Afatinib-Impurities | Pharmaffiliates

afatinib

afatinib is a protein kinase inhibitor, it is used for the treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), developed by Boehringer Ingelheim. It is also known as Gilotrif and Giotrif. Reference standards of Afatinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Afatinib - API Standards 
    [catalogue_number] => PA 28 02000
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 485.94
    [form] => C24H25ClFN5O3
    [cas] => 850140-72-6
    [pslug] => 850140-72-6-afatinib-api-pa2802000
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PA 28 02000

Afatinib - API Standards


  • Catalogue No.:PA 28 02000

  • CAS :

    850140-72-6

  • Molecular Formula : C24H25ClFN5O3

  • Molecular Weight : 485.94

stdClass Object
(
    [pname] => N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
    [catalogue_number] => PA 28 02510
    [category_ids] => 71,79,80,82,78,70
    [chemical_name] => 
    [weight] => 353.14
    [form] => C14H7Cl2FN4O2
    [cas] => 2512206-82-3
    [pslug] => 2512206-82-3-n-3-4-dichlorophenyl-7-fluoro-6-nitroquinazolin-4-amine-pa2802510
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PA 28 02510

N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine


  • Catalogue No.:PA 28 02510

  • CAS :

    2512206-82-3

  • Molecular Formula : C14H7Cl2FN4O2

  • Molecular Weight : 353.14

stdClass Object
(
    [pname] => (S)-N4-(4-Fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
    [catalogue_number] => PA 28 02520
    [category_ids] => 69,70,78,82,79,71
    [chemical_name] => 
    [weight] => 340.35
    [form] => C18H17FN4O2
    [cas] => 2413212-07-2
    [pslug] => 2413212-07-2-s-n4-4-fluorophenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa2802520
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PA 28 02520

(S)-N4-(4-Fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine


  • Catalogue No.:PA 28 02520

  • CAS :

    2413212-07-2

  • Molecular Formula : C18H17FN4O2

  • Molecular Weight : 340.35

stdClass Object
(
    [pname] => (S)-N4-phenyl-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
    [catalogue_number] => PA 28 02530
    [category_ids] => 71,79,82,78,70,69
    [chemical_name] => 
    [weight] => 322.36
    [form] => C18H18N4O2
    [cas] => 2413212-08-3
    [pslug] => 2413212-08-3-s-n4-phenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa2802530
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PA 28 02530

(S)-N4-phenyl-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine


  • Catalogue No.:PA 28 02530

  • CAS :

    2413212-08-3

  • Molecular Formula : C18H18N4O2

  • Molecular Weight : 322.36

stdClass Object
(
    [pname] => (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
    [catalogue_number] => PA 28 02540
    [category_ids] => 69,70,78,82,79,71
    [chemical_name] => 
    [weight] => 356.81
    [form] => C18H17ClN4O2
    [cas] => 2413212-09-4
    [pslug] => 2413212-09-4-s-n4-3-chlorophenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa2802540
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PA 28 02540

(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine


  • Catalogue No.:PA 28 02540

  • CAS :

    2413212-09-4

  • Molecular Formula : C18H17ClN4O2

  • Molecular Weight : 356.81

stdClass Object
(
    [pname] => (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
    [catalogue_number] => PA 28 02550
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 374.8
    [form] => C18H16ClFN4O2
    [cas] => 314771-76-1
    [pslug] => 314771-76-1-s-n4-3-chloro-4-fluorophenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa2802550
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PA 28 02550

(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine


  • Catalogue No.:PA 28 02550

  • CAS :

    314771-76-1

  • Molecular Formula : C18H16ClFN4O2

  • Molecular Weight : 374.8

stdClass Object
(
    [pname] => (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide
    [catalogue_number] => PA 28 02560
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 402.81
    [form] => C19H16ClFN4O3
    [cas] => 2223677-60-7
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PA 28 02560

(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide


  • Catalogue No.:PA 28 02560

  • CAS :

    2223677-60-7

  • Molecular Formula : C19H16ClFN4O3

  • Molecular Weight : 402.81

stdClass Object
(
    [pname] => (S)-N-(((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)methylene)-N-methylmethanaminium
    [catalogue_number] => PA 28 02570
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 430.88
    [form] => C21H22ClFN5O2
    [cas] => NA
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PA 28 02570

(S)-N-(((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)methylene)-N-methylmethanaminium


  • Catalogue No.:PA 28 02570

  • CAS :

    NA

  • Molecular Formula : C21H22ClFN5O2

  • Molecular Weight : 430.88

stdClass Object
(
    [pname] => 1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
    [catalogue_number] => PA 28 02580
    [category_ids] => 89,80,78,71,79
    [chemical_name] => 
    [weight] => 458.87
    [form] => C22H20ClFN4O4
    [cas] => 2223677-58-3
    [pslug] => 2223677-58-3-1-4-3-chloro-4-fluorophenyl-amino-7-s-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-5-hydroxypyrrolidin-2-one-pa2802580
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PA 28 02580

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one


  • Catalogue No.:PA 28 02580

  • CAS :

    2223677-58-3

  • Molecular Formula : C22H20ClFN4O4

  • Molecular Weight : 458.87

stdClass Object
(
    [pname] => (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide
    [catalogue_number] => PA 28 02590
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 503.95
    [form] => C24H27ClFN5O4
    [cas] => NA
    [pslug] => s-n-4-3-chloro-4-fluorophenyl-amino-7-s-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-3-hydroxybutanamide-pa2802590
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PA 28 02590

(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide


  • Catalogue No.:PA 28 02590

  • CAS :

    NA

  • Molecular Formula : C24H27ClFN5O4

  • Molecular Weight : 503.95

stdClass Object
(
    [pname] => (R)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide
    [catalogue_number] => PA 28 02600
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 503.95
    [form] => C24H27ClFN5O4
    [cas] => NA
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PA 28 02600

(R)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide


  • Catalogue No.:PA 28 02600

  • CAS :

    NA

  • Molecular Formula : C24H27ClFN5O4

  • Molecular Weight : 503.95

stdClass Object
(
    [pname] => (S,E)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 02610
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 485.94
    [form] => C24H25ClFN5O3
    [cas] => 2475094-87-0
    [pslug] => 2475094-87-0-s-e-n-4-4-chloro-3-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802610
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PA 28 02610

(S,E)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 02610

  • CAS :

    2475094-87-0

  • Molecular Formula : C24H25ClFN5O3

  • Molecular Weight : 485.94

stdClass Object
(
    [pname] => (S,E)-4-(Dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
    [catalogue_number] => PA 28 02620
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 451.49
    [form] => C24H26FN5O3
    [cas] => 2413212-25-4
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PA 28 02620

(S,E)-4-(Dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide


  • Catalogue No.:PA 28 02620

  • CAS :

    2413212-25-4

  • Molecular Formula : C24H26FN5O3

  • Molecular Weight : 451.49

stdClass Object
(
    [pname] => (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 02630
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 485.94
    [form] => C24H25ClFN5O3
    [cas] => 1680184-59-1
    [pslug] => 1680184-59-1-s-z-n-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802630
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PA 28 02630

(S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 02630

  • CAS :

    1680184-59-1

  • Molecular Formula : C24H25ClFN5O3

  • Molecular Weight : 485.94

stdClass Object
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    [pname] => (R)-Afatinib
    [catalogue_number] => PA 28 02640
    [category_ids] => 89,80,79,78,71
    [chemical_name] => 
    [weight] => 485.94
    [form] => C24H25ClFN5O3
    [cas] => 945553-91-3
    [pslug] => 945553-91-3-r-afatinib-pa2802640
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PA 28 02640

(R)-Afatinib


  • Catalogue No.:PA 28 02640

  • CAS :

    945553-91-3

  • Molecular Formula : C24H25ClFN5O3

  • Molecular Weight : 485.94

stdClass Object
(
    [pname] => (S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-amine
    [catalogue_number] => PA 28 02650
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 404.78
    [form] => C18H14ClFN4O4
    [cas] => 314771-88-5
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PA 28 02650

(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-amine


  • Catalogue No.:PA 28 02650

  • CAS :

    314771-88-5

  • Molecular Formula : C18H14ClFN4O4

  • Molecular Weight : 404.78

stdClass Object
(
    [pname] => (S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 02660
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 469.48
    [form] => C24H25F2N5O3
    [cas] => 2223677-62-9
    [pslug] => 2223677-62-9-s-e-n-4-3-4-difluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802660
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PA 28 02660

(S,E)-N-(4-((3,4-Difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 02660

  • CAS :

    2223677-62-9

  • Molecular Formula : C24H25F2N5O3

  • Molecular Weight : 469.48

stdClass Object
(
    [pname] => (S,E)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
    [catalogue_number] => PA 28 02670
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 442.87
    [form] => C22H20ClFN4O3
    [cas] => NA
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PA 28 02670

(S,E)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide


  • Catalogue No.:PA 28 02670

  • CAS :

    NA

  • Molecular Formula : C22H20ClFN4O3

  • Molecular Weight : 442.87

stdClass Object
(
    [pname] => (S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
    [catalogue_number] => PA 28 02690
    [category_ids] => 82,80,79,78,71,70
    [chemical_name] => 
    [weight] => 521.77
    [form] => C22H19BrClFN4O3
    [cas] => 1637254-93-3
    [pslug] => 1637254-93-3-s-e-4-bromo-n-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-but-2-enamide-pa2802690
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PA 28 02690

(S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide


  • Catalogue No.:PA 28 02690

  • CAS :

    1637254-93-3

  • Molecular Formula : C22H19BrClFN4O3

  • Molecular Weight : 521.77

stdClass Object
(
    [pname] => (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methylamino)but-2-enamide
    [catalogue_number] => PA 28 02710
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 471.91
    [form] => C23H23ClFN5O3
    [cas] => 2413212-13-0
    [pslug] => 2413212-13-0-s-e-n-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-methylamino-but-2-enamide-pa2802710
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PA 28 02710

(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methylamino)but-2-enamide


  • Catalogue No.:PA 28 02710

  • CAS :

    2413212-13-0

  • Molecular Formula : C23H23ClFN5O3

  • Molecular Weight : 471.91

stdClass Object
(
    [pname] => (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 02740
    [category_ids] => ,89,79,80,78,
    [chemical_name] => 
    [weight] => 429.88
    [form] => C21H21ClFN5O2
    [cas] => 1245555-42-3
    [pslug] => 1245555-42-3-e-n-4-3-chloro-4-fluorophenyl-amino-7-methoxyquinazolin-6-yl-4-dimethylamino-but-2-enamide-pa2802740
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PA 28 02740

(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 02740

  • CAS :

    1245555-42-3

  • Molecular Formula : C21H21ClFN5O2

  • Molecular Weight : 429.88

stdClass Object
(
    [pname] => (S)-N-(4-((4-Fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide
    [catalogue_number] => PA 28 02750
    [category_ids] => ,89,79,80,78,71,
    [chemical_name] => 
    [weight] => 368.36
    [form] => C19H17FN4O3
    [cas] => NA
    [pslug] => s-n-4-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-formamide-pa2802750
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PA 28 02750

(S)-N-(4-((4-Fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide


  • Catalogue No.:PA 28 02750

  • CAS :

    NA

  • Molecular Formula : C19H17FN4O3

  • Molecular Weight : 368.36

stdClass Object
(
    [pname] => N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
    [catalogue_number] => PA 28 02780
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 348.72
    [form] => C15H10ClFN4O3
    [cas] => 179552-74-0
    [pslug] => 179552-74-0-n-3-chloro-4-fluorophenyl-7-methoxy-6-nitroquinazolin-4-amine-pa2802780
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PA 28 02780

N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine


  • Catalogue No.:PA 28 02780

  • CAS :

    179552-74-0

  • Molecular Formula : C15H10ClFN4O3

  • Molecular Weight : 348.72

stdClass Object
(
    [pname] => (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
    [catalogue_number] => PA 28 02800
    [category_ids] => 79,80,89,82,78,70
    [chemical_name] => 
    [weight] => 442.87
    [form] => C22H20ClFN4O3
    [cas] => 2223677-64-1
    [pslug] => 2223677-64-1-s-e-n-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-but-2-enamide-pa2802800
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PA 28 02800

(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide


  • Catalogue No.:PA 28 02800

  • CAS :

    2223677-64-1

  • Molecular Formula : C22H20ClFN4O3

  • Molecular Weight : 442.87

stdClass Object
(
    [pname] => Afatinib-d4
    [catalogue_number] => PA STI 004270
    [category_ids] => 98,82,79,78,71,70,69
    [chemical_name] => 
    [weight] => 489.96
    [form] => C24H21D4ClFN5O3
    [cas] => NA
    [pslug] => afatinib-d4-pasti004270
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PA STI 004270

Afatinib-d4


  • Catalogue No.:PA STI 004270

  • CAS :

    NA

  • Molecular Formula : C24H21D4ClFN5O3

  • Molecular Weight : 489.96

stdClass Object
(
    [pname] => 1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-2-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
    [catalogue_number] => PA 28 02820
    [category_ids] => ,89,79,80,71,78,
    [chemical_name] => 
    [weight] => 458.87
    [form] => C22H20ClFN4O4
    [cas] => NA
    [pslug] => 1-4-3-chloro-4-fluorophenyl-amino-7-s-tetrahydrofuran-2-yl-oxy-quinazolin-6-yl-5-hydroxypyrrolidin-2-one-pa2802820
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PA 28 02820

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-2-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one


  • Catalogue No.:PA 28 02820

  • CAS :

    NA

  • Molecular Formula : C22H20ClFN4O4

  • Molecular Weight : 458.87

stdClass Object
(
    [pname] => Afatinib-d6 Dimaleate (N,N-dimethyl-d6)
    [catalogue_number] => PA STI 088303
    [category_ids] => 98,82,78,70
    [chemical_name] => 
    [weight] => 724.13
    [form] => C32H27D6ClFN5O11
    [cas] => NA
    [pslug] => afatinib-d6-dimaleate-n-n-dimethyl-d6-pasti088303
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PA STI 088303

Afatinib-d6 Dimaleate (N,N-dimethyl-d6)


  • Catalogue No.:PA STI 088303

  • CAS :

    NA

  • Molecular Formula : C32H27D6ClFN5O11

  • Molecular Weight : 724.13

stdClass Object
(
    [pname] => (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
    [catalogue_number] => PA 28 0021000
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 358.40
    [form] => C18H22N4O4
    [cas] => 1456696-14-2
    [pslug] => 1456696-14-2-2e-n-3-4-dihydro-4-oxo-7-3s-tetrahydro-3-furanyl-oxy-6-quinazolinyl-4-dimethylamino-2-butenamide-pa280021000
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PA 28 0021000

(2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide


  • Catalogue No.:PA 28 0021000

  • CAS :

    1456696-14-2

  • Molecular Formula : C18H22N4O4

  • Molecular Weight : 358.40

stdClass Object
(
    [pname] => 4-N-(3-Chloro-4-fluorophenyl)-7-[(3R)-oxolan-3-yl]oxyquinazoline-4,6-diamine
    [catalogue_number] => PA 28 0021001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 374.8
    [form] => C18H16ClFN4O2
    [cas] => 402855-03-2
    [pslug] => 402855-03-2-4-n-3-chloro-4-fluorophenyl-7-3r-oxolan-3-yl-oxyquinazoline-4-6-diamine-pa280021001
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PA 28 0021001

4-N-(3-Chloro-4-fluorophenyl)-7-[(3R)-oxolan-3-yl]oxyquinazoline-4,6-diamine


  • Catalogue No.:PA 28 0021001

  • CAS :

    402855-03-2

  • Molecular Formula : C18H16ClFN4O2

  • Molecular Weight : 374.8

stdClass Object
(
    [pname] => Afatinib Maleic acid Adduct
    [catalogue_number] => PA 28 0021002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 602.02
    [form] => C28H29ClFN5O7
    [cas] => NA
    [pslug] => afatinib-maleic-acid-adduct-pa280021002
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PA 28 0021002

Afatinib Maleic acid Adduct


  • Catalogue No.:PA 28 0021002

  • CAS :

    NA

  • Molecular Formula : C28H29ClFN5O7

  • Molecular Weight : 602.02

stdClass Object
(
    [pname] => N-(4-chloro-3-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
    [catalogue_number] => PA 28 0021003
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 336.68
    [form] => C14H7ClF2N4O2
    [cas] => 2475095-50-0
    [pslug] => 2475095-50-0-n-4-chloro-3-fluorophenyl-7-fluoro-6-nitroquinazolin-4-amine-pa280021003
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PA 28 0021003

N-(4-chloro-3-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine


  • Catalogue No.:PA 28 0021003

  • CAS :

    2475095-50-0

  • Molecular Formula : C14H7ClF2N4O2

  • Molecular Weight : 336.68

stdClass Object
(
    [pname] => 4-Dimethylaminobut-2-ynoic Acid Hydrochloride
    [catalogue_number] => PA 28 0021004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 163.6
    [form] => C6H10ClNO2
    [cas] => 118764-06-0
    [pslug] => 118764-06-0-4-dimethylaminobut-2-ynoic-acid-hydrochloride-pa280021004
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PA 28 0021004

4-Dimethylaminobut-2-ynoic Acid Hydrochloride


  • Catalogue No.:PA 28 0021004

  • CAS :

    118764-06-0

  • Molecular Formula : C6H10ClNO2

  • Molecular Weight : 163.6

stdClass Object
(
    [pname] => (R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
    [catalogue_number] => PA 28 0021005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 404.78
    [form] =>  C18H14ClFN4O4
    [cas] => 402855-07-6
    [pslug] => 402855-07-6-r-n-3-chloro-4-fluorophenyl-6-nitro-7-tetrahydrofuran-3-yl-oxy-quinazolin-4-amine-pa280021005
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PA 28 0021005

(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine


  • Catalogue No.:PA 28 0021005

  • CAS :

    402855-07-6

  • Molecular Formula : C18H14ClFN4O4

  • Molecular Weight : 404.78

stdClass Object
(
    [pname] => (S,Z)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 0021006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 502.4
    [form] => C24H25Cl2N5O3
    [cas] => NA
    [pslug] => s-z-n-4-3-4-dichlorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa280021006
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PA 28 0021006

(S,Z)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 0021006

  • CAS :

    NA

  • Molecular Formula : C24H25Cl2N5O3

  • Molecular Weight : 502.4

stdClass Object
(
    [pname] =>  (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
    [catalogue_number] => PA 28 0021007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 358.35
    [form] => C18H16F2N4O2
    [cas] => 2044709-72-8
    [pslug] => 2044709-72-8s-n4-3-4-difluorophenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa280021007
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PA 28 0021007

 (S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine


  • Catalogue No.:PA 28 0021007

  • CAS :

    2044709-72-8

  • Molecular Formula : C18H16F2N4O2

  • Molecular Weight : 358.35

stdClass Object
(
    [pname] => (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide
    [catalogue_number] => PA 28 0021008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 503.96
    [form] => C24H27ClFN5O4
    [cas] => 2413212-21-0
    [pslug] => 2413212-21-0-s-n-4-3-chloro-4-fluorophenyl-amino-7-r-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-3-hydroxybutanamide-pa280021008
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PA 28 0021008

(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide


  • Catalogue No.:PA 28 0021008

  • CAS :

    2413212-21-0

  • Molecular Formula : C24H27ClFN5O4

  • Molecular Weight : 503.96

stdClass Object
(
    [pname] => (R)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide
    [catalogue_number] => PA 28 0021009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 503.96
    [form] => C24H27ClFN5O4
    [cas] => 2413212-23-2
    [pslug] => 2413212-23-2-r-n-4-3-chloro-4-fluorophenyl-amino-7-r-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-3-hydroxybutanamide-pa280021009
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PA 28 0021009

(R)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide


  • Catalogue No.:PA 28 0021009

  • CAS :

    2413212-23-2

  • Molecular Formula : C24H27ClFN5O4

  • Molecular Weight : 503.96

stdClass Object
(
    [pname] => Diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate
    [catalogue_number] => PA 28 0021011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 552.92
    [form] => C24H27ClFN4O6P
    [cas] => 618061-76-0
    [pslug] => 618061-76-0-diethyl-s-2-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-amino-2-oxoethyl-phosphonate-pa280021011
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PA 28 0021011

Diethyl (S)-(2-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-2-oxoethyl)phosphonate


  • Catalogue No.:PA 28 0021011

  • CAS :

    618061-76-0

  • Molecular Formula : C24H27ClFN4O6P

  • Molecular Weight : 552.92

stdClass Object
(
    [pname] => 4-((4-Chloro-3-fluorophenyl)amino)-6-nitroquinazolin-7-ol
    [catalogue_number] => PA 28 0021012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 334.69
    [form] => C14H8ClFN4O3
    [cas] => 2475094-95-0
    [pslug] => 2475094-95-0-4-4-chloro-3-fluorophenyl-amino-6-nitroquinazolin-7-ol-pa280021012
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PA 28 0021012

4-((4-Chloro-3-fluorophenyl)amino)-6-nitroquinazolin-7-ol


  • Catalogue No.:PA 28 0021012

  • CAS :

    2475094-95-0

  • Molecular Formula : C14H8ClFN4O3

  • Molecular Weight : 334.69

stdClass Object
(
    [pname] => (S)-N-(4-((4-Fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide
    [catalogue_number] => PA 28 0021010
    [category_ids] => ,71,78,79,80,89,
    [chemical_name] => 
    [weight] => 368.37
    [form] => C19H17FN4O3
    [cas] => NA
    [pslug] => s-n-4-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-formamide-pa280021010
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PA 28 0021010

(S)-N-(4-((4-Fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide


  • Catalogue No.:PA 28 0021010

  • CAS :

    NA

  • Molecular Formula : C19H17FN4O3

  • Molecular Weight : 368.37

stdClass Object
(
    [pname] => N-(4-Chloro-3-fluorophenyl)-7-fluoro-8-nitroquinazolin-4-amine
    [catalogue_number] => PA 28 0021013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 336.68
    [form] => C14H7ClF2N4O2
    [cas] => 2475094-96-1
    [pslug] => 2475094-96-1-n-4-chloro-3-fluorophenyl-7-fluoro-8-nitroquinazolin-4-amine-pa280021013
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PA 28 0021013

N-(4-Chloro-3-fluorophenyl)-7-fluoro-8-nitroquinazolin-4-amine


  • Catalogue No.:PA 28 0021013

  • CAS :

    2475094-96-1

  • Molecular Formula : C14H7ClF2N4O2

  • Molecular Weight : 336.68

stdClass Object
(
    [pname] => (S,E)-N-(4-((3-Chloro-4-fluorophenyl)(nitroso)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 0021014
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 514.94
    [form] => C24H24ClFN6O4
    [cas] => NA
    [pslug] => s-e-n-4-3-chloro-4-fluorophenyl-nitroso-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa280021014
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PA 28 0021014

(S,E)-N-(4-((3-Chloro-4-fluorophenyl)(nitroso)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 0021014

  • CAS :

    NA

  • Molecular Formula : C24H24ClFN6O4

  • Molecular Weight : 514.94

stdClass Object
(
    [pname] => (S,Z)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 0021015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 485.94
    [form] => C24H25ClFN5O3
    [cas] => NA
    [pslug] => s-z-n-4-4-chloro-3-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-4-dimethylamino-but-2-enamide-pa280021015
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PA 28 0021015

(S,Z)-N-(4-((4-Chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 0021015

  • CAS :

    NA

  • Molecular Formula : C24H25ClFN5O3

  • Molecular Weight : 485.94

stdClass Object
(
    [pname] => N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
    [catalogue_number] => PA 28 0021016
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 320.23
    [form] => C14H7F3N4O2
    [cas] => 2226537-61-5
    [pslug] => 2226537-61-5-n-3-4-difluorophenyl-7-fluoro-6-nitroquinazolin-4-amine-pa280021016
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PA 28 0021016

N-(3,4-Difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine


  • Catalogue No.:PA 28 0021016

  • CAS :

    2226537-61-5

  • Molecular Formula : C14H7F3N4O2

  • Molecular Weight : 320.23

stdClass Object
(
    [pname] => 4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol
    [catalogue_number] => PA 28 0021017
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 334.69
    [form] => C14H8ClFN4O3
    [cas] => 1449430-45-8
    [pslug] => 1449430-45-8-4-3-chloro-4-fluorophenyl-amino-6-nitroquinazolin-7-ol-pa280021017
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PA 28 0021017

4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol


  • Catalogue No.:PA 28 0021017

  • CAS :

    1449430-45-8

  • Molecular Formula : C14H8ClFN4O3

  • Molecular Weight : 334.69

stdClass Object
(
    [pname] => (S)-N4-(3,4-Dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
    [catalogue_number] => PA 28 0021018
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 391.25
    [form] => C18H16Cl2N4O2
    [cas] => 2044709-79-5
    [pslug] => 2044709-79-5-s-n4-3-4-dichlorophenyl-7-tetrahydrofuran-3-yl-oxy-quinazoline-4-6-diamine-pa280021018
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PA 28 0021018

(S)-N4-(3,4-Dichlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine


  • Catalogue No.:PA 28 0021018

  • CAS :

    2044709-79-5

  • Molecular Formula : C18H16Cl2N4O2

  • Molecular Weight : 391.25

stdClass Object
(
    [pname] => 1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
    [catalogue_number] => PA 28 0021019
    [category_ids] => ,75,78,70,82,
    [chemical_name] => 
    [weight] => 458.87
    [form] => C22H20ClFN4O4
    [cas] => 2413212-19-6
    [pslug] => 2413212-19-6-1-4-3-chloro-4-fluorophenyl-amino-7-r-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-5-hydroxypyrrolidin-2-one-pa280021019
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PA 28 0021019

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((R)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one


  • Catalogue No.:PA 28 0021019

  • CAS :

    2413212-19-6

  • Molecular Formula : C22H20ClFN4O4

  • Molecular Weight : 458.87

stdClass Object
(
    [pname] => 3-(2-Pyridyl)-5,6-bis(4-sulfophenyl)-1,2,4-trazine Disodium Salt Hydrate
    [catalogue_number] => PA 28 0021020
    [category_ids] => ,75,76,79,69,71,78,82,
    [chemical_name] => 
    [weight] => 534.47
    [form] => C20H16N4Na2O7S2
    [cas] => 1083240-27-0
    [pslug] => 1083240-27-0-3-2-pyridyl-5-6-bis-4-sulfophenyl-1-2-4-trazine-disodium-salt-hydrate-pa280021020
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PA 28 0021020

3-(2-Pyridyl)-5,6-bis(4-sulfophenyl)-1,2,4-trazine Disodium Salt Hydrate


  • Catalogue No.:PA 28 0021020

  • CAS :

    1083240-27-0

  • Molecular Formula : C20H16N4Na2O7S2

  • Molecular Weight : 534.47

stdClass Object
(
    [pname] => N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-3,4-bis(dimethylamino)butanamide
    [catalogue_number] => PA 28 0021021
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 531.03
    [form] => C26H32ClFN6O3
    [cas] => 2414260-31-2
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PA 28 0021021

N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-3,4-bis(dimethylamino)butanamide


  • Catalogue No.:PA 28 0021021

  • CAS :

    2414260-31-2

  • Molecular Formula : C26H32ClFN6O3

  • Molecular Weight : 531.03

stdClass Object
(
    [pname] => (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide
    [catalogue_number] => PA 28 0021022
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 415.85
    [form] => C20H19ClFN5O2
    [cas] => 2223677-61-8
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PA 28 0021022

(E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-hydroxyquinazolin-6-yl)-4-(dimethylamino)but-2-enamide


  • Catalogue No.:PA 28 0021022

  • CAS :

    2223677-61-8

  • Molecular Formula : C20H19ClFN5O2

  • Molecular Weight : 415.85

stdClass Object
(
    [pname] => N1,N2-Bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)oxalamide
    [catalogue_number] => PA 28 0021023
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 803.6
    [form] => C38H30Cl2F2N8O6
    [cas] => 2223677-65-2
    [pslug] => 2223677-65-2-n1-n2-bis-4-3-chloro-4-fluorophenyl-amino-7-s-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-oxalamide-pa280021023
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PA 28 0021023

N1,N2-Bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)oxalamide


  • Catalogue No.:PA 28 0021023

  • CAS :

    2223677-65-2

  • Molecular Formula : C38H30Cl2F2N8O6

  • Molecular Weight : 803.6

stdClass Object
(
    [pname] => (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide
    [catalogue_number] => PA 28 0021024
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 473.89
    [form] => C22H21ClFN5O4
    [cas] => 2223677-66-3
    [pslug] => 2223677-66-3-s-n1-4-3-chloro-4-fluorophenyl-amino-7-tetrahydrofuran-3-yl-oxy-quinazolin-6-yl-n2-n2-dimethyloxalamide-pa280021024
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PA 28 0021024

(S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide


  • Catalogue No.:PA 28 0021024

  • CAS :

    2223677-66-3

  • Molecular Formula : C22H21ClFN5O4

  • Molecular Weight : 473.89

stdClass Object
(
    [pname] => Afatinib N-Oxide
    [catalogue_number] => PA 28 0021025
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 501.94
    [form] => C24H25ClFN5O4
    [cas] => 2413212-11-8
    [pslug] => 2413212-11-8-afatinib-n-oxide-pa280021025
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PA 28 0021025

Afatinib N-Oxide


  • Catalogue No.:PA 28 0021025

  • CAS :

    2413212-11-8

  • Molecular Formula : C24H25ClFN5O4

  • Molecular Weight : 501.94