quinazoline-6,7-diol
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[weight] => 277.28
[form] => C16H11N3O2
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4-((3-Ethynylphenyl)amino)quinazoline-6,7-diol
Catalogue No.:PA 05 0141033
Molecular Formula : C16H11N3O2
Molecular Weight : 277.28
stdClass Object
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Catalogue No.:PA 05 0141034
Molecular Formula : C21H23N3O5
Molecular Weight : 397.43
stdClass Object
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[weight] => 429.47
[form] => C22H27N3O6
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4-((6,7-Bis(2-Methoxyethoxy)quinazolin-4-yl)amino)-2-(2-hydroxyethyl)phenol
Catalogue No.:PA 05 0141035
Molecular Formula : C22H27N3O6
Molecular Weight : 429.47
stdClass Object
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[pname] => Erlotinib Acetate
[catalogue_number] => PA 05 0141036
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[weight] => 421.45
[form] => C23H23N3O5
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Catalogue No.:PA 05 0141036
Molecular Formula : C23H23N3O5
Molecular Weight : 421.45
stdClass Object
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[catalogue_number] => PA 05 0141037
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[weight] => 413.43
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Desalkyne Erlotinib benzoic acid
Catalogue No.:PA 05 0141037
Molecular Formula : C21H23N3O6
Molecular Weight : 413.43
stdClass Object
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[pname] => 7-O-Desmethyl Erlotinib Hydrochloride
[catalogue_number] => PA 05 0141038
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[weight] => 415.87
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7-O-Desmethyl Erlotinib Hydrochloride
Catalogue No.:PA 05 0141038
Molecular Formula : C21H22ClN3O4
Molecular Weight : 415.87
stdClass Object
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[pname] => Erlotinib D4
[catalogue_number] => PA STI 088967
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[weight] => 397.47
[form] => C22H19D4N3O4
[cas] => 1130852-41-3
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Catalogue No.:PA STI 088967
Molecular Formula : C22H19D4N3O4
Molecular Weight : 397.47
stdClass Object
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[pname] => Erlotinib D6
[catalogue_number] => PA STI 088968
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[weight] => 399.48
[form] => C22H17D6N3O4
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Catalogue No.:PA STI 088968
Molecular Formula : C22H17D6N3O4
Molecular Weight : 399.48
stdClass Object
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[catalogue_number] => PA 05 0141039
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[weight] => 425.44
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2-(3-((7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-yl)amino)phenyl)acetic acid
Catalogue No.:PA 05 0141039
Molecular Formula : C22H23N3O6
Molecular Weight : 425.44
stdClass Object
(
[pname] => 2-Ethynyl-4-((7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-yl)amino)phenol
[catalogue_number] => PA 05 0141040
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[weight] => 407.43
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2-Ethynyl-4-((7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-yl)amino)phenol
Catalogue No.:PA 05 0141040
Molecular Formula : C22H21N3O5
Molecular Weight : 407.43
stdClass Object
(
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[catalogue_number] => PA 05 0141041
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[weight] => 423.43
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Acetic acid, 2-[2-[[4-[(3-ethynylphenyl)amino]-7-(2-hydroxyethoxy)-6-quinazolinyl]oxy]ethoxy]
Catalogue No.:PA 05 0141041
Molecular Formula : C22H21N3O6
Molecular Weight : 423.43
stdClass Object
(
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[weight] => 409.44
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Ethanol, 2-[[4-[(3-ethynylphenyl)amino]-7-[2-(2-hydroxyethoxy)ethoxy]-6-quinazolinyl]oxy]
Catalogue No.:PA 05 0141042
Molecular Formula : C22H23N3O5
Molecular Weight : 409.44
stdClass Object
(
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[weight] => 365.39
[form] => C20H19N3O4
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4-((3-Ethynylphenyl)amino)-7-(2-(2-hydroxyethoxy)ethoxy)quinazolin-6-ol
Catalogue No.:PA 05 0141043
Molecular Formula : C20H19N3O4
Molecular Weight : 365.39
stdClass Object
(
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[weight] => 240.26
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Ethyl 3-hydroxy-4-(2-methoxyethoxy)benzoate
Catalogue No.:PA 05 0141044
Molecular Formula : C12H16O5
Molecular Weight : 240.26
stdClass Object
(
[pname] => (E)-3-chloro-3-(3-nitrophenyl)acrylaldehyde
[catalogue_number] => PA 05 0141045
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 211.6
[form] => C9H6ClNO3
[cas] => 1620397-61-6
[pslug] => 1620397-61-6-e-3-chloro-3-3-nitrophenyl-acrylaldehyde-pa050141045
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(E)-3-chloro-3-(3-nitrophenyl)acrylaldehyde
stdClass Object
(
[pname] => 3-(3-Nitrophenyl)-3-oxopropanal
[catalogue_number] => PA 05 0141046
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 193.16
[form] => C9H7NO4
[cas] => 154669-16-6
[pslug] => 154669-16-6-3-3-nitrophenyl-3-oxopropanal-pa050141046
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3-(3-Nitrophenyl)-3-oxopropanal
Catalogue No.:PA 05 0141046
Molecular Formula : C9H7NO4
Molecular Weight : 193.16
stdClass Object
(
[pname] => Desmethyl Erlotinib Carboxylate Acid
[catalogue_number] => PA 05 0141047
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 393.4
[form] => C21H19N3O5
[cas] => 882172-60-3
[pslug] => 882172-60-3-desmethyl-erlotinib-carboxylate-acid-pa050141047
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Desmethyl Erlotinib Carboxylate Acid
stdClass Object
(
[pname] => 4-(3-((6,7-bis(2-Methoxyethoxy)quinazolin-4-yl)amino)phenyl)-2-methylbut-3-yn-2-ol Hydrochloride
[catalogue_number] => PA 05 0501000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 487.98
[form] => C25H30ClN3O5
[cas] => 299912-59-7
[pslug] => 299912-59-7-4-3-6-7-bis-2-methoxyethoxy-quinazolin-4-yl-amino-phenyl-2-methylbut-3-yn-2-ol-hydrochloride-pa050501000
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4-(3-((6,7-bis(2-Methoxyethoxy)quinazolin-4-yl)amino)phenyl)-2-methylbut-3-yn-2-ol Hydrochloride
Catalogue No.:PA 05 0501000
Molecular Formula : C25H30ClN3O5
Molecular Weight : 487.98
stdClass Object
(
[pname] => Propyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate
[catalogue_number] => PA 05 0141048
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 327.38
[form] => C16H25NO6
[cas] => 2805078-67-3
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Propyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate
Catalogue No.:PA 05 0141048
Molecular Formula : C16H25NO6
Molecular Weight : 327.38
stdClass Object
(
[pname] => N-(3-Bromophenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine Hydrochloride
[catalogue_number] => PA 05 0501001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 484.78
[form] => C20H23BrClN3O4
[cas] => 2055840-41-8
[pslug] => 2055840-41-8-n-3-bromophenyl-6-7-bis-2-methoxyethoxy-quinazolin-4-amine-hydrochloride-pa050501001
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N-(3-Bromophenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine Hydrochloride
Catalogue No.:PA 05 0501001
Molecular Formula : C20H23BrClN3O4
Molecular Weight : 484.78
