Tovorafenib
Pharmaceutical standards
- Tovorafenib, known as Ojemda, is an oral, selective type II RAF kinase inhibitor for treating children aged 6 months and older with relapsed or refractory pediatric low-grade glioma (pLGG) having a BRAF fusion, rearrangement, or V600E mutation. Reference standards of Tovorafenib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[catalogue_number] => PA 20 4120000
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[weight] => 506.29
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Catalogue No.:PA 20 4120000
Molecular Formula : C17H12Cl2F3N7O2S
Molecular Weight : 506.29
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[pname] => (R)-2-(1-Aminoethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide
[catalogue_number] => PA 20 4121000
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[chemical_name] =>
[weight] => 350.74
[form] => C12H10ClF3N4OS
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(R)-2-(1-Aminoethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide
Catalogue No.:PA 20 4121000
Molecular Formula : C12H10ClF3N4OS
Molecular Weight : 350.74
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6-Amino-5-chloropyrimidine-4-carboxylic Acid
Catalogue No.:PA 20 4121001
Molecular Formula : C5H4ClN3O2
Molecular Weight : 173.56
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Catalogue No.:PA 20 4121002
Molecular Formula : C17H12Cl2F3N7O2S
Molecular Weight : 506.29
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4-(Trifluoromethyl)pyridine-2,6-diamine
Catalogue No.:PA 20 4121003
Molecular Formula : C6H6F3N3
Molecular Weight : 177.13
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3,5-Dichloro-4-(trifluoromethyl)pyridine-2,6-diamine
Catalogue No.:PA 20 4121004
Molecular Formula : C6H4Cl2F3N3
Molecular Weight : 246.01
stdClass Object
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[weight] => 211.57
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3-Chloro-4-(trifluoromethyl)pyridine-2,6-diamine
Catalogue No.:PA 20 4121005
Molecular Formula : C6H5ClF3N3
Molecular Weight : 211.57
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6-Chloro-4-(trifluoromethyl)pyridin-2-amine
Catalogue No.:PA 20 4121006
Molecular Formula : C6H4ClF3N2
Molecular Weight : 196.56
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5-Chloro-4-(trifluoromethyl)pyridin-3-amine
Catalogue No.:PA 20 4121007
Molecular Formula : C6H4ClF3N2
Molecular Weight : 196.56
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5-Chloro-6-(trifluoromethyl)pyridin-2-amine
Catalogue No.:PA 20 4121008
Molecular Formula : C6H4ClF3N2
Molecular Weight : 196.56
stdClass Object
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[weight] => 181.54
[form] => C6H3ClF3N
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3-Chloro-4-(trifluoromethyl)pyridine
Catalogue No.:PA 20 4121009
Molecular Formula : C6H3ClF3N
Molecular Weight : 181.54
stdClass Object
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[catalogue_number] => PA 20 4121010
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5-Chloropyrimidine-4-carboxylic Acid
Catalogue No.:PA 20 4121010
Molecular Formula : C5H3ClN2O2
Molecular Weight : 158.54
stdClass Object
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[catalogue_number] => PA 20 4121011
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[weight] => 208
[form] => C5H3Cl2N3O2
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5-Amino-2,6-dichloropyrimidine-4-carboxylic Acid
stdClass Object
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[catalogue_number] => PA 20 4121012
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[weight] => 173.56
[form] => C5H4ClN3O2
[cas] => 1446111-08-5
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4-Amino-6-chloropyrimidine-5-carboxylic Acid
Catalogue No.:PA 20 4121012
Molecular Formula : C5H4ClN3O2
Molecular Weight : 173.56
