Trametinib may be used alone or in combination with another medication to treat a type of skin cancer. It is a MEK inhibitor drug with anti-cancer activity.Reference standards of Trametinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Trametinib - API Standards [catalogue_number] => PA 47 14000 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 615.39 [form] => C26H23FIN5O4 [cas] => 871700-17-3 [pslug] => 871700-17-3-trametinib-api-pa4714000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 14000
CAS :
Molecular Formula : C26H23FIN5O4
Molecular Weight : 615.39
stdClass Object ( [pname] => N-(3-(5-((4-Bromo-2-fluorophenyl)amino)-3-cyclopropyl-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide [catalogue_number] => PA 47 14510 [category_ids] => ,80,78,70,82,79,89, [chemical_name] => [weight] => 568.39 [form] => C26H23BrFN5O4 [cas] => NA [pslug] => n-3-5-4-bromo-2-fluorophenyl-amino-3-cyclopropyl-6-8-dimethyl-2-4-7-trioxo-3-4-6-7-tetrahydropyrido-4-3-d-pyrimidin-1-2h-yl-phenyl-acetamide-pa4714510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 14510
Molecular Formula : C26H23BrFN5O4
Molecular Weight : 568.39
stdClass Object ( [pname] => 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione [catalogue_number] => PA 47 14520 [category_ids] => ,78,70,82,89,79,80, [chemical_name] => [weight] => 401.17 [form] => C14H13FIN3O2 [cas] => 871700-22-0 [pslug] => 871700-22-0-3-cyclopropyl-1-2-fluoro-4-iodophenyl-6-methylamino-pyrimidine-2-4-1h-3h-dione-pa4714520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 14520
Molecular Formula : C14H13FIN3O2
Molecular Weight : 401.17
stdClass Object ( [pname] => Trametinib-d4 [catalogue_number] => PA STI 084082 [category_ids] => ,79,80,71,78,70,82,98, [chemical_name] => [weight] => 619.42 [form] => C26H19D4FIN5O4 [cas] => NA [pslug] => trametinib-d4-pasti084082 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 084082
Molecular Formula : C26H19D4FIN5O4
Molecular Weight : 619.42
stdClass Object ( [pname] => Trametinib Dimethyl Sulfoxide [catalogue_number] => PA 47 0141000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 693.53 [form] => C28H29FIN5O5S [cas] => 1187431-43-1 [pslug] => 1187431-43-1-trametinib-dimethyl-sulfoxide-pa470141000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141000
Molecular Formula : C28H29FIN5O5S
Molecular Weight : 693.53
stdClass Object ( [pname] => 1-(3-Aminophenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione [catalogue_number] => PA 47 0141001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 573.37 [form] => C24H21FIN5O3 [cas] => 871701-87-0 [pslug] => 871701-87-0-1-3-aminophenyl-3-cyclopropyl-5-2-fluoro-4-iodophenyl-amino-6-8-dimethylpyrido-4-3-d-pyrimidine-2-4-7-1h-3h-6h-trione-pa470141001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141001
Molecular Formula : C24H21FIN5O3
Molecular Weight : 573.37
stdClass Object ( [pname] => 1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione [catalogue_number] => PA 47 0141002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 589.37 [form] => C24H21FIN5O4 [cas] => 1620017-29-9 [pslug] => 1620017-29-9-1-3-amino-4-hydroxyphenyl-3-cyclopropyl-5-2-fluoro-4-iodophenyl-amino-6-8-dimethylpyrido-4-3-d-pyrimidine-2-4-7-1h-3h-6h-trione-pa470141002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141002
Molecular Formula : C24H21FIN5O4
Molecular Weight : 589.37
stdClass Object ( [pname] => 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione [catalogue_number] => PA 47 0141005 [category_ids] => ,80,78,70,82,76, [chemical_name] => [weight] => 483.24 [form] => C18H15FIN3O4 [cas] => 871700-24-2 [pslug] => 871700-24-2-3-cyclopropyl-1-2-fluoro-4-iodophenyl-5-hydroxy-6-8-dimethylpyrido-2-3-d-pyrimidine-2-4-7-1h-3h-8h-trione-pa470141005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141005
Molecular Formula : C18H15FIN3O4
Molecular Weight : 483.24
stdClass Object ( [pname] => N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)amino)phenyl)acetamide [catalogue_number] => PA 47 0141004 [category_ids] => ,80,78,70,82,76, [chemical_name] => [weight] => 615.4 [form] => C26H23FIN5O4 [cas] => 871700-25-3 [pslug] => 871700-25-3-n-3-3-cyclopropyl-1-2-fluoro-4-iodophenyl-6-8-dimethyl-2-4-7-trioxo-1-2-3-4-7-8-hexahydropyrido-2-3-d-pyrimidin-5-yl-amino-phenyl-acetamide-pa470141004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141004
Molecular Weight : 615.4
stdClass Object ( [pname] => Desiodo Trametinib [catalogue_number] => PA 47 0141003 [category_ids] => ,80,78,70,82,76, [chemical_name] => [weight] => 489.51 [form] => C26H24FN5O4 [cas] => 871700-65-1 [pslug] => 871700-65-1-desiodo-trametinib-pa470141003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141003
Molecular Formula : C26H24FN5O4
Molecular Weight : 489.51
stdClass Object ( [pname] => N-Cyclopropyl-2-((2-fluoro-4-iodophenyl)amino)-4-hydroxy-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide [catalogue_number] => PA 47 0141006 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 457.24 [form] => C17H17FIN3O3 [cas] => NA [pslug] => n-cyclopropyl-2-2-fluoro-4-iodophenyl-amino-4-hydroxy-1-5-dimethyl-6-oxo-1-6-dihydropyridine-3-carboxamide-pa470141006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141006
Molecular Formula : C17H17FIN3O3
Molecular Weight : 457.24
stdClass Object ( [pname] => N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide [catalogue_number] => PA 47 0141007 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 631.4 [form] => C26H23FIN5O5 [cas] => 1383430-03-2 [pslug] => 1383430-03-2-n-3-3-cyclopropyl-5-2-fluoro-4-iodophenyl-imino-8-hydroxy-6-8-dimethyl-2-4-7-trioxo-3-4-5-6-7-8-hexahydropyrido-4-3-d-pyrimidin-1-2h-yl-phenyl-acetamide-pa470141007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141007
Molecular Formula : C26H23FIN5O5
Molecular Weight : 631.4
stdClass Object ( [pname] => N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)imino)-8-hydroperoxy-6,8-dimethyl-2,4,7-trioxo-3,4,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide [catalogue_number] => PA 47 0141008 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 647.4 [form] => C26H23FIN5O6 [cas] => 1383430-04-3 [pslug] => 1383430-04-3-n-3-3-cyclopropyl-5-2-fluoro-4-iodophenyl-imino-8-hydroperoxy-6-8-dimethyl-2-4-7-trioxo-3-4-5-6-7-8-hexahydropyrido-4-3-d-pyrimidin-1-2h-yl-phenyl-acetamide-pa470141008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141008
Molecular Formula : C26H23FIN5O6
Molecular Weight : 647.4
stdClass Object ( [pname] => 3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-1-(3-nitrophenyl)pyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione [catalogue_number] => PA 47 0141009 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 603.35 [form] => C24H19FIN5O5 [cas] => 1279693-89-8 [pslug] => 1279693-89-8-3-cyclopropyl-5-2-fluoro-4-iodophenyl-amino-6-8-dimethyl-1-3-nitrophenyl-pyrido-4-3-d-pyrimidine-2-4-7-1h-3h-6h-trione-pa470141009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141009
Molecular Formula : C24H19FIN5O5
Molecular Weight : 603.35
stdClass Object ( [pname] => N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)(nitroso)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide [catalogue_number] => PA 47 0141010 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 644.4 [form] => C26H22FIN6O5 [cas] => NA [pslug] => n-3-3-cyclopropyl-5-2-fluoro-4-iodophenyl-nitroso-amino-6-8-dimethyl-2-4-7-trioxo-3-4-6-7-tetrahydropyrido-4-3-d-pyrimidin-1-2h-yl-phenyl-acetamide-pa470141010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141010
Molecular Formula : C26H22FIN6O5
Molecular Weight : 644.4
stdClass Object ( [pname] => N-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-methylnitrous amide [catalogue_number] => PA 47 0141011 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 430.18 [form] => C14H12FIN4O3 [cas] => NA [pslug] => n-1-cyclopropyl-3-2-fluoro-4-iodophenyl-2-6-dioxo-1-2-3-6-tetrahydropyrimidin-4-yl-n-methylnitrous-amide-pa470141011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141011
Molecular Formula : C14H12FIN4O3
Molecular Weight : 430.18
stdClass Object ( [pname] => N-(3-((3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl)(nitroso)amino)phenyl)acetamide [catalogue_number] => PA 47 0141012 [category_ids] => ,70,78,82,162, [chemical_name] => [weight] => 644.4 [form] => C26H22FIN6O5 [cas] => NA [pslug] => n-3-3-cyclopropyl-1-2-fluoro-4-iodophenyl-6-8-dimethyl-2-4-7-trioxo-1-2-3-4-7-8-hexahydropyrido-2-3-d-pyrimidin-5-yl-nitroso-amino-phenyl-acetamide-pa470141012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 47 0141012
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