An antihypertensive drug, Sacubitril is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide.Reference standards of Sacubitril API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-isopropoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate [catalogue_number] => PA 19 0661076 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 889.11 [form] => C50H60CaN2O10 [cas] => 2984580-05-2 [pslug] => 2984580-05-2-calcium-4-2s-4r-1-1-1-biphenyl-4-yl-5-isopropoxy-4-methyl-5-oxopentan-2-yl-amino-4-oxobutanoate-pa190661076 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661076
CAS :
Molecular Formula : C50H60CaN2O10
Molecular Weight : 889.11
stdClass Object ( [pname] => rel-4-((3R,5S)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic Acid [catalogue_number] => PA 19 0661077 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 365.43 [form] => C22H23NO4 [cas] => 2216746-87-9 [pslug] => 2216746-87-9-rel-4-3r-5s-5-1-1-biphenyl-4-ylmethyl-3-methyl-2-oxopyrrolidin-1-yl-4-oxobutanoic-acid-pa190661077 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661077
Molecular Formula : C22H23NO4
Molecular Weight : 365.43
stdClass Object ( [pname] => Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate [catalogue_number] => PA 19 0661078 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 439.55 [form] => C26H33NO5 [cas] => 2376611-98-0 [pslug] => 2376611-98-0-ethyl-2r-4s-5-1-1-biphenyl-4-yl-4-4-ethoxy-4-oxobutanamido-2-methylpentanoate-pa190661078 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661078
Molecular Formula : C26H33NO5
Molecular Weight : 439.55
stdClass Object ( [pname] => Cyclohexane, (2-bromoethoxy) [catalogue_number] => PA 19 0661079 [category_ids] => ,171,80,75,70,82,78, [chemical_name] => [weight] => 207.11 [form] => C8H15BrO [cas] => 131665-94-6 [pslug] => 131665-94-6-cyclohexane-2-bromoethoxy-pa190661079 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661079
Molecular Formula : C8H15BrO
Molecular Weight : 207.11
stdClass Object ( [pname] => (R)-2-Amino-3-(4-iodophenyl)propan-1-ol [catalogue_number] => PA 19 0661080 [category_ids] => ,80,75,70,82,78, [chemical_name] => [weight] => 277.11 [form] => C9H12INO [cas] => 210554-97-5 [pslug] => 210554-97-5-r-2-amino-3-4-iodophenyl-propan-1-ol-pa190661080 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661080
Molecular Formula : C9H12INO
Molecular Weight : 277.11
stdClass Object ( [pname] => tert-Butyl (R)-(1-hydroxy-3-(4-iodophenyl)propan-2-yl)carbamate [catalogue_number] => PA 19 0661081 [category_ids] => ,80,75,70,82,78, [chemical_name] => [weight] => 377.22 [form] => C14H20INO3 [cas] => 210962-92-8 [pslug] => 210962-92-8-tert-butyl-r-1-hydroxy-3-4-iodophenyl-propan-2-yl-carbamate-pa190661081 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661081
Molecular Formula : C14H20INO3
Molecular Weight : 377.22
stdClass Object ( [pname] => 5-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-5-oxopentanoic Acid [catalogue_number] => PA 19 0661082 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 425.53 [form] => C25H31NO5 [cas] => 773820-89-6 [pslug] => 773820-89-6-5-2s-4r-1-1-1-biphenyl-4-yl-5-ethoxy-4-methyl-5-oxopentan-2-yl-amino-5-oxopentanoic-acid-pa190661082 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661082
Molecular Formula : C25H31NO5
Molecular Weight : 425.53
stdClass Object ( [pname] => Methyl 4-([1,1'-biphenyl]-4-yl)-3-oxobutanoate [catalogue_number] => PA 19 0661083 [category_ids] => ,80,75,70,82,78, [chemical_name] => [weight] => 268.31 [form] => C17H16O3 [cas] => 100160-75-6 [pslug] => 100160-75-6-methyl-4-1-1-biphenyl-4-yl-3-oxobutanoate-pa190661083 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661083
Molecular Formula : C17H16O3
Molecular Weight : 268.31
stdClass Object ( [pname] => 5-([1,1'-Biphenyl]-4-yl)-2-methylene-4-oxopentanoic Acid [catalogue_number] => PA 19 0661084 [category_ids] => ,80,75,70,82,78, [chemical_name] => [weight] => 280.32 [form] => C18H16O3 [cas] => 2454675-99-9 [pslug] => 2454675-99-9-5-1-1-biphenyl-4-yl-2-methylene-4-oxopentanoic-acid-pa190661084 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 19 0661084
Molecular Formula : C18H16O3
Molecular Weight : 280.32
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