Pazopanib-impurities | Pharmaffiliates

pazopanib

Pazopanib is a drug used in the treatment for advanced/metastatic renal cell carcinoma and advanced soft tissue sarcomas. It is a potent and selective multi-targeted receptor tyrosine kinase inhibitor.Reference standards of Pazopanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => 2,3-Dimethyl-6-nitro-2H-indazole
    [catalogue_number] => PA 43 36570
    [category_ids] => ,76,75,
    [chemical_name] => 
    [weight] => 191.19
    [form] => C9H9N3O2
    [cas] => 444731-73-1
    [pslug] => 444731-73-1-2-3-dimethyl-6-nitro-2h-indazole-pa4336570
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PA 43 36570

2,3-Dimethyl-6-nitro-2H-indazole


  • Catalogue No.:PA 43 36570

  • CAS :

    444731-73-1

  • Molecular Formula : C9H9N3O2

  • Molecular Weight : 191.19

stdClass Object
(
    [pname] => N-Demethyl Pazopanib
    [catalogue_number] => PA 43 36650
    [category_ids] => ,76,70,78,70,82,
    [chemical_name] => 
    [weight] => 423.5
    [form] => C20H21N7O2S
    [cas] => 1252927-47-1
    [pslug] => 1252927-47-1-n-demethyl-pazopanib-pa4336650
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PA 43 36650

N-Demethyl Pazopanib


  • Catalogue No.:PA 43 36650

  • CAS :

    1252927-47-1

  • Molecular Formula : C20H21N7O2S

  • Molecular Weight : 423.5

stdClass Object
(
    [pname] => N2,N4-Bis(2,3-Dimethyl-2H-indazol-6-yl)-2,4-pyrimidinediamine
    [catalogue_number] => PA 43 36660
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 398.47
    [form] => C22H22N8
    [cas] => 1226499-98-4
    [pslug] => 1226499-98-4-n2-n4-bis-2-3-dimethyl-2h-indazol-6-yl-2-4-pyrimidinediamine-pa4336660
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PA 43 36660

N2,N4-Bis(2,3-Dimethyl-2H-indazol-6-yl)-2,4-pyrimidinediamine


  • Catalogue No.:PA 43 36660

  • CAS :

    1226499-98-4

  • Molecular Formula : C22H22N8

  • Molecular Weight : 398.47

stdClass Object
(
    [pname] => N,2,3-Trimethyl-N-(2-((4-methyl-3-sulfamoylphenyl)amino)pyrimidin-4-yl)-2H-indazol-6-amine Oxide
    [catalogue_number] => PA 43 36670
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 453.52
    [form] => C21H23N7O3S
    [cas] => 1821666-73-2
    [pslug] => 1821666-73-2-n-2-3-trimethyl-n-2-4-methyl-3-sulfamoylphenyl-amino-pyrimidin-4-yl-2h-indazol-6-amine-oxide-pa4336670
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PA 43 36670

N,2,3-Trimethyl-N-(2-((4-methyl-3-sulfamoylphenyl)amino)pyrimidin-4-yl)-2H-indazol-6-amine Oxide


  • Catalogue No.:PA 43 36670

  • CAS :

    1821666-73-2

  • Molecular Formula : C21H23N7O3S

  • Molecular Weight : 453.52

stdClass Object
(
    [pname] => 2,3-Dimethyl-6-(methyl(2-((4-methyl-3-sulfamoylphenyl)amino)pyrimidin-4-yl)amino)-2H-indazole 2-oxide
    [catalogue_number] => PA 43 36680
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 453.52
    [form] => C21H23N7O3S
    [cas] => 1821666-74-3
    [pslug] => 1821666-74-3-2-3-dimethyl-6-methyl-2-4-methyl-3-sulfamoylphenyl-amino-pyrimidin-4-yl-amino-2h-indazole-2-oxide-pa4336680
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PA 43 36680

2,3-Dimethyl-6-(methyl(2-((4-methyl-3-sulfamoylphenyl)amino)pyrimidin-4-yl)amino)-2H-indazole 2-oxide


  • Catalogue No.:PA 43 36680

  • CAS :

    1821666-74-3

  • Molecular Formula : C21H23N7O3S

  • Molecular Weight : 453.52

stdClass Object
(
    [pname] => 5-((2-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-4-yl)amino)-2-methylbenzenesulfonamide
    [catalogue_number] => PA 43 36690
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 437.52
    [form] => C21H23N7O2S
    [cas] => 2369664-19-5
    [pslug] => 2369664-19-5-5-2-2-3-dimethyl-2h-indazol-6-yl-methyl-amino-pyrimidin-4-yl-amino-2-methylbenzenesulfonamide-pa4336690
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PA 43 36690

5-((2-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-4-yl)amino)-2-methylbenzenesulfonamide


  • Catalogue No.:PA 43 36690

  • CAS :

    2369664-19-5

  • Molecular Formula : C21H23N7O2S

  • Molecular Weight : 437.52

stdClass Object
(
    [pname] => 2-Methyl-5-((4-(methylamino)pyrimidin-2-yl)amino)benzenesulfonamide
    [catalogue_number] => PA 43 0361000
    [category_ids] => 75,76,78,82
    [chemical_name] => 
    [weight] => 293.35
    [form] => C12H15N5O2S
    [cas] => 1821666-70-9
    [pslug] => 1821666-70-9-2-methyl-5-4-methylamino-pyrimidin-2-yl-amino-benzenesulfonamide-pa430361000
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PA 43 0361000

2-Methyl-5-((4-(methylamino)pyrimidin-2-yl)amino)benzenesulfonamide


  • Catalogue No.:PA 43 0361000

  • CAS :

    1821666-70-9

  • Molecular Formula : C12H15N5O2S

  • Molecular Weight : 293.35

stdClass Object
(
    [pname] => N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methylpyrimidine-2,4-diamine
    [catalogue_number] => PA 43 0361001
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 268.32
    [form] => C14H16N6
    [cas] => 1821666-71-0
    [pslug] => 1821666-71-0-n4-2-3-dimethyl-2h-indazol-6-yl-n4-methylpyrimidine-2-4-diamine-pa430361001
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PA 43 0361001

N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methylpyrimidine-2,4-diamine


  • Catalogue No.:PA 43 0361001

  • CAS :

    1821666-71-0

  • Molecular Formula : C14H16N6

  • Molecular Weight : 268.32

stdClass Object
(
    [pname] => 5-((4-((1,2-Dihydroazeto[1,2-b]indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide
    [catalogue_number] => PA 43 0361002
    [category_ids] => 82,78,76,75
    [chemical_name] => 
    [weight] => 435.51
    [form] => C21H21N7O2S
    [cas] => 1821666-72-1
    [pslug] => 1821666-72-1-5-4-1-2-dihydroazeto-1-2-b-indazol-6-yl-methyl-amino-pyrimidin-2-yl-amino-2-methylbenzenesulfonamide-pa430361002
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PA 43 0361002

5-((4-((1,2-Dihydroazeto[1,2-b]indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide


  • Catalogue No.:PA 43 0361002

  • CAS :

    1821666-72-1

  • Molecular Formula : C21H21N7O2S

  • Molecular Weight : 435.51

stdClass Object
(
    [pname] => N-(2-Methoxypyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine
    [catalogue_number] => PA 43 0361003
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 283.34
    [form] => C15H17N5O
    [cas] => 1296888-47-5
    [pslug] => 1296888-47-5-n-2-methoxypyrimidin-4-yl-n-2-3-trimethyl-2h-indazol-6-amine-pa430361003
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PA 43 0361003

N-(2-Methoxypyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine


  • Catalogue No.:PA 43 0361003

  • CAS :

    1296888-47-5

  • Molecular Formula : C15H17N5O

  • Molecular Weight : 283.34

stdClass Object
(
    [pname] => 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)(hydroxy)amino)-2-methylbenzenesulfonamide
    [catalogue_number] => PA 43 0361004
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 453.52
    [form] => C21H23N7O3S
    [cas] => NA
    [pslug] => 5-4-2-3-dimethyl-2h-indazol-6-yl-methyl-amino-pyrimidin-2-yl-hydroxy-amino-2-methylbenzenesulfonamide-pa430361004
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PA 43 0361004

5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)(hydroxy)amino)-2-methylbenzenesulfonamide


  • Catalogue No.:PA 43 0361004

  • CAS :

    NA

  • Molecular Formula : C21H23N7O3S

  • Molecular Weight : 453.52

stdClass Object
(
    [pname] => 3-Methyl-6-nitroindazole
    [catalogue_number] => PA 43 0361005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 177.16
    [form] => C8H7N3O2
    [cas] => 6494-19-5
    [pslug] => 6494-19-5-3-methyl-6-nitroindazole-pa430361005
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PA 43 0361005

3-Methyl-6-nitroindazole


  • Catalogue No.:PA 43 0361005

  • CAS :

    6494-19-5

  • Molecular Formula : C8H7N3O2

  • Molecular Weight : 177.16

stdClass Object
(
    [pname] => 2,3-Dimethyl-2H-indazol-6-amine hydrochloride
    [catalogue_number] => PA 43 0361006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 197.67
    [form] => C9H12ClN3
    [cas] => 635702-60-2
    [pslug] => 635702-60-2-2-3-dimethyl-2h-indazol-6-amine-hydrochloride-pa430361006
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PA 43 0361006

2,3-Dimethyl-2H-indazol-6-amine hydrochloride


  • Catalogue No.:PA 43 0361006

  • CAS :

    635702-60-2

  • Molecular Formula : C9H12ClN3

  • Molecular Weight : 197.67

stdClass Object
(
    [pname] => 5-Amino-N-(4-(bis(5-amino-2-methylphenyl)methyl)phenyl)-2-methylbenzenesulfonamide
    [catalogue_number] => PA 43 0361008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 486.63
    [form] => C28H30N4O2S
    [cas] => 1226500-00-0
    [pslug] => 1226500-00-0-5-amino-n-4-bis-5-amino-2-methylphenyl-methyl-phenyl-2-methylbenzenesulfonamide-pa430361008
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PA 43 0361008

5-Amino-N-(4-(bis(5-amino-2-methylphenyl)methyl)phenyl)-2-methylbenzenesulfonamide


  • Catalogue No.:PA 43 0361008

  • CAS :

    1226500-00-0

  • Molecular Formula : C28H30N4O2S

  • Molecular Weight : 486.63

stdClass Object
(
    [pname] => 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)(nitroso)amino)-2-methylbenzenesulfonamide
    [catalogue_number] => PA 43 0361009
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 466.52
    [form] => C21H22N8O3S
    [cas] => NA
    [pslug] => 5-4-2-3-dimethyl-2h-indazol-6-yl-methyl-amino-pyrimidin-2-yl-nitroso-amino-2-methylbenzenesulfonamide-pa430361009
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PA 43 0361009

5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)(nitroso)amino)-2-methylbenzenesulfonamide


  • Catalogue No.:PA 43 0361009

  • CAS :

    NA

  • Molecular Formula : C21H22N8O3S

  • Molecular Weight : 466.52

stdClass Object
(
    [pname] => 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid
    [catalogue_number] => PA 43 0361016
    [category_ids] => ,75,76,80,71,78,82,
    [chemical_name] => 
    [weight] => 438.51
    [form] => C21H22N6O3S
    [cas] => 2795176-90-6
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PA 43 0361016

5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonic Acid


  • Catalogue No.:PA 43 0361016

  • CAS :

    2795176-90-6

  • Molecular Formula : C21H22N6O3S

  • Molecular Weight : 438.51