palbociclib

Pharmaceutical standards - Palbociclib is a drug which is used to treat a certain type of breast cancer. Palbociclib was the first CDK4/6 inhibitor to be approved as a cancer therapy.Reference standards of Palbociclib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => 3-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-(octadecyloxy)-4-oxobutanoic Acid
    [catalogue_number] => PA 43 0061075
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 816.1
    [form] => C46H69N7O6
    [cas] => NA
    [pslug] => 3-4-6-6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7-8-dihydropyrido-2-3-d-pyrimidin-2-yl-amino-pyridin-3-yl-piperazin-1-yl-4-octadecyloxy-4-oxobutanoic-acid-pa430061075
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PA 43 0061075
PA 43 0061075

3-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-(octadecyloxy)-4-oxobutanoic Acid

  • Catalogue No.:PA 43 0061075

  • CAS :

    NA

  • Molecular Formula : C46H69N7O6

  • Molecular Weight : 816.1

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Details 
stdClass Object
(
    [pname] => 5-(4-Nitrosopiperazin-1-yl)pyridin-2-ol
    [catalogue_number] => PA 43 0061078
    [category_ids] => ,79,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 208.22
    [form] => C9H12N4O2
    [cas] => NA
    [pslug] => 5-4-nitrosopiperazin-1-yl-pyridin-2-ol-pa430061078
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PA 43 0061078
PA 43 0061078

5-(4-Nitrosopiperazin-1-yl)pyridin-2-ol

  • Catalogue No.:PA 43 0061078

  • CAS :

    NA

  • Molecular Formula : C9H12N4O2

  • Molecular Weight : 208.22

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Details 
stdClass Object
(
    [pname] => tert-Butyl 4-(6-((8-cyclopentyl-6-(1-isobutoxyvinyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
    [catalogue_number] => PA 43 0061079
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 603.77
    [form] => C33H45N7O4
    [cas] => NA
    [pslug] => tert-butyl-4-6-8-cyclopentyl-6-1-isobutoxyvinyl-5-methyl-7-oxo-7-8-dihydropyrido-2-3-d-pyrimidin-2-yl-amino-pyridin-3-yl-piperazine-1-carboxylate-pa430061079
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PA 43 0061079
PA 43 0061079

tert-Butyl 4-(6-((8-cyclopentyl-6-(1-isobutoxyvinyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate

  • Catalogue No.:PA 43 0061079

  • CAS :

    NA

  • Molecular Formula : C33H45N7O4

  • Molecular Weight : 603.77

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Details 
stdClass Object
(
    [pname] => 2-Acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061080
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 447.54
    [form] => C24H29N7O2
    [cas] => 2204442-50-0
    [pslug] => 2204442-50-0-2-acetyl-8-cyclopentyl-5-methyl-6-5-piperazin-1-yl-pyridin-2-yl-amino-pyrido-2-3-d-pyrimidin-7-8h-one-pa430061080
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PA 43 0061080
PA 43 0061080

2-Acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061080

  • CAS :

    2204442-50-0

  • Molecular Formula : C24H29N7O2

  • Molecular Weight : 447.54

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Details 
stdClass Object
(
    [pname] => 6-Acetyl-2-((5-((2-aminoethyl)amino)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 2,2,2-trifluoroacetate
    [catalogue_number] => PA 43 0061081
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 535.53
    [form] => C24H28F3N7O4
    [cas] => NA
    [pslug] => 6-acetyl-2-5-2-aminoethyl-amino-pyridin-2-yl-amino-8-cyclopentyl-5-methylpyrido-2-3-d-pyrimidin-7-8h-one-2-2-2-trifluoroacetate-pa430061081
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PA 43 0061081
PA 43 0061081

6-Acetyl-2-((5-((2-aminoethyl)amino)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one 2,2,2-trifluoroacetate

  • Catalogue No.:PA 43 0061081

  • CAS :

    NA

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  • Molecular Weight : 535.53

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stdClass Object
(
    [pname] => N-(6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)-N-(5-(4-formylpiperazin-1-yl)pyridin-2-yl)nitrous amide
    [catalogue_number] => PA 43 0061082
    [category_ids] => ,79,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 504.55
    [form] => C25H28N8O4
    [cas] => NA
    [pslug] => n-6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7-8-dihydropyrido-2-3-d-pyrimidin-2-yl-n-5-4-formylpiperazin-1-yl-pyridin-2-yl-nitrous-amide-pa430061082
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PA 43 0061082
PA 43 0061082

N-(6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)-N-(5-(4-formylpiperazin-1-yl)pyridin-2-yl)nitrous amide

  • Catalogue No.:PA 43 0061082

  • CAS :

    NA

  • Molecular Formula : C25H28N8O4

  • Molecular Weight : 504.55

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Details 
stdClass Object
(
    [pname] => (E)-1,2-bis(5-(4-Methylpiperazin-1-yl)pyridin-2-yl)diazene
    [catalogue_number] => PA 43 0061084
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 380.5
    [form] => C20H28N8
    [cas] => NA
    [pslug] => e-1-2-bis-5-4-methylpiperazin-1-yl-pyridin-2-yl-diazene-pa430061084
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PA 43 0061084
PA 43 0061084

(E)-1,2-bis(5-(4-Methylpiperazin-1-yl)pyridin-2-yl)diazene

  • Catalogue No.:PA 43 0061084

  • CAS :

    NA

  • Molecular Formula : C20H28N8

  • Molecular Weight : 380.5

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Details 
stdClass Object
(
    [pname] => 3-(2-Chloro-4-(cyclopentyl(nitroso)amino)pyrimidin-5-yl)but-2-enoic Acid
    [catalogue_number] => PA 43 0061083
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 310.74
    [form] => C13H15ClN4O3
    [cas] => NA
    [pslug] => 3-2-chloro-4-cyclopentyl-nitroso-amino-pyrimidin-5-yl-but-2-enoic-acid-pa430061083
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PA 43 0061083
PA 43 0061083

3-(2-Chloro-4-(cyclopentyl(nitroso)amino)pyrimidin-5-yl)but-2-enoic Acid

  • Catalogue No.:PA 43 0061083

  • CAS :

    NA

  • Molecular Formula : C13H15ClN4O3

  • Molecular Weight : 310.74

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Details 
stdClass Object
(
    [pname] => 6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061085
    [category_ids] => ,79,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 532.65
    [form] => C28H36N8O3
    [cas] => NA
    [pslug] => 6-1-butoxyvinyl-8-cyclopentyl-5-methyl-2-5-4-nitrosopiperazin-1-yl-pyridin-2-yl-amino-pyrido-2-3-d-pyrimidin-7-8h-one-pa430061085
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PA 43 0061085
PA 43 0061085

6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061085

  • CAS :

    NA

  • Molecular Formula : C28H36N8O3

  • Molecular Weight : 532.65

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Details 
stdClass Object
(
    [pname] => 6-Desacetyl Palbociclib Hydrochloride
    [catalogue_number] => PA 43 0061086
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 441.96
    [form] => C22H28ClN7O
    [cas] => NA
    [pslug] => 6-desacetyl-palbociclib-hydrochloride-pa430061086
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PA 43 0061086
PA 43 0061086

6-Desacetyl Palbociclib Hydrochloride

  • Catalogue No.:PA 43 0061086

  • CAS :

    NA

  • Molecular Formula : C22H28ClN7O

  • Molecular Weight : 441.96

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stdClass Object
(
    [pname] => 6-Desacetyl-6-Bromo Palbociclib Hydrochloride
    [catalogue_number] => PA 43 0061087
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 520.86
    [form] => C22H27BrClN7O
    [cas] => NA
    [pslug] => 6-desacetyl-6-bromo-palbociclib-hydrochloride-pa430061087
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PA 43 0061087
PA 43 0061087

6-Desacetyl-6-Bromo Palbociclib Hydrochloride

  • Catalogue No.:PA 43 0061087

  • CAS :

    NA

  • Molecular Formula : C22H27BrClN7O

  • Molecular Weight : 520.86

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stdClass Object
(
    [pname] => 5-Bromo-N2,N4-dicyclopentylpyrimidine-2,4-diamine
    [catalogue_number] => PA 43 0061088
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 325.25
    [form] => C14H21BrN4
    [cas] => NA
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PA 43 0061088
PA 43 0061088

5-Bromo-N2,N4-dicyclopentylpyrimidine-2,4-diamine

  • Catalogue No.:PA 43 0061088

  • CAS :

    NA

  • Molecular Formula : C14H21BrN4

  • Molecular Weight : 325.25

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Details 
stdClass Object
(
    [pname] => 6-Acetyl-8-cyclopentyl-2-(cyclopentylamino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061089
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 354.45
    [form] =>  C20H26N4O2
    [cas] => NA
    [pslug] => 6-acetyl-8-cyclopentyl-2-cyclopentylamino-5-methylpyrido-2-3-d-pyrimidin-7-8h-one-pa430061089
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PA 43 0061089
PA 43 0061089

6-Acetyl-8-cyclopentyl-2-(cyclopentylamino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061089

  • CAS :

    NA

  • Molecular Formula : C20H26N4O2

  • Molecular Weight : 354.45

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Details 
stdClass Object
(
    [pname] => Desoxo-Palbociclib Hydrochloride
    [catalogue_number] => PA 43 0061090
    [category_ids] => ,79,80,71,81,78,70,82,75,
    [chemical_name] => 
    [weight] => 468
    [form] => C24H30ClN7O
    [cas] => NA
    [pslug] => desoxo-palbociclib-hydrochloride-pa430061090
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PA 43 0061090
PA 43 0061090

Desoxo-Palbociclib Hydrochloride

  • Catalogue No.:PA 43 0061090

  • CAS :

    NA

  • Molecular Formula : C24H30ClN7O

  • Molecular Weight : 468

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stdClass Object
(
    [pname] => 6-Acetyl-8-(2-hydroxycyclopentyl)-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061091
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 463.54
    [form] => C24H29N7O3
    [cas] => NA
    [pslug] => 6-acetyl-8-2-hydroxycyclopentyl-5-methyl-2-5-piperazin-1-yl-pyridin-2-yl-amino-pyrido-2-3-d-pyrimidin-7-8h-one-pa430061091
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PA 43 0061091
PA 43 0061091

6-Acetyl-8-(2-hydroxycyclopentyl)-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061091

  • CAS :

    NA

  • Molecular Formula : C24H29N7O3

  • Molecular Weight : 463.54

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Details 
stdClass Object
(
    [pname] => 6-Acetyl-8-(3-hydroxycyclopentyl)-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061092
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 463.54
    [form] => C24H29N7O3
    [cas] => NA
    [pslug] => 6-acetyl-8-3-hydroxycyclopentyl-5-methyl-2-5-piperazin-1-yl-pyridin-2-yl-amino-pyrido-2-3-d-pyrimidin-7-8h-one-pa430061092
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PA 43 0061092
PA 43 0061092

6-Acetyl-8-(3-hydroxycyclopentyl)-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061092

  • CAS :

    NA

  • Molecular Formula : C24H29N7O3

  • Molecular Weight : 463.54

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Details 
stdClass Object
(
    [pname] => 6-Acetyl-8-cyclopentyl-2-((5-(4-hydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061093
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 463.54
    [form] => C24H29N7O3
    [cas] => NA
    [pslug] => 6-acetyl-8-cyclopentyl-2-5-4-hydroxypiperazin-1-yl-pyridin-2-yl-amino-5-methylpyrido-2-3-d-pyrimidin-7-8h-one-pa430061093
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PA 43 0061093
PA 43 0061093

6-Acetyl-8-cyclopentyl-2-((5-(4-hydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061093

  • CAS :

    NA

  • Molecular Formula : C24H29N7O3

  • Molecular Weight : 463.54

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Details 
stdClass Object
(
    [pname] => 6-Acetyl-8-cyclopentyl-2-((5-(2,6-dihydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061094
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 479.54
    [form] => C24H29N7O4
    [cas] => NA
    [pslug] => 6-acetyl-8-cyclopentyl-2-5-2-6-dihydroxypiperazin-1-yl-pyridin-2-yl-amino-5-methylpyrido-2-3-d-pyrimidin-7-8h-one-pa430061094
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PA 43 0061094
PA 43 0061094

6-Acetyl-8-cyclopentyl-2-((5-(2,6-dihydroxypiperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061094

  • CAS :

    NA

  • Molecular Formula : C24H29N7O4

  • Molecular Weight : 479.54

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Details 
stdClass Object
(
    [pname] => 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(2-oxopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061095
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 461.53
    [form] => C24H27N7O3
    [cas] => NA
    [pslug] => 6-acetyl-8-cyclopentyl-5-methyl-2-5-2-oxopiperazin-1-yl-pyridin-2-yl-amino-pyrido-2-3-d-pyrimidin-7-8h-one-pa430061095
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PA 43 0061095
PA 43 0061095

6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(2-oxopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061095

  • CAS :

    NA

  • Molecular Formula : C24H27N7O3

  • Molecular Weight : 461.53

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Details 
stdClass Object
(
    [pname] => 8-Cyclopentyl-5-methyl-7-oxo-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic Acid
    [catalogue_number] => PA 43 0061096
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 449.52
    [form] => C23H27N7O3
    [cas] => NA
    [pslug] => 8-cyclopentyl-5-methyl-7-oxo-2-5-piperazin-1-yl-pyridin-2-yl-amino-7-8-dihydropyrido-2-3-d-pyrimidine-6-carboxylic-acid-pa430061096
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PA 43 0061096
PA 43 0061096

8-Cyclopentyl-5-methyl-7-oxo-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic Acid

  • Catalogue No.:PA 43 0061096

  • CAS :

    NA

  • Molecular Formula : C23H27N7O3

  • Molecular Weight : 449.52

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Details 
stdClass Object
(
    [pname] => 8-Cyclopentyl-6-hydroxy-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
    [catalogue_number] => PA 43 0061097
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 421.51
    [form] => C22H27N7O2
    [cas] => NA
    [pslug] => 8-cyclopentyl-6-hydroxy-5-methyl-2-5-piperazin-1-yl-pyridin-2-yl-amino-pyrido-2-3-d-pyrimidin-7-8h-one-pa430061097
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PA 43 0061097
PA 43 0061097

8-Cyclopentyl-6-hydroxy-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one

  • Catalogue No.:PA 43 0061097

  • CAS :

    NA

  • Molecular Formula : C22H27N7O2

  • Molecular Weight : 421.51

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Details 
stdClass Object
(
    [pname] => 2-((8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide
    [catalogue_number] => PA 43 0061098
    [category_ids] => ,79,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 421.51
    [form] => C22H27N7O2
    [cas] => 2488840-56-6
    [pslug] => 2488840-56-6-2-8-cyclopentyl-5-methyl-7-oxo-7-8-dihydropyrido-2-3-d-pyrimidin-2-yl-amino-5-piperazin-1-yl-pyridine-1-oxide-pa430061098
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PA 43 0061098
PA 43 0061098

2-((8-Cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide

  • Catalogue No.:PA 43 0061098

  • CAS :

    2488840-56-6

  • Molecular Formula : C22H27N7O2

  • Molecular Weight : 421.51

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