Tezacaftor
Tezacaftor is used to treat cystic fibrosis in certain people. It is a drug that is sold as a fixed-dose combination with ivacaftor as Symdeko.Reference standards of Tezacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Tezacaftor - API Standards
[catalogue_number] => PA 47 98000
[category_ids] => ,80,79,78,70,82,89,
[chemical_name] =>
[weight] => 520.51
[form] => C26H27F3N2O6
[cas] => 1152311-62-0
[pslug] => 1152311-62-0-tezacaftor-api-pa4798000
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Tezacaftor - API Standards
Catalogue No.:PA 47 98000
Molecular Formula : C26H27F3N2O6
Molecular Weight : 520.51
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[pname] => 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(8-fluoro-2-hydroxy-4-(hydroxymethyl)-1,1-dimethyl-1,2,4,5-tetrahydro-[1,4]oxazepino[4,5-a]indol-9-yl)cyclopropane-1-carboxamide
[catalogue_number] => PA 47 0981000
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 518.49
[form] => C26H25F3N2O6
[cas] => 1432657-04-9
[pslug] => 1432657-04-9-1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-n-8-fluoro-2-hydroxy-4-hydroxymethyl-1-1-dimethyl-1-2-4-5-tetrahydro-1-4-oxazepino-4-5-a-indol-9-yl-cyclopropane-1-carboxamide-pa470981000
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1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(8-fluoro-2-hydroxy-4-(hydroxymethyl)-1,1-dimethyl-1,2,4,5-tetrahydro-[1,4]oxazepino[4,5-a]indol-9-yl)cyclopropane-1-carboxamide
Catalogue No.:PA 47 0981000
Molecular Formula : C26H25F3N2O6
Molecular Weight : 518.49
stdClass Object
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[pname] => (R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
[catalogue_number] => PA 47 0981001
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 476.59
[form] => C29H33FN2O3
[cas] => 1294504-67-8
[pslug] => 1294504-67-8-r-1-5-amino-2-1-benzyloxy-2-methylpropan-2-yl-6-fluoro-1h-indol-1-yl-3-benzyloxy-propan-2-ol-pa470981001
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(R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
Catalogue No.:PA 47 0981001
Molecular Formula : C29H33FN2O3
Molecular Weight : 476.59
stdClass Object
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[pname] => (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
[catalogue_number] => PA 47 0981002
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 560.57
[form] => C29H31F3N2O6
[cas] => 1152311-90-4
[pslug] => 1152311-90-4-r-1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-n-1-2-2-dimethyl-1-3-dioxolan-4-yl-methyl-6-fluoro-2-1-hydroxy-2-methylpropan-2-yl-1h-indol-5-yl-cyclopropane-1-carboxamide-pa470981002
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(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
Catalogue No.:PA 47 0981002
Molecular Formula : C29H31F3N2O6
Molecular Weight : 560.57
stdClass Object
(
[pname] => Tezacaftor Metabolite
[catalogue_number] => PA 47 0981003
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 518.49
[form] => C26H25F3N2O6
[cas] => 1432656-97-7
[pslug] => 1432656-97-7-tezacaftor-metabolite-pa470981003
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Catalogue No.:PA 47 0981003
Molecular Formula : C26H25F3N2O6
Molecular Weight : 518.49