Upadacitinib, sold under the brand name Rinvoq, is a Janus kinase (JAK) inhibitor medication for the treatment of moderately to severely active rheumatoid arthritis in adults. where, its methotrexate a drug used to treat active arthritis. Reference standards of Upadacitinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Catalogue No.:PA 21 0180000
CAS :
Molecular Formula : C17H19F3N6O
Molecular Weight : 380.38
stdClass Object ( [pname] => (3S,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 380.38 [form] => C17H19F3N6O [cas] => NA [pslug] => 3s-4s-3-ethyl-4-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181000
stdClass Object ( [pname] => (3R,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 380.38 [form] => C17H19F3N6O [cas] => NA [pslug] => 3r-4r-3-ethyl-4-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181002
stdClass Object ( [pname] => (3S,4R)-3-Ethyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181003 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 534.56 [form] => C24H25F3N6O3S [cas] => 2411540-30-0 [pslug] => 2411540-30-0-3s-4r-3-ethyl-4-3-tosyl-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181003
Molecular Formula : C24H25F3N6O3S
Molecular Weight : 534.56
stdClass Object ( [pname] => Benzyl (3S,4S)-3-acetyl-4-ethylpyrrolidine-1-carboxylate [catalogue_number] => PA 21 0181004 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 275.35 [form] => C16H21NO3 [cas] => 2868258-95-9 [pslug] => 2868258-95-9-benzyl-3s-4s-3-acetyl-4-ethylpyrrolidine-1-carboxylate-pa210181004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181004
Molecular Formula : C16H21NO3
Molecular Weight : 275.35
stdClass Object ( [pname] => Benzyl (3R,4S)-3-(2,2-dibromoacetyl)-4-ethylpyrrolidine-1-carboxylate [catalogue_number] => PA 21 0181005 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 433.14 [form] => C16H19Br2NO3 [cas] => NA [pslug] => benzyl-3r-4s-3-2-2-dibromoacetyl-4-ethylpyrrolidine-1-carboxylate-pa210181005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181005
Molecular Formula : C16H19Br2NO3
Molecular Weight : 433.14
stdClass Object ( [pname] => 8-((3R,4S)-4-Ethylpyrrolidin-3-yl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine [catalogue_number] => PA 21 0181006 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 255.33 [form] => C14H17N5 [cas] => 1708997-43-6 [pslug] => 1708997-43-6-8-3r-4s-4-ethylpyrrolidin-3-yl-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazine-pa210181006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181006
Molecular Formula : C14H17N5
Molecular Weight : 255.33
stdClass Object ( [pname] => (3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181007 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 380.38 [form] => C17H19F3N6O [cas] => 1310726-59-0 [pslug] => 1310726-59-0-3r-4s-3-ethyl-4-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181007
stdClass Object ( [pname] => rel-(3R,4S)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181008 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 380.38 [form] => C17H19F3N6O [cas] => 1831899-72-9 [pslug] => 1831899-72-9-rel-3r-4s-3-ethyl-4-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181008
stdClass Object ( [pname] => (3S,4R)-3-Ethyl-4-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181009 [category_ids] => ,70,75,76,78,82,162, [chemical_name] => [weight] => 409.37 [form] => C17H18F3N7O2 [cas] => NA [pslug] => 3s-4r-3-ethyl-4-3-nitroso-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181009
Molecular Formula : C17H18F3N7O2
Molecular Weight : 409.37
stdClass Object ( [pname] => (S)-N-Ethyl-3-(3-nitroso-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181010 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 409.37 [form] => C17H18F3N7O2 [cas] => NA [pslug] => s-n-ethyl-3-3-nitroso-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181010
stdClass Object ( [pname] => Benzyl (3R,4S)-3-(2-chloroacetyl)-4-ethylpyrrolidine-1-carboxylate [catalogue_number] => PA 21 0181011 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 309.79 [form] => C16H20ClNO3 [cas] => 2460133-49-5 [pslug] => 2460133-49-5-benzyl-3r-4s-3-2-chloroacetyl-4-ethylpyrrolidine-1-carboxylate-pa210181011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181011
Molecular Formula : C16H20ClNO3
Molecular Weight : 309.79
stdClass Object ( [pname] => (3S,4R)-3-Ethyl-4-(3-(hydroxymethyl)-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide [catalogue_number] => PA 21 0181012 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 410.4 [form] => C18H21F3N6O2 [cas] => NA [pslug] => 3s-4r-3-ethyl-4-3-hydroxymethyl-3h-imidazo-1-2-a-pyrrolo-2-3-e-pyrazin-8-yl-n-2-2-2-trifluoroethyl-pyrrolidine-1-carboxamide-pa210181012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 21 0181012
Molecular Formula : C18H21F3N6O2
Molecular Weight : 410.4
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