afatinib
Miscellaneous compounds
- afatinib is a protein kinase inhibitor, it is used for the treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It is also known as Gilotrif and Giotrif. Reference standards of Afatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => (S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
[catalogue_number] => PA 28 02680
[category_ids] => ,79,80,71,84,
[chemical_name] =>
[weight] => 502.39
[form] => C24H25Cl2N5O3
[cas] => 2223677-63-0
[pslug] => 2223677-63-0-s-e-n-4-3-4-dichlorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802680
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(S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Catalogue No.:PA 28 02680
Molecular Formula : C24H25Cl2N5O3
Molecular Weight : 502.39
stdClass Object
(
[pname] => (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
[catalogue_number] => PA 28 02700
[category_ids] => ,79,80,71,84,
[chemical_name] =>
[weight] => 358.39
[form] => C18H22N4O4
[cas] => NA
[pslug] => s-e-4-dimethylamino-n-4-hydroxy-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-but-2-enamide-pa2802700
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(S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
Catalogue No.:PA 28 02700
Molecular Formula : C18H22N4O4
Molecular Weight : 358.39
