Lapatinib Ditosylate Hydrate is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2. Reference standards of Lapatinib Ditosylate Hydrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Lapatinib Ditosylate Hydrate - API Standards [catalogue_number] => PA 39 05000 [category_ids] => ,80,71,76,75,78,70,82,88, [chemical_name] => [weight] => 943.48 [form] => C43H44ClFN4O11S3 [cas] => 388082-78-8 [pslug] => 388082-78-8-lapatinib-ditosylate-hydrate-api-pa3905000 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 05000
CAS :
Molecular Formula : C43H44ClFN4O11S3
Molecular Weight : 943.48
stdClass Object ( [pname] => O-De(3-fluorobenzyl) Lapatinib [catalogue_number] => PA 39 05510 [category_ids] => ,80,71,76,75,78,70,82,88, [chemical_name] => [weight] => 472.94 [form] => C22H21ClN4O4S [cas] => 1268997-70-1 [pslug] => 1268997-70-1-o-de-3-fluorobenzyl-lapatinib-pa3905510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 05510
Molecular Formula : C22H21ClN4O4S
Molecular Weight : 472.94
stdClass Object ( [pname] => N-De[2-(methylsulfonyl)ethyl] Lapatinib [catalogue_number] => PA 39 05520 [category_ids] => ,80,71,76,75,78,70,82,88, [chemical_name] => [weight] => 474.91 [form] => C26H20ClFN4O2 [cas] => 697299-82-4 [pslug] => 697299-82-4-n-de-2-methylsulfonyl-ethyl-lapatinib-pa3905520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 05520
Molecular Formula : C26H20ClFN4O2
Molecular Weight : 474.91
stdClass Object ( [pname] => 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carboxylic Acid [catalogue_number] => PA 39 05530 [category_ids] => ,80,71,76,75,78,70,82,88, [chemical_name] => [weight] => 489.88 [form] => C26H17ClFN3O4 [cas] => 1152131-73-1 [pslug] => 1152131-73-1-5-4-3-chloro-4-3-fluorobenzyl-oxy-phenyl-amino-quinazolin-6-yl-furan-2-carboxylic-acid-pa3905530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 05530
Molecular Formula : C26H17ClFN3O4
Molecular Weight : 489.88
stdClass Object ( [pname] => Des(sulfonylethyl)amino Hydroxy Lapatinib [catalogue_number] => PA 39 05540 [category_ids] => ,80,71,76,75,78,70,82, [chemical_name] => [weight] => 475.9 [form] => C26H19ClFN3O3 [cas] => 320337-48-2 [pslug] => 320337-48-2-des-sulfonylethyl-amino-hydroxy-lapatinib-pa3905540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 05540
Molecular Formula : C26H19ClFN3O3
Molecular Weight : 475.9
stdClass Object ( [pname] => N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine [catalogue_number] => PA 39 0051000 [category_ids] => 82,78,76,75,70 [chemical_name] => [weight] => 581.06 [form] => C29H26ClFN4O4S [cas] => 1393112-45-2 [pslug] => 1393112-45-2-n-3-chloro-4-2-fluorobenzyl-oxy-phenyl-6-5-2-methylsulfonyl-ethyl-amino-methyl-furan-2-yl-quinazolin-4-amine-pa390051000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051000
Molecular Formula : C29H26ClFN4O4S
Molecular Weight : 581.06
stdClass Object ( [pname] => N-(4-(4-Fluorobenzyloxy)-3-chlorophenyl)-6-(5-((2-(methylsulfonyl)ethylamino) methyl)furan-2-yl)quinazolin-4-amine [catalogue_number] => PA 39 0051001 [category_ids] => ,75,76,70,78,82, [chemical_name] => [weight] => 581.06 [form] => C29H26ClFN4O4S [cas] => 1026818-86-9 [pslug] => 1026818-86-9-n-4-4-fluorobenzyloxy-3-chlorophenyl-6-5-2-methylsulfonyl-ethylamino-methyl-furan-2-yl-quinazolin-4-amine-pa390051001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051001
stdClass Object ( [pname] => 3-Chloro-4-(3-fluorobenzyloxy)aniline [catalogue_number] => PA 39 0051002 [category_ids] => ,75,76,70,78,82, [chemical_name] => [weight] => 251.69 [form] => C13H11ClFNO [cas] => 202197-26-0 [pslug] => 202197-26-0-3-chloro-4-3-fluorobenzyloxy-aniline-pa390051002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051002
Molecular Formula : C13H11ClFNO
Molecular Weight : 251.69
stdClass Object ( [pname] => Deschloro Lapatinib [catalogue_number] => PA 39 0051004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 546.62 [form] => C29H27FN4O4S [cas] => 633370-23-7 [pslug] => 633370-23-7-deschloro-lapatinib-pa390051004 [latest_product] => 1 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051004
Molecular Formula : C29H27FN4O4S
Molecular Weight : 546.62
stdClass Object ( [pname] => N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine [catalogue_number] => PA 39 0051005 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 505.72 [form] => C21H14ClFIN3O [cas] => 231278-20-9 [pslug] => 231278-20-9-n-3-chloro-4-3-fluorophenyl-methoxy-phenyl-6-iodo-4-quinazolinamine-pa390051005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051005
Molecular Formula : C21H14ClFIN3O
Molecular Weight : 505.72
stdClass Object ( [pname] => N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate) [catalogue_number] => PA 39 0051006 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 891.01 [form] => C43H43FN4O10S3 [cas] => NA [pslug] => n-4-3-fluorobenzyl-oxy-phenyl-6-5-2-methylsulfonyl-ethyl-amino-methyl-furan-2-yl-quinazolin-4-amine-bis-4-methylbenzenesulfonate-pa390051006 [latest_product] => 1 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051006
Molecular Formula : C43H43FN4O10S3
Molecular Weight : 891.01
stdClass Object ( [pname] => 4-((3-Fluorobenzyl)oxy)aniline [catalogue_number] => PAI 39 005001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 217.24 [form] => C13H12FNO [cas] => 202197-25-9 [pslug] => 202197-25-9-4-3-fluorobenzyl-oxy-aniline-pai39005001 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 39 005001
Molecular Formula : C13H12FNO
Molecular Weight : 217.24
stdClass Object ( [pname] => 4-((3-Fluorobenzyl)oxy)aniline Hydrochloride [catalogue_number] => PAI 39 005002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 253.7 [form] => C13H13ClFNO [cas] => 57181-87-0 [pslug] => 57181-87-0-4-3-fluorobenzyl-oxy-aniline-hydrochloride-pai39005002 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 39 005002
Molecular Formula : C13H13ClFNO
Molecular Weight : 253.7
stdClass Object ( [pname] => N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine [catalogue_number] => PAI 39 005003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 471.27 [form] => C21H15FIN3O [cas] => 231278-25-4 [pslug] => 231278-25-4-n-4-3-fluorobenzyl-oxy-phenyl-6-iodoquinazolin-4-amine-pai39005003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 39 005003
Molecular Formula : C21H15FIN3O
Molecular Weight : 471.27
stdClass Object ( [pname] => 5-(4-((4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde [catalogue_number] => PAI 39 005004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 439.45 [form] => C26H18FN3O3 [cas] => 746591-42-4 [pslug] => 746591-42-4-5-4-4-3-fluorobenzyl-oxy-phenyl-amino-quinazolin-6-yl-furan-2-carbaldehyde-pai39005004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PAI 39 005004
Molecular Formula : C26H18FN3O3
Molecular Weight : 439.45
stdClass Object ( [pname] => N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-((((5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine [catalogue_number] => PA 39 0051008 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 1038.95 [form] => C55H43Cl2F2N7O6S [cas] => 2172855-57-9 [pslug] => 2172855-57-9-n-3-chloro-4-3-fluorobenzyl-oxy-phenyl-6-5-5-4-3-chloro-4-3-fluorobenzyl-oxy-phenyl-amino-quinazolin-6-yl-furan-2-yl-methyl-2-methylsulfonyl-ethyl-amino-methyl-furan-2-yl-quinazolin-4-amine-pa390051008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 39 0051008
Molecular Formula : C55H43Cl2F2N7O6S
Molecular Weight : 1038.95
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