Roflumilast is used in the prevention of lung attacks in severe COPD. It is a long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).Reference standards of Roflumilast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Roflumilast - API Standards [catalogue_number] => PA 18 15000 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 403.21 [form] => C17H14Cl2F2N2O3 [cas] => 162401-32-3 [pslug] => 162401-32-3-roflumilast-api-standards-pa1815000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15000
CAS :
Molecular Formula : C17H14Cl2F2N2O3
Molecular Weight : 403.21
stdClass Object ( [pname] => 5-Dechloro Roflumilast [catalogue_number] => PA 18 15510 [category_ids] => ,71,75,81,78,70,82, [chemical_name] => [weight] => 368.76 [form] => C17H15ClF2N2O3 [cas] => 1391053-75-0 [pslug] => 1391053-75-0-5-dechloro-roflumilast-pa1815510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15510
Molecular Formula : C17H15ClF2N2O3
Molecular Weight : 368.76
stdClass Object ( [pname] => 3-O-Decyclopropyl Roflumilast [catalogue_number] => PA 18 15520 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 349.12 [form] => C13H8Cl2F2N2O3 [cas] => 1391052-76-8 [pslug] => 1391052-76-8-3-o-decyclopropyl-roflumilast-pa1815520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15520
Molecular Formula : C13H8Cl2F2N2O3
Molecular Weight : 349.12
stdClass Object ( [pname] => Roflumilast N-Oxide [catalogue_number] => PA 18 15530 [category_ids] => 82,81,78,76,75,71,70 [chemical_name] => [weight] => 419.21 [form] => C17H14Cl2F2N2O4 [cas] => 292135-78-5 [pslug] => 292135-78-5-roflumilast-n-oxide-pa1815530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15530
Molecular Formula : C17H14Cl2F2N2O4
Molecular Weight : 419.21
stdClass Object ( [pname] => 4-Amino-3,5-dichloropyridine [catalogue_number] => PA 18 15550 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 163 [form] => C5H4Cl2N2 [cas] => 22889-78-7 [pslug] => 22889-78-7-4-amino-3-5-dichloropyridine-pa1815550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15550
Molecular Formula : C5H4Cl2N2
Molecular Weight : 163
stdClass Object ( [pname] => 3-(Cyclobutoxy-N-(3,5-dichloropyridin-4-yl))-4-(difluoromethoxy)benzamide [catalogue_number] => PA 18 15560 [category_ids] => 81,82,78,70 [chemical_name] => [weight] => 403.21 [form] => C17H14Cl2F2N2O3 [cas] => 2368178-28-1 [pslug] => 2368178-28-1-3-cyclobutoxy-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-benzamide-pa1815560 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15560
stdClass Object ( [pname] => 3,4-Di(cyclopropylmethoxy) Roflumilast [catalogue_number] => PA 18 15570 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 407.29 [form] => C20H20Cl2N2O3 [cas] => 1391052-24-6 [pslug] => 1391052-24-6-3-4-di-cyclopropylmethoxy-roflumilast-pa1815570 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15570
Molecular Formula : C20H20Cl2N2O3
Molecular Weight : 407.29
stdClass Object ( [pname] => 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast [catalogue_number] => PA 18 15580 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 403.21 [form] => C17H14Cl2F2N2O3 [cas] => 162401-43-6 [pslug] => 162401-43-6-4-cyclopropylmethoxy-3-difluoromethoxy-roflumilast-pa1815580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15580
stdClass Object ( [pname] => 3,4-bis(Difluoromethoxy) Roflumilast [catalogue_number] => PA 18 15590 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 399.12 [form] => C14H8Cl2F4N2O3 [cas] => 162401-30-1 [pslug] => 162401-30-1-3-4-bis-difluoromethoxy-roflumilast-pa1815590 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15590
Molecular Formula : C14H8Cl2F4N2O3
Molecular Weight : 399.12
stdClass Object ( [pname] => N-(3,5-Dichloro-4-pyridinyl)-3,4-Dihydroxybenzamide [catalogue_number] => PA 18 15600 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 299.11 [form] => C12H8Cl2N2O3 [cas] => 1412448-29-3 [pslug] => 1412448-29-3-n-3-5-dichloro-4-pyridinyl-3-4-dihydroxybenzamide-pa1815600 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15600
Molecular Formula : C12H8Cl2N2O3
Molecular Weight : 299.11
stdClass Object ( [pname] => 3-Cyclobutyl-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide [catalogue_number] => PA 18 15610 [category_ids] => ,80,71,75,81,78,70,82, [chemical_name] => [weight] => 387.21 [form] => C17H14Cl2F2N2O2 [cas] => NA [pslug] => 3-cyclobutyl-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-benzamide-pa1815610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15610
Molecular Formula : C17H14Cl2F2N2O2
Molecular Weight : 387.21
stdClass Object ( [pname] => 3-(But-3-en-1-yloxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide [catalogue_number] => PA 18 15620 [category_ids] => 80,71,75,70,78,82,81 [chemical_name] => [weight] => 403.21 [form] => C17H14Cl2F2N2O3 [cas] => 2368178-29-2 [pslug] => 3-but-3-en-1-yloxy-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-benzamide-pa1815620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15620
stdClass Object ( [pname] => 3,4-Di(cyclopropylmethoxy)-benzoic Acid [catalogue_number] => PA 18 15630 [category_ids] => 82,78,70,71,80 [chemical_name] => [weight] => 262.3 [form] => C15H18O4 [cas] => 1369851-30-8 [pslug] => 1369851-30-8-3-4-di-cyclopropylmethoxy-benzoic-acid-pa1815630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15630
Molecular Formula : C15H18O4
Molecular Weight : 262.3
stdClass Object ( [pname] => Roflumilast-d4 [catalogue_number] => PA STI 078300 [category_ids] => ,81,98,78,70,82, [chemical_name] => [weight] => 407.23 [form] => C17H11D3Cl2F2N2O3 [cas] => 1398065-69-4 [pslug] => 1398065-69-4-roflumilast-d4-pasti078300 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 078300
Molecular Formula : C17H11D3Cl2F2N2O3
Molecular Weight : 407.23
stdClass Object ( [pname] => Roflumilast-d4 N-Oxide [catalogue_number] => PA STI 078310 [category_ids] => ,71,98,76,75,81,78,70,82, [chemical_name] => [weight] => 423.23 [form] => C17H10D4Cl2F2N2O4 [cas] => 1794760-31-8 [pslug] => 1794760-31-8-roflumilast-d4-n-oxide-pasti078310 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 078310
Molecular Formula : C17H10D4Cl2F2N2O4
Molecular Weight : 423.23
stdClass Object ( [pname] => 2,3-Dichloropyridin-4-amine [catalogue_number] => PA 18 15670 [category_ids] => ,82,75,78,70,82, [chemical_name] => [weight] => 163 [form] => C5H4Cl2N2 [cas] => 184416-83-9 [pslug] => 184416-83-9-2-3-dichloropyridin-4-amine-pa1815670 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 15670
stdClass Object ( [pname] => 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide [catalogue_number] => PA 18 0151000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 353.2 [form] => C16H14Cl2N2O3 [cas] => 475271-62-6 [pslug] => 475271-62-6-3-cyclopropylmethoxy-n-3-5-dichloropyridin-4-yl-4-hydroxybenzamide-pa180151000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151000
Molecular Formula : C16H14Cl2N2O3
Molecular Weight : 353.2
stdClass Object ( [pname] => N-(3-Bromo-5-chloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide [catalogue_number] => PA 18 0151001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 447.66 [form] => C17H14BrClF2N2O3 [cas] => NA [pslug] => n-3-bromo-5-chloropyridin-4-yl-3-cyclopropylmethoxy-4-difluoromethoxy-benzamide-pa180151001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151001
Molecular Formula : C17H14BrClF2N2O3
Molecular Weight : 447.66
stdClass Object ( [pname] => 5-((3,5-Dichloropyridin-4-yl)carbamoyl)-2-(difluoromethoxy)phenyl dimethylcarbamate [catalogue_number] => PA 18 0151002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 420.19 [form] => C16H13Cl2F2N3O4 [cas] => 2048860-65-5 [pslug] => 2048860-65-5-5-3-5-dichloropyridin-4-yl-carbamoyl-2-difluoromethoxy-phenyl-dimethylcarbamate-pa180151002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151002
Molecular Formula : C16H13Cl2F2N3O4
Molecular Weight : 420.19
stdClass Object ( [pname] => 4-(Difluoromethoxy)-3-Hydroxybenzoic Acid [catalogue_number] => PA 18 0151003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 204.13 [form] => C8H6F2O4 [cas] => 913985-07-6 [pslug] => 913985-07-6-4-difluoromethoxy-3-hydroxybenzoic-acid-pa180151003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151003
Molecular Formula : C8H6F2O4
Molecular Weight : 204.13
stdClass Object ( [pname] => Roflumilast KSM-II Bromo Compound [catalogue_number] => PA 18 0151004 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 207.46 [form] => C5H4BrClN2 [cas] => 159783-78-5 [pslug] => 159783-78-5-roflumilast-ksm-ii-bromo-compound-pa180151004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151004
Molecular Formula : C5H4BrClN2
Molecular Weight : 207.46
stdClass Object ( [pname] => Roflumilast Dimer [catalogue_number] => PA 18 0151005 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 643.41 [form] => C29H24Cl2F4N2O6 [cas] => 1352122-37-2 [pslug] => 1352122-37-2-roflumilast-dimer-pa180151005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151005
Molecular Formula : C29H24Cl2F4N2O6
Molecular Weight : 643.41
stdClass Object ( [pname] => 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde [catalogue_number] => PA 18 0151006 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 192.21 [form] => C11H12O3 [cas] => 25934-52-5 [pslug] => 25934-52-5-3-cyclopropylmethoxy-4-hydroxybenzaldehyde-pa180151006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151006
Molecular Formula : C11H12O3
Molecular Weight : 192.21
stdClass Object ( [pname] => 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde [catalogue_number] => PA 18 0151007 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 242.22 [form] => C12H12F2O3 [cas] => 151103-09-2 [pslug] => 151103-09-2-3-cyclopropylmethoxy-4-difluoromethoxy-benzaldehyde-pa180151007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151007
Molecular Formula : C12H12F2O3
Molecular Weight : 242.22
stdClass Object ( [pname] => 3-(Cyclopropylmethoxy)-4-hydroxybenzoic Acid [catalogue_number] => PA 18 0151008 [category_ids] => ,81,78,70,82, [chemical_name] => [weight] => 208.21 [form] => C11H12O4 [cas] => 1243391-44-7 [pslug] => 1243391-44-7-3-cyclopropylmethoxy-4-hydroxybenzoic-acid-pa180151008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 18 0151008
Molecular Formula : C11H12O4
Molecular Weight : 208.21
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