Roxadustat
Pharmaceutical standards
- Roxadustat (INN, trade name Evrenzo in Japan) is an anti-anemia drug. it is a medication used for the treatment of anemia associated with chronic kidney disease (CKD) in dialysis patients. Reference standards of Roxadustat API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Roxadustat
[catalogue_number] => PA 18 1260000
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[weight] => 352.35
[form] => C19H16N2O5
[cas] => 808118-40-3
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Catalogue No.:PA 18 1260000
Molecular Formula : C19H16N2O5
Molecular Weight : 352.35
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[pname] => (1a-Methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carbonyl)glycine
[catalogue_number] => PA 18 1261000
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[weight] => 352.35
[form] => C19H16N2O5
[cas] => 2301113-15-3
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(1a-Methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carbonyl)glycine
Catalogue No.:PA 18 1261000
Molecular Formula : C19H16N2O5
Molecular Weight : 352.35
stdClass Object
(
[pname] => (4-Hydroxy-1-methyl-7-phenoxy-5,6,7,8-tetrahydroisoquinoline-3-carbonyl)glycine
[catalogue_number] => PA 18 1261001
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[chemical_name] =>
[weight] => 356.38
[form] => C19H20N2O5
[cas] => NA
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(4-Hydroxy-1-methyl-7-phenoxy-5,6,7,8-tetrahydroisoquinoline-3-carbonyl)glycine
Catalogue No.:PA 18 1261001
Molecular Formula : C19H20N2O5
Molecular Weight : 356.38
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(
[pname] => 4-Phenoxyphthalic Acid
[catalogue_number] => PA 18 1261002
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[chemical_name] =>
[weight] => 258.23
[form] => C14H10O5
[cas] => 37951-15-8
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Catalogue No.:PA 18 1261002
Molecular Formula : C14H10O5
Molecular Weight : 258.23
stdClass Object
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[pname] => 2-(Butoxycarbonyl)-5-phenoxybenzoic Acid
[catalogue_number] => PA 18 1261003
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[chemical_name] =>
[weight] => 314.34
[form] => C18H18O5
[cas] => NA
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2-(Butoxycarbonyl)-5-phenoxybenzoic Acid
Catalogue No.:PA 18 1261003
Molecular Formula : C18H18O5
Molecular Weight : 314.34
stdClass Object
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[pname] => Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
[catalogue_number] => PA 18 1261004
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[chemical_name] =>
[weight] => 309.32
[form] => C18H15NO4
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Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261004
Molecular Formula : C18H15NO4
Molecular Weight : 309.32
stdClass Object
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[catalogue_number] => PA 18 1261005
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[chemical_name] =>
[weight] => 295.29
[form] => C17H13NO4
[cas] => 1421312-35-7
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4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic Acid
Catalogue No.:PA 18 1261005
Molecular Formula : C17H13NO4
Molecular Weight : 295.29
stdClass Object
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[catalogue_number] => PA 18 1261006
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[weight] => 409.4
[form] => C21H19N3O6
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[2-[(4-Hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)- amino]-acetylamino]-acetic Acid
stdClass Object
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[catalogue_number] => PA 18 1261007
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[weight] => 368.35
[form] => C19H16N2O6
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[(4-Hydroxy-1-hydroxymethyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic Acid
Catalogue No.:PA 18 1261007
Molecular Formula : C19H16N2O6
Molecular Weight : 368.35
stdClass Object
(
[pname] => Roxadustat Methyl Ester Impurity
[catalogue_number] => PA 18 1261008
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[weight] => 366.37
[form] => C20H18N2O5
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Roxadustat Methyl Ester Impurity
Catalogue No.:PA 18 1261008
Molecular Formula : C20H18N2O5
Molecular Weight : 366.37
stdClass Object
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[catalogue_number] => PA 18 1261009
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[weight] => 311.29
[form] => C17H13NO5
[cas] => 1421312-32-4
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Methyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261009
Molecular Formula : C17H13NO5
Molecular Weight : 311.29
stdClass Object
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[catalogue_number] => PA 18 1261010
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[weight] => 339.35
[form] => C19H17NO5
[cas] => 2244489-57-2
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Isopropyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261010
Molecular Formula : C19H17NO5
Molecular Weight : 339.35
stdClass Object
(
[pname] => Butyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
[catalogue_number] => PA 18 1261011
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[weight] => 353.37
[form] => C20H19NO5
[cas] => 808115-51-7
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Butyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261011
Molecular Formula : C20H19NO5
Molecular Weight : 353.37
stdClass Object
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[catalogue_number] => PA 18 1261012
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[chemical_name] =>
[weight] => 409.44
[form] => C23H23NO6
[cas] => 2342600-60-4
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Ethyl 5-(2-(butoxycarbonyl)-4-phenoxyphenyl)oxazole-4-carboxylate
Catalogue No.:PA 18 1261012
Molecular Formula : C23H23NO6
Molecular Weight : 409.44
stdClass Object
(
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[catalogue_number] => PA 18 1261013
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 329.74
[form] => C17H12ClNO4
[cas] => 1421312-33-5
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Methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261013
Molecular Formula : C17H12ClNO4
Molecular Weight : 329.74
stdClass Object
(
[pname] => Isopropyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
[catalogue_number] => PA 18 1261014
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 357.79
[form] => C19H16ClNO4
[cas] => 2244489-60-7
[pslug] => 2244489-60-7-isopropyl-1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate-pa181261014
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Isopropyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261014
Molecular Formula : C19H16ClNO4
Molecular Weight : 357.79
stdClass Object
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[catalogue_number] => PA 18 1261015
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 351.4
[form] => C21H21NO4
[cas] => 808116-09-8
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Butyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
stdClass Object
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[catalogue_number] => PA 18 1261016
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 309.32
[form] => C18H15NO4
[cas] => 808116-52-1
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Ethyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261016
Molecular Formula : C18H15NO4
Molecular Weight : 309.32
stdClass Object
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[catalogue_number] => PA 18 1261017
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[chemical_name] =>
[weight] => 337.38
[form] => C20H19NO4
[cas] => 1809286-38-1
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Isopropyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261017
Molecular Formula : C20H19NO4
Molecular Weight : 337.38
stdClass Object
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[catalogue_number] => PA 18 1261018
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[weight] => 366.37
[form] => C20H18N2O5
[cas] => 1455089-22-1
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3-(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)propanoic Acid
Catalogue No.:PA 18 1261018
Molecular Formula : C20H18N2O5
Molecular Weight : 366.37
stdClass Object
(
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[catalogue_number] => PA 18 1261019
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[chemical_name] =>
[weight] => 297.27
[form] => C16H11NO5
[cas] => 2342600-70-6
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4-Hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylic Acid
Catalogue No.:PA 18 1261019
Molecular Formula : C16H11NO5
Molecular Weight : 297.27
stdClass Object
(
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[catalogue_number] => PA 18 1261020
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 240.26
[form] => C15H12O3
[cas] => 2088935-10-6
[pslug] => 2088935-10-6-3-methyl-5-phenoxyisobenzofuran-1-3h-one-pa181261020
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3-Methyl-5-phenoxyisobenzofuran-1(3H)-one
Catalogue No.:PA 18 1261020
Molecular Formula : C15H12O3
Molecular Weight : 240.26
stdClass Object
(
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[catalogue_number] => PA 18 1261021
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[weight] => 323.35
[form] => C19H17NO4
[cas] => 1809286-36-9
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Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
Catalogue No.:PA 18 1261021
Molecular Formula : C19H17NO4
Molecular Weight : 323.35
stdClass Object
(
[pname] => 3-Methylene-5-phenoxyisobenzofuran-1(3H)-one
[catalogue_number] => PA 18 1261022
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 238.24
[form] => C15H10O3
[cas] => NA
[pslug] => 3-methylene-5-phenoxyisobenzofuran-1-3h-one-pa181261022
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3-Methylene-5-phenoxyisobenzofuran-1(3H)-one
Catalogue No.:PA 18 1261022
Molecular Formula : C15H10O3
Molecular Weight : 238.24
stdClass Object
(
[pname] => Roxadustat Desmethyl Impurity
[catalogue_number] => PA 18 1261023
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 338.32
[form] => C18H14N2O5
[cas] => 708263-68-7
[pslug] => 708263-68-7-roxadustat-desmethyl-impurity-pa181261023
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Roxadustat Desmethyl Impurity
Catalogue No.:PA 18 1261023
Molecular Formula : C18H14N2O5
Molecular Weight : 338.32
stdClass Object
(
[pname] => 4-Hydroxy-1-methyl-N-(3-(2-oxoazepan-1-yl)propyl)-7-phenoxyisoquinoline-3-carboxamide
[catalogue_number] => PA 18 1261024
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 447.54
[form] => C26H29N3O4
[cas] => NA
[pslug] => 4-hydroxy-1-methyl-n-3-2-oxoazepan-1-yl-propyl-7-phenoxyisoquinoline-3-carboxamide-pa181261024
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4-Hydroxy-1-methyl-N-(3-(2-oxoazepan-1-yl)propyl)-7-phenoxyisoquinoline-3-carboxamide
Catalogue No.:PA 18 1261024
Molecular Formula : C26H29N3O4
Molecular Weight : 447.54
stdClass Object
(
[pname] => 2,4,4,5,5-Pentamethyl-1,3,2-dioxaborolane
[catalogue_number] => PA 18 1261025
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 142.01
[form] => C7H15BO2
[cas] => 94242-85-0
[pslug] => 94242-85-0-2-4-4-5-5-pentamethyl-1-3-2-dioxaborolane-pa181261025
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2,4,4,5,5-Pentamethyl-1,3,2-dioxaborolane
Catalogue No.:PA 18 1261025
Molecular Formula : C7H15BO2
Molecular Weight : 142.01
