nintedanib

Pharmaceutical standards - A Nintedanib is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer. It is a small molecule kinase inhibitor. Reference standards of Nintedanib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (Z)-1-Acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid
    [catalogue_number] => PA 14 0541076
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 351.36
    [form] => C20H17NO5
    [cas] => 1985659-44-6
    [pslug] => 1985659-44-6-z-1-acetyl-3-ethoxy-phenyl-methylene-2-oxoindoline-6-carboxylic-acid-pa140541076
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PA 14 0541076
PA 14 0541076

(Z)-1-Acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylic Acid

  • Catalogue No.:PA 14 0541076

  • CAS :

    1985659-44-6

  • Molecular Formula : C20H17NO5

  • Molecular Weight : 351.36

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Details 
stdClass Object
(
    [pname] => Methyl (Z)-1-acetyl-3-(2-methoxybenzylidene)-2-oxoindoline-6-carboxylate
    [catalogue_number] => PA 14 0541077
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 351.36
    [form] => C20H17NO5
    [cas] => NA
    [pslug] => methyl-z-1-acetyl-3-2-methoxybenzylidene-2-oxoindoline-6-carboxylate-pa140541077
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PA 14 0541077
PA 14 0541077

Methyl (Z)-1-acetyl-3-(2-methoxybenzylidene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541077

  • CAS :

    NA

  • Molecular Formula : C20H17NO5

  • Molecular Weight : 351.36

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Details 
stdClass Object
(
    [pname] => Ethyl (Z)-1-acetyl-3-(2-ethoxybenzylidene)-2-oxoindoline-6-carboxylate
    [catalogue_number] => PA 14 0541078
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 379.41
    [form] => C22H21NO5
    [cas] => NA
    [pslug] => ethyl-z-1-acetyl-3-2-ethoxybenzylidene-2-oxoindoline-6-carboxylate-pa140541078
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PA 14 0541078
PA 14 0541078

Ethyl (Z)-1-acetyl-3-(2-ethoxybenzylidene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541078

  • CAS :

    NA

  • Molecular Formula : C22H21NO5

  • Molecular Weight : 379.41

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Details 
stdClass Object
(
    [pname] => N-(4-Aminophenyl)-2-(4-(2-((4-aminophenyl)amino)-2-oxoethyl)piperazin-1-yl)-N-methylacetamide
    [catalogue_number] => PA 14 0541079
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 396.50
    [form] => C21H28N6O2
    [cas] => NA
    [pslug] => n-4-aminophenyl-2-4-2-4-aminophenyl-amino-2-oxoethyl-piperazin-1-yl-n-methylacetamide-pa140541079
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PA 14 0541079
PA 14 0541079

N-(4-Aminophenyl)-2-(4-(2-((4-aminophenyl)amino)-2-oxoethyl)piperazin-1-yl)-N-methylacetamide

  • Catalogue No.:PA 14 0541079

  • CAS :

    NA

  • Molecular Formula : C21H28N6O2

  • Molecular Weight : 396.50

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Details 
stdClass Object
(
    [pname] => Methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
    [catalogue_number] => PA 14 0541067
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 553.66
    [form] => C32H35N5O4
    [cas] => NA
    [pslug] => methyl-z-3-4-2-4-ethylpiperazin-1-yl-n-methylacetamido-phenyl-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541067
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PA 14 0541067
PA 14 0541067

Methyl (Z)-3-(((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541067

  • CAS :

    NA

  • Molecular Formula : C32H35N5O4

  • Molecular Weight : 553.66

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Details 
stdClass Object
(
    [pname] => (Z)-2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoacetic Acid
    [catalogue_number] => PA 14 0541080
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 471.47
    [form] => C26H21N3O6
    [cas] => NA
    [pslug] => z-2-4-6-methoxycarbonyl-2-oxoindolin-3-ylidene-phenyl-methyl-amino-phenyl-methyl-amino-2-oxoacetic-acid-pa140541080
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PA 14 0541080
PA 14 0541080

(Z)-2-((4-(((6-(Methoxycarbonyl)-2-oxoindolin-3-ylidene)(phenyl)methyl)amino)phenyl)(methyl)amino)-2-oxoacetic Acid

  • Catalogue No.:PA 14 0541080

  • CAS :

    NA

  • Molecular Formula : C26H21N3O6

  • Molecular Weight : 471.47

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Details 
stdClass Object
(
    [pname] => N-Methyl-N-(4-nitrophenyl)nitrous amide
    [catalogue_number] => PA 14 0541081
    [category_ids] => ,79,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 181.15
    [form] => C7H7N3O3
    [cas] => NA
    [pslug] => n-methyl-n-4-nitrophenyl-nitrous-amide-pa140541081
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PA 14 0541081
PA 14 0541081

N-Methyl-N-(4-nitrophenyl)nitrous amide

  • Catalogue No.:PA 14 0541081

  • CAS :

    NA

  • Molecular Formula : C7H7N3O3

  • Molecular Weight : 181.15

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Details 
stdClass Object
(
    [pname] => Methyl (Z)-3-(2-((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)benzylidene)-2-oxoindoline-6-carboxylate
    [catalogue_number] => PA 14 0541082
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 553.66
    [form] => C32H35N5O4
    [cas] => NA
    [pslug] => methyl-z-3-2-4-2-4-ethylpiperazin-1-yl-n-methylacetamido-phenyl-amino-benzylidene-2-oxoindoline-6-carboxylate-pa140541082
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PA 14 0541082
PA 14 0541082

Methyl (Z)-3-(2-((4-(2-(4-ethylpiperazin-1-yl)-N-methylacetamido)phenyl)amino)benzylidene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541082

  • CAS :

    NA

  • Molecular Formula : C32H35N5O4

  • Molecular Weight : 553.66

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Details 
stdClass Object
(
    [pname] => Methyl (E)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
    [catalogue_number] => PA 14 0541083
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 525.61
    [form] => C30H31N5O4
    [cas] => NA
    [pslug] => methyl-e-3-4-2-4-methylpiperazin-1-yl-acetamido-phenyl-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541083
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PA 14 0541083
PA 14 0541083

Methyl (E)-3-(((4-(2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541083

  • CAS :

    NA

  • Molecular Formula : C30H31N5O4

  • Molecular Weight : 525.61

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Details 
stdClass Object
(
    [pname] => Methyl (Z)-3-(((4-(methyl(nitroso)amino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
    [catalogue_number] => PA 14 0541084
    [category_ids] => ,79,71,78,70,82,162,
    [chemical_name] => 
    [weight] => 428.45
    [form] => C24H20N4O4
    [cas] => NA
    [pslug] => methyl-z-3-4-methyl-nitroso-amino-phenyl-amino-phenyl-methylene-2-oxoindoline-6-carboxylate-pa140541084
    [latest_product] => 0
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PA 14 0541084
PA 14 0541084

Methyl (Z)-3-(((4-(methyl(nitroso)amino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

  • Catalogue No.:PA 14 0541084

  • CAS :

    NA

  • Molecular Formula : C24H20N4O4

  • Molecular Weight : 428.45

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Details 
stdClass Object
(
    [pname] => N-(4-Aminophenyl)-N-methyl-2-(piperazin-1-yl)acetamide Hydrochloride
    [catalogue_number] => PA 14 0541085
    [category_ids] => ,79,71,78,70,82,
    [chemical_name] => 
    [weight] => 284.79
    [form] => C13H21ClN4O
    [cas] => NA
    [pslug] => n-4-aminophenyl-n-methyl-2-piperazin-1-yl-acetamide-hydrochloride-pa140541085
    [latest_product] => 0
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PA 14 0541085
PA 14 0541085

N-(4-Aminophenyl)-N-methyl-2-(piperazin-1-yl)acetamide Hydrochloride

  • Catalogue No.:PA 14 0541085

  • CAS :

    NA

  • Molecular Formula : C13H21ClN4O

  • Molecular Weight : 284.79

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