exemestane
Metabolites
- Exemestane is used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women. It irreversibly binds to the active site of the enzyme resulting in permanent inhibition. It is an oral steroidal aromatase inhibitor.. Reference standards of Exemestane API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object
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[pname] => Exemestane - Impurity H
[catalogue_number] => PA 05 54510
[category_ids] => ,87,82,78,76,75,70,
[chemical_name] =>
[weight] => 298.42
[form] => C20H26O2
[cas] => 122370-91-6
[pslug] => 122370-91-6-exemestane-impurity-h-freebase-pa0554510
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Catalogue No.:PA 05 54510
Molecular Formula : C20H26O2
Molecular Weight : 298.42
stdClass Object
(
[pname] => Exemestane α-Spirooxirane
[catalogue_number] => PA 05 54520
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 312.4
[form] => C20H24O3
[cas] => 152764-24-4
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Exemestane α-Spirooxirane
stdClass Object
(
[pname] => Exemestane β-Spirooxirane
[catalogue_number] => PA 05 54530
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 312.4
[form] => C20H24O3
[cas] => 152764-31-3
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Exemestane β-Spirooxirane
stdClass Object
(
[pname] => Exemestane Diol Impurity
[catalogue_number] => PA 05 54600
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 330.42
[form] => C20H26O4
[cas] => 184972-11-0
[pslug] => 184972-11-0-exemestane-diol-impurity-pa0554600
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Catalogue No.:PA 05 54600
Molecular Formula : C20H26O4
Molecular Weight : 330.42
stdClass Object
(
[pname] => 6-Hydroxymethyl Exemestane-d3
[catalogue_number] => PA STI 047740
[category_ids] => ,98,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 315.42
[form] => C20H21D3O3
[cas] => NA
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6-Hydroxymethyl Exemestane-d3
Catalogue No.:PA STI 047740
Molecular Formula : C20H21D3O3
Molecular Weight : 315.42
stdClass Object
(
[pname] => 17β-Hydroxy Exemestane-d3
[catalogue_number] => PA STI 049020
[category_ids] => ,98,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 301.44
[form] => C20H23D3O2
[cas] => NA
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17β-Hydroxy Exemestane-d3
Catalogue No.:PA STI 049020
Molecular Formula : C20H23D3O2
Molecular Weight : 301.44
stdClass Object
(
[pname] => 17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
[catalogue_number] => PA STI 049030
[category_ids] => ,95,98,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 477.56
[form] => C26H31D3O8
[cas] => NA
[pslug] => 17-beta-hydroxy-exemestane-d3-17-o-beta-d-glucuronide-pasti049030
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17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
Catalogue No.:PA STI 049030
Molecular Formula : C26H31D3O8
Molecular Weight : 477.56
stdClass Object
(
[pname] => 17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester
[catalogue_number] => PA STI 049040
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[chemical_name] =>
[weight] => 617.7
[form] => C33H39D3O11
[cas] => NA
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17β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide 2,3,4-Triacetate Methyl Ester
stdClass Object
(
[pname] => Exemestane System Suitability Mixture
[catalogue_number] => PA 05 0541000
[category_ids] => ,80,71,76,75,93,78,70,82,
[chemical_name] =>
[weight] => 296.41
[form] => C20H24O2
[cas] => NA
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Exemestane System Suitability Mixture
Catalogue No.:PA 05 0541000
Molecular Formula : C20H24O2
Molecular Weight : 296.41
stdClass Object
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[pname] => 6β-Hydroxymethylandrosta-1,4-diene-3,17-dione
[catalogue_number] => PA 05 0541001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 314.43
[form] => C20H26O3
[cas] => 121021-51-0
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6β-Hydroxymethylandrosta-1,4-diene-3,17-dione
Catalogue No.:PA 05 0541001
Molecular Formula : C20H26O3
Molecular Weight : 314.43
stdClass Object
(
[pname] => Exemestane - Impurity C
[catalogue_number] => PA 05 0540030
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 308.42
[form] => C21H24O2
[cas] => 2130745-60-5
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Catalogue No.:PA 05 0540030
Molecular Formula : C21H24O2
Molecular Weight : 308.42
stdClass Object
(
[pname] => (8R,9S,13S,14S)-1-Hydroxy-4,13-dimethyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one
[catalogue_number] => PA 05 0541002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 284.4
[form] => C19H24O2
[cas] => 4954-08-9
[pslug] => 4954-08-9-8r-9s-13s-14s-1-hydroxy-4-13-dimethyl-6-7-8-9-11-12-13-14-15-16-decahydro-17h-cyclopenta-a-phenanthren-17-one-pa050541002
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(8R,9S,13S,14S)-1-Hydroxy-4,13-dimethyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one
stdClass Object
(
[pname] => ((8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate
[catalogue_number] => PA 05 0541004
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 392.51
[form] => C21H28O5S
[cas] => 861395-77-9
[pslug] => 861395-77-9-8r-9s-10r-13s-14s-10-13-dimethyl-3-17-dioxo-6-7-8-9-10-11-12-13-14-15-16-17-dodecahydro-3h-cyclopenta-a-phenanthren-6-yl-methyl-methanesulfonate-pa050541004
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((8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate
Catalogue No.:PA 05 0541004
Molecular Formula : C21H28O5S
Molecular Weight : 392.51
stdClass Object
(
[pname] => Exemestane - Impurity J
[catalogue_number] => PA 05 0540100
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 340.46
[form] => C22H28O3
[cas] => 1160599-91-6
[pslug] => 1160599-91-6-exemestane-impurity-j-pa050540100
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Catalogue No.:PA 05 0540100
Molecular Formula : C22H28O3
Molecular Weight : 340.46
stdClass Object
(
[pname] => Exemestane D4
[catalogue_number] => PA STI 089136
[category_ids] => ,98,75,76,78,70,82,
[chemical_name] =>
[weight] => 300.43
[form] => C20H20D4O2
[cas] => NA
[pslug] => exemestane-d4-pasti089136
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Catalogue No.:PA STI 089136
Molecular Formula : C20H20D4O2
Molecular Weight : 300.43
stdClass Object
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[pname] => Delta-1,6-methylene -17-hydroxyprogest
[catalogue_number] => PA 05 0541005
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 340.46
[form] => C22H28O3
[cas] => 1204325-01-8
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Delta-1,6-methylene -17-hydroxyprogest
Catalogue No.:PA 05 0541005
Molecular Formula : C22H28O3
Molecular Weight : 340.46
stdClass Object
(
[pname] => 6-Hydroxymethyl Exemestane
[catalogue_number] => PA 05 0541006
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 312.41
[form] => C20H24O3
[cas] => 152764-26-6
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6-Hydroxymethyl Exemestane
Catalogue No.:PA 05 0541006
Molecular Formula : C20H24O3
Molecular Weight : 312.41
stdClass Object
(
[pname] => 17-Beta-Hydroxy Exemestane Epoxide
[catalogue_number] => PA 05 0541007
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 314.43
[form] => C20H26O3
[cas] => 1331732-05-8
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17-Beta-Hydroxy Exemestane Epoxide
Catalogue No.:PA 05 0541007
Molecular Formula : C20H26O3
Molecular Weight : 314.43
stdClass Object
(
[pname] => (8R,9S,10R,13S,14S)-6-(Methoxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
[catalogue_number] => PA 05 0541008
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 328.45
[form] => C21H28O3
[cas] => 861398-01-8
[pslug] => 861398-01-8-8r-9s-10r-13s-14s-6-methoxymethyl-10-13-dimethyl-7-8-9-10-11-12-13-14-15-16-decahydro-3h-cyclopenta-a-phenanthrene-3-17-6h-dione-pa050541008
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(8R,9S,10R,13S,14S)-6-(Methoxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
Catalogue No.:PA 05 0541008
Molecular Formula : C21H28O3
Molecular Weight : 328.45
stdClass Object
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[pname] => 16-Methyleneandrosta-1,4-diene-3,17-dione
[catalogue_number] => PA 05 0541009
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 296.41
[form] => C20H24O2
[cas] => 2467590-81-2
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16-Methyleneandrosta-1,4-diene-3,17-dione
Catalogue No.:PA 05 0541009
Molecular Formula : C20H24O2
Molecular Weight : 296.41
stdClass Object
(
[pname] => Pregna-1,4-Diene-3-One, 17,20-Dihydroxy-6-Methylene
[catalogue_number] => PA 05 0541010
[category_ids] => ,76,75,78,70,82,87,
[chemical_name] =>
[weight] => 342.48
[form] => C22H30O3
[cas] => 1204325-02-9
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Pregna-1,4-Diene-3-One, 17,20-Dihydroxy-6-Methylene
Catalogue No.:PA 05 0541010
Molecular Formula : C22H30O3
Molecular Weight : 342.48
stdClass Object
(
[pname] => (8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde
[catalogue_number] => PA 05 0541011
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[weight] => 312.41
[form] => C20H24O3
[cas] => NA
[pslug] => 8r-9s-10r-13s-14s-10-13-dimethyl-3-17-dioxo-6-7-8-9-10-11-12-13-14-15-16-17-dodecahydro-3h-cyclopenta-a-phenanthrene-6-carbaldehyde-pa050541011
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(8R,9S,10R,13S,14S)-10,13-Dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde
Catalogue No.:PA 05 0541011
Molecular Formula : C20H24O3
Molecular Weight : 312.41
stdClass Object
(
[pname] => (8R,9S,10R,13S,14S)-17-Hydroxy-10,13-dimethyl-3-oxo-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde
[catalogue_number] => PA 05 0541012
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[weight] => 312.41
[form] => C20H24O3
[cas] => NA
[pslug] => 8r-9s-10r-13s-14s-17-hydroxy-10-13-dimethyl-3-oxo-8-9-10-11-12-13-14-15-16-17-decahydro-3h-cyclopenta-a-phenanthrene-6-carbaldehyde-pa050541012
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(8R,9S,10R,13S,14S)-17-Hydroxy-10,13-dimethyl-3-oxo-8,9,10,11,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-6-carbaldehyde
Catalogue No.:PA 05 0541012
Molecular Formula : C20H24O3
Molecular Weight : 312.41
stdClass Object
(
[pname] => (8R,9S,10R,13S,14S)-3-Ethoxy-10,13-dimethyl-6-methylene-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one
[catalogue_number] => PA 05 0541013
[category_ids] => ,87,75,76,78,70,82,
[chemical_name] =>
[weight] => 328.5
[form] => C22H32O2
[cas] => NA
[pslug] => 8r-9s-10r-13s-14s-3-ethoxy-10-13-dimethyl-6-methylene-1-2-3-6-7-8-9-10-11-12-13-14-15-16-tetradecahydro-17h-cyclopenta-a-phenanthren-17-one-pa050541013
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(8R,9S,10R,13S,14S)-3-Ethoxy-10,13-dimethyl-6-methylene-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one
stdClass Object
(
[pname] => ((6S,8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate
[catalogue_number] => PA 05 0541014
[category_ids] => ,87,75,76,78,70,82,
[chemical_name] =>
[weight] => 392.51
[form] => C21H28O5S
[cas] => NA
[pslug] => 6s-8r-9s-10r-13s-14s-10-13-dimethyl-3-17-dioxo-6-7-8-9-10-11-12-13-14-15-16-17-dodecahydro-3h-cyclopenta-a-phenanthren-6-yl-methyl-methanesulfonate-pa050541014
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((6S,8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-6-yl)methyl methanesulfonate
Catalogue No.:PA 05 0541014
Molecular Formula : C21H28O5S
Molecular Weight : 392.51
