ivabradine
Metabolites
- Ivabradine is used for the symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm who cannot take beta blockers. It is marketed under the trade name Corlanor. Reference standards of Ivabradine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => N-Demethyl Ivabradine-d6 Hydrochloride
[catalogue_number] => PA STI 028660
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[chemical_name] =>
[weight] => 497.06
[form] => C26H29D6ClN2O5
[cas] => NA
[pslug] => n-demethyl-ivabradine-d6-hydrochloride-pasti028660
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N-Demethyl Ivabradine-d6 Hydrochloride
Catalogue No.:PA STI 028660
Molecular Formula : C26H29D6ClN2O5
Molecular Weight : 497.06
stdClass Object
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[catalogue_number] => PA 09 0581000
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[weight] => 484.59
[form] => C27H36N2O6
[cas] => NA
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3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepine 3-Oxide
Catalogue No.:PA 09 0581000
Molecular Formula : C27H36N2O6
Molecular Weight : 484.59
stdClass Object
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[pname] => (S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione Oxalate
[catalogue_number] => PA 09 0581001
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[weight] => 572.61
[form] => C29H36N2O10
[cas] => NA
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(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione Oxalate
Catalogue No.:PA 09 0581001
Molecular Formula : C29H36N2O10
Molecular Weight : 572.61
stdClass Object
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[pname] => [[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]-carbamic acid ethyl ester
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[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]-carbamic acid ethyl ester
Catalogue No.:PA 09 0581002
Molecular Formula : C14H19NO4
Molecular Weight : 265.31
stdClass Object
(
[pname] => N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide
[catalogue_number] => PA 09 0581003
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[form] => C14H19NO3
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N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide
Catalogue No.:PA 09 0581003
Molecular Formula : C14H19NO3
Molecular Weight : 249.31
stdClass Object
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Ethyl (E)-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)formimidate
Catalogue No.:PA 09 0581004
Molecular Formula : C14H19NO3
Molecular Weight : 249.31
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3-(3-((((1R,3S,4R,6S,7S)-3,4-Dimethoxybicyclo[4.2.0]octan-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0581005
Molecular Formula : C27H42N2O5
Molecular Weight : 474.64
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3-(3-((((1S,3R,4S,6R,7S)-3,4-Dimethoxybicyclo[4.2.0]octan-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0581006
Molecular Formula : C27H42N2O5
Molecular Weight : 474.64
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[catalogue_number] => PA 09 0581007
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[weight] => 484.59
[form] => C27H36N2O6
[cas] => 2253977-80-7
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3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-5-hydroxy-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0581007
Molecular Formula : C27H36N2O6
Molecular Weight : 484.59
stdClass Object
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[pname] => 3-(3-((3-Chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
[catalogue_number] => PA 09 0581008
[category_ids] => ,75,76,78,70,82,
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[weight] => 505.05
[form] => C27H37ClN2O5
[cas] => NA
[pslug] => 3-3-3-chloro-2-3-4-dimethoxyphenyl-propyl-methyl-amino-propyl-7-8-dimethoxy-1-3-4-5-tetrahydro-2h-benzo-d-azepin-2-one-pa090581008
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3-(3-((3-Chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0581008
Molecular Formula : C27H37ClN2O5
Molecular Weight : 505.05
stdClass Object
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[pname] => 3-Hydroxy Ivabradine
[catalogue_number] => PA 09 0581009
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[chemical_name] =>
[weight] => 454.57
[form] => C26H34N2O5
[cas] => 304464-98-0
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Catalogue No.:PA 09 0581009
Molecular Formula : C26H34N2O5
Molecular Weight : 454.57
stdClass Object
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[catalogue_number] => PA 09 0581010
[category_ids] => ,75,76,78,70,82,
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[weight] => 483.61
[form] => C28H37NO6
[cas] => NA
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3-(2,3-Dimethoxy-6-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-7-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine oxide
Catalogue No.:PA 09 0581010
Molecular Formula : C28H37NO6
Molecular Weight : 483.61
stdClass Object
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[catalogue_number] => PA 09 0581011
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[weight] => 505.05
[form] => C27H37ClN2O5
[cas] => 1796933-38-4
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3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one hydrochloride
Catalogue No.:PA 09 0581011
Molecular Formula : C27H37ClN2O5
Molecular Weight : 505.05
stdClass Object
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[catalogue_number] => PA 09 0581012
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[weight] => 237.26
[form] => C12H15NO4
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2-(3,4-Dimethoxyphenyl)-N-(2-oxoethyl)acetamide
Catalogue No.:PA 09 0581012
Molecular Formula : C12H15NO4
Molecular Weight : 237.26
stdClass Object
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[catalogue_number] => PA 09 0581013
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[weight] => 189.21
[form] => C11H11NO2
[cas] => 1132076-14-2
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4,5-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
Catalogue No.:PA 09 0581013
Molecular Formula : C11H11NO2
Molecular Weight : 189.21
stdClass Object
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[weight] => 270.13
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3-(3-Bromo-4,5-dimethoxyphenyl)propanenitrile
Catalogue No.:PA 09 0581014
Molecular Formula : C11H12BrNO2
Molecular Weight : 270.13
stdClass Object
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[catalogue_number] => PA 09 0581015
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[weight] => 412.49
[form] => C23H28N2O5
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1-(((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-3-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)urea
Catalogue No.:PA 09 0581015
Molecular Formula : C23H28N2O5
Molecular Weight : 412.49
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[pname] => N-Nitroso N-Desmethyl DEBA
[catalogue_number] => PA 09 0581016
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[weight] => 204.27
[form] => C9H20N2O3
[cas] => NA
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N-Nitroso N-Desmethyl DEBA
Catalogue No.:PA 09 0581016
Molecular Formula : C9H20N2O3
Molecular Weight : 204.27
stdClass Object
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[pname] => N-Nitroso N-Desmethyl Ivabradine
[catalogue_number] => PA 09 0581017
[category_ids] => ,70,75,76,78,82,162,
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[weight] => 483.57
[form] => C26H33N3O6
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N-Nitroso N-Desmethyl Ivabradine
Catalogue No.:PA 09 0581017
Molecular Formula : C26H33N3O6
Molecular Weight : 483.57
stdClass Object
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[pname] => (S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide
[catalogue_number] => PA 09 0581018
[category_ids] => ,78,75,70,82,76,
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[weight] => 249.31
[form] => C14H19NO3
[cas] => 2512206-14-1
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(S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylacetamide
Catalogue No.:PA 09 0581018
Molecular Formula : C14H19NO3
Molecular Weight : 249.31
stdClass Object
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[pname] => (R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
[catalogue_number] => PA 09 0581019
[category_ids] => ,82,78,76,75,70,
[chemical_name] =>
[weight] => 454.57
[form] => C26H34N2O5
[cas] => 2724918-59-4
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(R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)amino)propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
Catalogue No.:PA 09 0581019
Molecular Formula : C26H34N2O5
Molecular Weight : 454.57
stdClass Object
(
[pname] => 3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxydecahydro-2H-benzo[d]azepin-2-one Hydrochloride
[catalogue_number] => PA 09 0581020
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 511.1
[form] => C27H43ClN2O5
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3-(3-((((S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxydecahydro-2H-benzo[d]azepin-2-one Hydrochloride
stdClass Object
(
[pname] => (S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,5-dihydro-2H-benzo[d]azepine-2,4(3H)-dione
[catalogue_number] => PA 09 0581021
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 482.58
[form] => C27H34N2O6
[cas] => 1629315-02-1
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(S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1,5-dihydro-2H-benzo[d]azepine-2,4(3H)-dione
Catalogue No.:PA 09 0581021
Molecular Formula : C27H34N2O6
Molecular Weight : 482.58
stdClass Object
(
[pname] => (S)-3-Chloro-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylpropan-1-amine
[catalogue_number] => PA 09 0581022
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 283.8
[form] => C15H22ClNO2
[cas] => 1031767-71-1
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(S)-3-Chloro-N-((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylpropan-1-amine
stdClass Object
(
[pname] => 8-Demethyl Ivabradine Hydrochloride
[catalogue_number] => PA 09 0581031
[category_ids] => ,79,69,76,75,78,70,82,
[chemical_name] =>
[weight] => 491.03
[form] => C26H35ClN2O5
[cas] => NA
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8-Demethyl Ivabradine Hydrochloride
Catalogue No.:PA 09 0581031
Molecular Formula : C26H35ClN2O5
Molecular Weight : 491.03
stdClass Object
(
[pname] => (R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2,3-dihydro-1H-benzo[d]azepine-1,4(5H)-dione
[catalogue_number] => PA 09 0581032
[category_ids] => ,79,69,76,75,78,70,82,
[chemical_name] =>
[weight] => 482.58
[form] => C27H34N2O6
[cas] => NA
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(R)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-2,3-dihydro-1H-benzo[d]azepine-1,4(5H)-dione
Catalogue No.:PA 09 0581032
Molecular Formula : C27H34N2O6
Molecular Weight : 482.58
stdClass Object
(
[pname] => 7-Demethyl Ivabradine Hydrochloride
[catalogue_number] => PA 09 0581033
[category_ids] => ,79,69,76,75,78,70,82,
[chemical_name] =>
[weight] => 491.03
[form] => C26H35ClN2O5
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7-Demethyl Ivabradine Hydrochloride
Catalogue No.:PA 09 0581033
Molecular Formula : C26H35ClN2O5
Molecular Weight : 491.03
