Avapritinib
Avapritinib, sold under the brand name Ayvakit. it is a selective tyrosine kinase inhibitor being investigated for the treatment of multidrug resistant gastrointestinal tumors. Reference standards of Avapritinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Avapritinib
[catalogue_number] => PA 01 3920000
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 498.57
[form] => C26H27FN10
[cas] => 1703793-34-3
[pslug] => 1703793-34-3-avapritinib-api-standards-pa013920000
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Catalogue No.:PA 01 3920000
Molecular Formula : C26H27FN10
Molecular Weight : 498.57
stdClass Object
(
[pname] => 4-(4-(5-(1-(4-Fluorophenyl)vinyl)pyrimidin-2-yl)piperazin-1-yl)-6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazine
[catalogue_number] => PA 01 3921000
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 481.54
[form] => C26H24FN9
[cas] => 1703793-09-2
[pslug] => 1703793-09-2-4-4-5-1-4-fluorophenyl-vinyl-pyrimidin-2-yl-piperazin-1-yl-6-1-methyl-1h-pyrazol-4-yl-pyrrolo-2-1-f-1-2-4-triazine-pa013921000
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4-(4-(5-(1-(4-Fluorophenyl)vinyl)pyrimidin-2-yl)piperazin-1-yl)-6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazine
Catalogue No.:PA 01 3921000
Molecular Formula : C26H24FN9
Molecular Weight : 481.54
stdClass Object
(
[pname] => (S)-1-(2-(4-(6-Bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)-1-(4-fluorophenyl)ethan-1-amine
[catalogue_number] => PA 01 3921001
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 497.38
[form] => C22H22BrFN8
[cas] => 2505078-30-6
[pslug] => 2505078-30-6-s-1-2-4-6-bromopyrrolo-2-1-f-1-2-4-triazin-4-yl-piperazin-1-yl-pyrimidin-5-yl-1-4-fluorophenyl-ethan-1-amine-pa013921001
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(S)-1-(2-(4-(6-Bromopyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)-1-(4-fluorophenyl)ethan-1-amine
Catalogue No.:PA 01 3921001
Molecular Formula : C22H22BrFN8
Molecular Weight : 497.38
stdClass Object
(
[pname] => (R)-1-(4-Fluorophenyl)-1-(2-(piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine
[catalogue_number] => PA 01 3921002
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 301.37
[form] => C16H20FN5
[cas] => 1704492-16-9
[pslug] => 1704492-16-9-r-1-4-fluorophenyl-1-2-piperazin-1-yl-pyrimidin-5-yl-ethan-1-amine-pa013921002
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(R)-1-(4-Fluorophenyl)-1-(2-(piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine
Catalogue No.:PA 01 3921002
Molecular Formula : C16H20FN5
Molecular Weight : 301.37
stdClass Object
(
[pname] => R-Avapritinib
[catalogue_number] => PA 01 3921003
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 498.57
[form] => C26H27FN10
[cas] => 1703793-32-1
[pslug] => 1703793-32-1-r-avapritinib-pa013921003
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Catalogue No.:PA 01 3921003
Molecular Formula : C26H27FN10
Molecular Weight : 498.57
