Tezacaftor-impurities | Pharmaffiliates

Tezacaftor

Tezacaftor is used to treat cystic fibrosis in certain people. It is a drug that is sold as a fixed-dose combination with ivacaftor as Symdeko.Reference standards of Tezacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Tezacaftor - API Standards 
    [catalogue_number] => PA 47 98000
    [category_ids] => ,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 520.51
    [form] => C26H27F3N2O6
    [cas] => 1152311-62-0
    [pslug] => 1152311-62-0-tezacaftor-api-pa4798000
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PA 47 98000

Tezacaftor - API Standards


  • Catalogue No.:PA 47 98000

  • CAS :

    1152311-62-0

  • Molecular Formula : C26H27F3N2O6

  • Molecular Weight : 520.51

stdClass Object
(
    [pname] => 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(8-fluoro-2-hydroxy-4-(hydroxymethyl)-1,1-dimethyl-1,2,4,5-tetrahydro-[1,4]oxazepino[4,5-a]indol-9-yl)cyclopropane-1-carboxamide
    [catalogue_number] => PA 47 0981000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 518.49
    [form] => C26H25F3N2O6
    [cas] => 1432657-04-9
    [pslug] => 1432657-04-9-1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-n-8-fluoro-2-hydroxy-4-hydroxymethyl-1-1-dimethyl-1-2-4-5-tetrahydro-1-4-oxazepino-4-5-a-indol-9-yl-cyclopropane-1-carboxamide-pa470981000
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PA 47 0981000

1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(8-fluoro-2-hydroxy-4-(hydroxymethyl)-1,1-dimethyl-1,2,4,5-tetrahydro-[1,4]oxazepino[4,5-a]indol-9-yl)cyclopropane-1-carboxamide


  • Catalogue No.:PA 47 0981000

  • CAS :

    1432657-04-9

  • Molecular Formula : C26H25F3N2O6

  • Molecular Weight : 518.49

stdClass Object
(
    [pname] => (R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
    [catalogue_number] => PA 47 0981001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 476.59
    [form] => C29H33FN2O3
    [cas] => 1294504-67-8
    [pslug] => 1294504-67-8-r-1-5-amino-2-1-benzyloxy-2-methylpropan-2-yl-6-fluoro-1h-indol-1-yl-3-benzyloxy-propan-2-ol-pa470981001
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PA 47 0981001

(R)-1-(5-Amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol


  • Catalogue No.:PA 47 0981001

  • CAS :

    1294504-67-8

  • Molecular Formula : C29H33FN2O3

  • Molecular Weight : 476.59

stdClass Object
(
    [pname] => (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
    [catalogue_number] => PA 47 0981002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 560.57
    [form] => C29H31F3N2O6
    [cas] => 1152311-90-4
    [pslug] => 1152311-90-4-r-1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-n-1-2-2-dimethyl-1-3-dioxolan-4-yl-methyl-6-fluoro-2-1-hydroxy-2-methylpropan-2-yl-1h-indol-5-yl-cyclopropane-1-carboxamide-pa470981002
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PA 47 0981002

(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide


  • Catalogue No.:PA 47 0981002

  • CAS :

    1152311-90-4

  • Molecular Formula : C29H31F3N2O6

  • Molecular Weight : 560.57

stdClass Object
(
    [pname] => Tezacaftor Metabolite
    [catalogue_number] => PA 47 0981003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 518.49
    [form] => C26H25F3N2O6
    [cas] => 1432656-97-7
    [pslug] => 1432656-97-7-tezacaftor-metabolite-pa470981003
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PA 47 0981003

Tezacaftor Metabolite


  • Catalogue No.:PA 47 0981003

  • CAS :

    1432656-97-7

  • Molecular Formula : C26H25F3N2O6

  • Molecular Weight : 518.49