salmeterol
Salmeterol is used for the treatment of moderate-to-severe persistent asthma. It is a long-acting β2 adrenergic receptor agonist (LABA) that acts as a bronchodilator. Salmeterol was first marketed and manufactured by Glaxo.Reference standards of Salmeterol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Salmeterol - API Standards
Catalogue No.:PA 19 38000
Molecular Formula : C25H37NO4
Molecular Weight : 415.57
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Salmeterol Xinafoate - API Standards
Catalogue No.:PA 19 38510
Molecular Formula : C36H45NO7
Molecular Weight : 603.74
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Catalogue No.:PA 19 38010
Molecular Formula : C19H25NO3
Molecular Weight : 315.41
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[catalogue_number] => PA 19 38020
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Catalogue No.:PA 19 38020
Molecular Formula : C23H33NO4
Molecular Weight : 387.51
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[catalogue_number] => PA 19 38030
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[form] => C24H35NO4
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Catalogue No.:PA 19 38030
Molecular Formula : C24H35NO4
Molecular Weight : 401.54
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Catalogue No.:PA 19 38050
Molecular Formula : C25H37NO4
Molecular Weight : 415.57
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[pname] => Salmeterol - Impurity F
[catalogue_number] => PA 19 38060
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Catalogue No.:PA 19 38060
Molecular Formula : C25H37NO3
Molecular Weight : 399.57
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[weight] => 585.73
[form] => C36H43NO6
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Salmeterol Xinafoate Adduct Impurity
Catalogue No.:PA 19 38520
Molecular Formula : C36H43NO6
Molecular Weight : 585.73
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[pname] => [6-(4-Phenylbutoxy)hexyl]benzylamine
[catalogue_number] => PA 19 0381000
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[weight] => 339.52
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[6-(4-Phenylbutoxy)hexyl]benzylamine
Catalogue No.:PA 19 0381000
Molecular Formula : C23H33NO
Molecular Weight : 339.52
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Salmeterol System Suitability
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Salmeterol Resolution Check
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[pname] => Salmeterol-d4
[catalogue_number] => PA STI 088886
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[weight] => 419.6
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[pname] => Methyl (R)-2-(benzyloxy)-5-(2-bromo-1-hydroxyethyl)benzoate
[catalogue_number] => PA 19 0381003
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[weight] => 365.22
[form] => C17H17BrO4
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Methyl (R)-2-(benzyloxy)-5-(2-bromo-1-hydroxyethyl)benzoate
Catalogue No.:PA 19 0381003
Molecular Formula : C17H17BrO4
Molecular Weight : 365.22
stdClass Object
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[pname] => 2-(Benzyl(6-(4-phenylbutoxy)hexyl)amino)-1-(4-(benzyloxy)-3-(hydroxymethyl)phenyl)ethan-1-ol
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[form] => C39H49NO4
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2-(Benzyl(6-(4-phenylbutoxy)hexyl)amino)-1-(4-(benzyloxy)-3-(hydroxymethyl)phenyl)ethan-1-ol
Catalogue No.:PA 19 0381004
Molecular Formula : C39H49NO4
Molecular Weight : 595.82
stdClass Object
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[pname] => N-Benzyl-4-phenylbutan-1-amine hydrochloride
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N-Benzyl-4-phenylbutan-1-amine hydrochloride
Catalogue No.:PA 19 0381005
Molecular Formula : C17H22ClN
Molecular Weight : 275.82
stdClass Object
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[pname] => 4-(1-Hydroxy-2-((2-hydroxy-4-(1-hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)benzyl)(6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol
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[weight] => 813.13
[form] => C50H72N2O7
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4-(1-Hydroxy-2-((2-hydroxy-4-(1-hydroxy-2-((6-(4-phenylbutoxy)hexyl)amino)ethyl)benzyl)(6-(4-phenylbutoxy)hexyl)amino)ethyl)-2-(hydroxymethyl)phenol
Catalogue No.:PA 19 0381006
Molecular Formula : C50H72N2O7
Molecular Weight : 813.13
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[catalogue_number] => PA 19 0381007
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[weight] => 323.39
[form] => C17H25NO5
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Tert-Butyl (S)-(2-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)-2-hydroxyethyl)carbamate
Catalogue No.:PA 19 0381007
Molecular Formula : C17H25NO5
Molecular Weight : 323.39
stdClass Object
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[pname] => N-(2-Hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)-N-(6-(4-phenylbutoxy)hexyl)nitrous Amide
[catalogue_number] => PA 19 0381008
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[weight] => 444.57
[form] => C25H36N2O5
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N-(2-Hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)-N-(6-(4-phenylbutoxy)hexyl)nitrous Amide
Catalogue No.:PA 19 0381008
Molecular Formula : C25H36N2O5
Molecular Weight : 444.57