carfilzomib

Pharmaceutical standards - Carfilzomib is derived from epoxomicin, a natural product that was shown by the laboratory of Craig Crews at Yale University to inhibit the proteasome. It is an anti-cancer drug acting as a selective proteasome inhibitor. Chemically, it is a tetrapeptide epoxyketone and an analog of epoxomicin.. Reference standards of Carfilzomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => (S)-N-Methoxy-N,4-dimethyl-2-((S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanamido)pentanamide
    [catalogue_number] => PA 30 0631074
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 722.93
    [form] => C39H58N6O7
    [cas] => NA
    [pslug] => s-n-methoxy-n-4-dimethyl-2-s-2-s-4-methyl-2-s-2-2-morpholinoacetamido-4-phenylbutanamido-pentanamido-3-phenylpropanamido-pentanamide-pa300631074
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PA 30 0631074
PA 30 0631074

(S)-N-Methoxy-N,4-dimethyl-2-((S)-2-((S)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanamido)pentanamide

  • Catalogue No.:PA 30 0631074

  • CAS :

    NA

  • Molecular Formula : C39H58N6O7

  • Molecular Weight : 722.93

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Details 
stdClass Object
(
    [pname] => (R)-4-Methyl-N-((S)-1-(((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631075
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
    [pslug] => r-4-methyl-n-s-1-r-4-methyl-1-s-2-methyloxiran-2-yl-1-oxopentan-2-yl-amino-1-oxo-3-phenylpropan-2-yl-2-r-2-2-morpholinoacetamido-4-phenylbutanamido-pentanamide-pa300631075
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PA 30 0631075
PA 30 0631075

(R)-4-Methyl-N-((S)-1-(((R)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

  • Catalogue No.:PA 30 0631075

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

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Details 
stdClass Object
(
    [pname] => (S)-2-Amino-N-methoxy-N,4-dimethylpentanamide
    [catalogue_number] => PA 30 0631076
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 174.24
    [form] => C8H18N2O2
    [cas] => 102837-29-6
    [pslug] => 102837-29-6-s-2-amino-n-methoxy-n-4-dimethylpentanamide-pa300631076
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PA 30 0631076
PA 30 0631076

(S)-2-Amino-N-methoxy-N,4-dimethylpentanamide

  • Catalogue No.:PA 30 0631076

  • CAS :

    102837-29-6

  • Molecular Formula : C8H18N2O2

  • Molecular Weight : 174.24

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Details 
stdClass Object
(
    [pname] => 4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide
    [catalogue_number] => PA 30 0631077
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 739.91
    [form] => C39H57N5O9
    [cas] => NA
    [pslug] => 4-methyl-2-2-2-morpholinoacetamido-4-phenylbutanamido-n-1-oxo-3-phenyl-1-1-2-2-trihydroxy-6-methyl-3-oxoheptan-4-yl-amino-propan-2-yl-pentanamide-pa300631077
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PA 30 0631077
PA 30 0631077

4-Methyl-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)-N-(1-oxo-3-phenyl-1-((1,2,2-trihydroxy-6-methyl-3-oxoheptan-4-yl)amino)propan-2-yl)pentanamide

  • Catalogue No.:PA 30 0631077

  • CAS :

    NA

  • Molecular Formula : C39H57N5O9

  • Molecular Weight : 739.91

Enquire
Details 
stdClass Object
(
    [pname] => 4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide
    [catalogue_number] => PA 30 0631078
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 719.92
    [form] => C40H57N5O7
    [cas] => NA
    [pslug] => 4-methyl-n-1-4-methyl-1-2-methyloxiran-2-yl-1-oxopentan-2-yl-amino-1-oxo-3-phenylpropan-2-yl-2-2-2-morpholinoacetamido-4-phenylbutanamido-pentanamide-pa300631078
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PA 30 0631078
PA 30 0631078

4-Methyl-N-(1-((4-methyl-1-(2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-(2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide

  • Catalogue No.:PA 30 0631078

  • CAS :

    NA

  • Molecular Formula : C40H57N5O7

  • Molecular Weight : 719.92

Enquire
Details 
stdClass Object
(
    [pname] => ((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid
    [catalogue_number] => PA 30 0631079
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 394.42
    [form] => C19H26N2O7
    [cas] => NA
    [pslug] => s-2-tert-butoxycarbonyl-amino-4-phenylbutanoyl-l-aspartic-acid-pa300631079
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PA 30 0631079
PA 30 0631079

((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanoyl)-L-aspartic Acid

  • Catalogue No.:PA 30 0631079

  • CAS :

    NA

  • Molecular Formula : C19H26N2O7

  • Molecular Weight : 394.42

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Details 
stdClass Object
(
    [pname] => 2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid
    [catalogue_number] => PA 30 0631080
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 276.29
    [form] => C14H16N2O4
    [cas] => NA
    [pslug] => 2-2s-5s-3-6-dioxo-5-phenethylpiperazin-2-yl-acetic-acid-pa300631080
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PA 30 0631080
PA 30 0631080

2-((2S,5S)-3,6-Dioxo-5-phenethylpiperazin-2-yl)acetic Acid

  • Catalogue No.:PA 30 0631080

  • CAS :

    NA

  • Molecular Formula : C14H16N2O4

  • Molecular Weight : 276.29

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Details 
stdClass Object
(
    [pname] => ((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid
    [catalogue_number] => PA 30 0631081
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 294.31
    [form] => C14H18N2O5
    [cas] => 3066865-52-6
    [pslug] => 3066865-52-6-s-2-amino-4-phenylbutanoyl-l-aspartic-acid-pa300631081
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PA 30 0631081
PA 30 0631081

((S)-2-Amino-4-phenylbutanoyl)-L-aspartic Acid

  • Catalogue No.:PA 30 0631081

  • CAS :

    3066865-52-6

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

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Details 
stdClass Object
(
    [pname] => N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine
    [catalogue_number] => PA 30 0631082
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 294.31
    [form] => C14H18N2O5
    [cas] => NA
    [pslug] => n4-s-1-carboxy-3-phenylpropyl-l-asparagine-pa300631082
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PA 30 0631082
PA 30 0631082

N4-((S)-1-carboxy-3-phenylpropyl)-L-asparagine

  • Catalogue No.:PA 30 0631082

  • CAS :

    NA

  • Molecular Formula : C14H18N2O5

  • Molecular Weight : 294.31

Enquire
Details 
stdClass Object
(
    [pname] => (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid
    [catalogue_number] => PA 30 0631083
    [category_ids] => ,82,80,78,71,70,
    [chemical_name] => 
    [weight] => 440.54
    [form] => C25H32N2O5
    [cas] => NA
    [pslug] => s-2-s-2-tert-butoxycarbonyl-amino-4-phenylbutanamido-4-phenylbutanoic-acid-pa300631083
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PA 30 0631083
PA 30 0631083

(S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-4-phenylbutanamido)-4-phenylbutanoic Acid

  • Catalogue No.:PA 30 0631083

  • CAS :

    NA

  • Molecular Formula : C25H32N2O5

  • Molecular Weight : 440.54

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Details
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