ivacaftor
Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Ivacaftor
[catalogue_number] => PA 09 40000
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 392.49
[form] => C24H28N2O3
[cas] => 873054-44-5
[pslug] => 873054-44-5-ivacaftor-api-pa0940000
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Catalogue No.:PA 09 40000
Molecular Formula : C24H28N2O3
Molecular Weight : 392.49
stdClass Object
(
[pname] => 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid
[catalogue_number] => PA 09 40510
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 189.17
[form] => C10H7NO3
[cas] => 13721-01-2
[pslug] => 13721-01-2-4-oxo-1-4-dihydroquinoline-3-carboxylic-acid-pa0940510
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4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid
Catalogue No.:PA 09 40510
Molecular Formula : C10H7NO3
Molecular Weight : 189.17
stdClass Object
(
[pname] => 1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
[catalogue_number] => PA 09 40520
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 217.22
[form] => C12H11NO3
[cas] => 52980-28-6
[pslug] => 52980-28-6-1-4-dihydro-4-oxo-3-quinolinecarboxylic-acid-ethyl-ester-pa0940520
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1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
Catalogue No.:PA 09 40520
Molecular Formula : C12H11NO3
Molecular Weight : 217.22
stdClass Object
(
[pname] => diethyl 2-((phenylamino)methylene)malonate
[catalogue_number] => PA 09 0401000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 263.29
[form] => C14H17NO4
[cas] => 54535-22-7
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diethyl 2-((phenylamino)methylene)malonate
Catalogue No.:PA 09 0401000
Molecular Formula : C14H17NO4
Molecular Weight : 263.29
stdClass Object
(
[pname] => De-Alkylated Ivacaftor
[catalogue_number] => PA 09 0401001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 336.39
[form] => C20H20N2O3
[cas] => 873054-39-8
[pslug] => 873054-39-8-de-alkylated-ivacaftor-pa090401001
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Catalogue No.:PA 09 0401001
Molecular Formula : C20H20N2O3
Molecular Weight : 336.39
stdClass Object
(
[pname] => Ivacaftor D4
[catalogue_number] => PA STI 089107
[category_ids] => ,98,75,76,78,70,82,
[chemical_name] =>
[weight] => 396.52
[form] => C24H24D4N2O3
[cas] => NA
[pslug] => ivacaftor-d4-pasti089107
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Catalogue No.:PA STI 089107
Molecular Formula : C24H24D4N2O3
Molecular Weight : 396.52
stdClass Object
(
[pname] => 4-Hydroxyquinoline-3-carboxylic Acid
[catalogue_number] => PA 09 0401002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 189.17
[form] => C10H7NO3
[cas] => 34785-11-0
[pslug] => 34785-11-0-4-hydroxyquinoline-3-carboxylic-acid-pa090401002
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4-Hydroxyquinoline-3-carboxylic Acid
Catalogue No.:PA 09 0401002
Molecular Formula : C10H7NO3
Molecular Weight : 189.17
stdClass Object
(
[pname] => Ivacaftor D18
[catalogue_number] => PA STI 089190
[category_ids] => ,98,75,76,78,70,82,
[chemical_name] =>
[weight] => 410.61
[form] => C24H10D18N2O3
[cas] => 1413431-05-6
[pslug] => 1413431-05-6-ivacaftor-d18-pasti089190
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Catalogue No.:PA STI 089190
Molecular Formula : C24H10D18N2O3
Molecular Weight : 410.61
stdClass Object
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[pname] => 2,4-Di-tert-butyl-6-nitrophenol
[catalogue_number] => PA 09 0401003
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 251.33
[form] => C14H21NO3
[cas] => 20039-94-5
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2,4-Di-tert-butyl-6-nitrophenol
Catalogue No.:PA 09 0401003
Molecular Formula : C14H21NO3
Molecular Weight : 251.33
stdClass Object
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[pname] => 4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid
[catalogue_number] => PA 09 0401004
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 492.57
[form] => C28H32N2O6
[cas] => NA
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4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid
Catalogue No.:PA 09 0401004
Molecular Formula : C28H32N2O6
Molecular Weight : 492.57
stdClass Object
(
[pname] => 1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
[catalogue_number] => PA 09 0401005
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[chemical_name] =>
[weight] => 218.17
[form] => C10H6N2O4
[cas] => NA
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1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
Catalogue No.:PA 09 0401005
Molecular Formula : C10H6N2O4
Molecular Weight : 218.17
stdClass Object
(
[pname] => 2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
[catalogue_number] => PA 09 0401006
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 563.65
[form] => C34H33N3O5
[cas] => 2760759-55-3
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2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
Catalogue No.:PA 09 0401006
Molecular Formula : C34H33N3O5
Molecular Weight : 563.65
stdClass Object
(
[pname] => N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide
[catalogue_number] => PA 09 0401007
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 365.39
[form] => C20H19N3O4
[cas] => NA
[pslug] => n-4-tert-butyl-3-hydroxyphenyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401007
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N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide
Catalogue No.:PA 09 0401007
Molecular Formula : C20H19N3O4
Molecular Weight : 365.39
stdClass Object
(
[pname] => Ivacaftor Nitroso Impurity
[catalogue_number] => PA 09 0401008
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 421.5
[form] => C24H27N3O4
[cas] => NA
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Ivacaftor Nitroso Impurity
stdClass Object
(
[pname] => 5-Amino-2,4-di-tert-butylphenyl methyl carbonate
[catalogue_number] => PA 09 0401009
[category_ids] => ,80,78,82,
[chemical_name] =>
[weight] => 279.38
[form] => C16H25NO3
[cas] => 1182822-31-6
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5-Amino-2,4-di-tert-butylphenyl methyl carbonate
Catalogue No.:PA 09 0401009
Molecular Formula : C16H25NO3
Molecular Weight : 279.38
stdClass Object
(
[pname] => N-Nitroso Ivacaftor Ortho Isomer
[catalogue_number] => PA 09 0401010
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 421.5
[form] => C24H27N3O4
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N-Nitroso Ivacaftor Ortho Isomer
stdClass Object
(
[pname] => Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate
[catalogue_number] => PA 09 0401011
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 246.22
[form] => C12H10N2O4
[cas] => NA
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Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate
Catalogue No.:PA 09 0401011
Molecular Formula : C12H10N2O4
Molecular Weight : 246.22
stdClass Object
(
[pname] => 2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate
[catalogue_number] => PA 09 0401012
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 309.36
[form] => C16H23NO5
[cas] => 873055-56-2
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2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate
Catalogue No.:PA 09 0401012
Molecular Formula : C16H23NO5
Molecular Weight : 309.36
stdClass Object
(
[pname] => Diethyl 2-((nitroso(phenyl)amino)methylene)malonate
[catalogue_number] => PA 09 0401013
[category_ids] => ,78,70,82,162,
[chemical_name] =>
[weight] => 292.29
[form] => C14H16N2O5
[cas] => NA
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Diethyl 2-((nitroso(phenyl)amino)methylene)malonate
Catalogue No.:PA 09 0401013
Molecular Formula : C14H16N2O5
Molecular Weight : 292.29
stdClass Object
(
[pname] => N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
[catalogue_number] => PA 09 0401014
[category_ids] => ,70,78,80,82,162,
[chemical_name] =>
[weight] => 421.5
[form] => C24H27N3O4
[cas] => NA
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N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
stdClass Object
(
[pname] => Ivacaftor Amine Impurity
[catalogue_number] => PA 09 0401015
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 392.5
[form] => C24H28N2O3
[cas] => 2760759-58-6
[pslug] => 2760759-58-6-ivacaftor-amine-impurity-pa090401015
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stdClass Object
(
[pname] => 2-(Aminomethyl)-3,5-di-tert-butylphenol
[catalogue_number] => PA 09 0401016
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 235.37
[form] => C15H25NO
[cas] => 84210-35-5
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2-(Aminomethyl)-3,5-di-tert-butylphenol
Catalogue No.:PA 09 0401016
Molecular Formula : C15H25NO
Molecular Weight : 235.37
stdClass Object
(
[pname] => N-(4-(tert-Butyl)-3,6-dioxocyclohexa-1,4-dien-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
[catalogue_number] => PA 09 0401017
[category_ids] => ,80,78,70,82,
[chemical_name] =>
[weight] => 350.37
[form] => C20H18N2O4
[cas] => NA
[pslug] => n-4-tert-butyl-3-6-dioxocyclohexa-1-4-dien-1-yl-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401017
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N-(4-(tert-Butyl)-3,6-dioxocyclohexa-1,4-dien-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
Catalogue No.:PA 09 0401017
Molecular Formula : C20H18N2O4
Molecular Weight : 350.37
stdClass Object
(
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[catalogue_number] => PA 09 0401018
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[weight] => 422.48
[form] => C24H26N2O5
[cas] => 2760759-57-5
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2,4-Di-tert-butyl-5-nitrophenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
Catalogue No.:PA 09 0401018
Molecular Formula : C24H26N2O5
Molecular Weight : 422.48
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[pname] => 4-Oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide
[catalogue_number] => PA 09 0401019
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[weight] => 264.28
[form] => C16H12N2O2
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[pslug] => 325779-54-2-4-oxo-n-phenyl-1-4-dihydroquinoline-3-carboxamide-pa090401019
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4-Oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide
Catalogue No.:PA 09 0401019
Molecular Formula : C16H12N2O2
Molecular Weight : 264.28
