Vadadustat
Pharmaceutical standards
- Vadadustat, sold under the brand name Vafseo. It is an oral hypoxia-inducible factor prolyl-hydroxylase inhibitor used to treat symptomatic anemia associated with chronic kidney disease. Reference standards of Vadadustat API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Vadadustat
[catalogue_number] => PA 22 1150000
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[chemical_name] =>
[weight] => 306.7
[form] => C14H11ClN2O4
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[pname] => 3,5-Dichloropicolinonitrile
[catalogue_number] => PA 22 1151000
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[chemical_name] =>
[weight] => 173
[form] => C6H2Cl2N2
[cas] => 85331-33-5
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3,5-Dichloropicolinonitrile
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(
[pname] => 2-Bromo-3,5-dichloropyridine
[catalogue_number] => PA 22 1151001
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[chemical_name] =>
[weight] => 226.88
[form] => C5H2BrCl2N
[cas] => 14482-51-0
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2-Bromo-3,5-dichloropyridine
Catalogue No.:PA 22 1151001
Molecular Formula : C5H2BrCl2N
Molecular Weight : 226.88
stdClass Object
(
[pname] => Dimethyl (3-chlorophenyl)boronate
[catalogue_number] => PA 22 1151002
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 184.43
[form] => C8H10BClO2
[cas] => 1887760-70-4
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Dimethyl (3-chlorophenyl)boronate
Catalogue No.:PA 22 1151002
Molecular Formula : C8H10BClO2
Molecular Weight : 184.43
stdClass Object
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[pname] => 3,3'-Dibromo-1,1'-biphenyl
[catalogue_number] => PA 22 1151003
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 312
[form] => C12H8Br2
[cas] => 16400-51-4
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3,3'-Dibromo-1,1'-biphenyl
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(
[pname] => Methyl glycylglycinate
[catalogue_number] => PA 22 1151004
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 146.15
[form] => C5H10N2O3
[cas] => 5619-16-9
[pslug] => 5619-16-9-methyl-glycylglycinate-pa221151004
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Catalogue No.:PA 22 1151004
Molecular Formula : C5H10N2O3
Molecular Weight : 146.15
stdClass Object
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[pname] => 3-Chloropicolinonitrile
[catalogue_number] => PA 22 1151005
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 138.55
[form] => C6H3ClN2
[cas] => 38180-46-0
[pslug] => 38180-46-0-3-chloropicolinonitrile-pa221151005
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Catalogue No.:PA 22 1151005
Molecular Formula : C6H3ClN2
Molecular Weight : 138.55
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[pname] => 5-Chloropicolinonitrile
[catalogue_number] => PA 22 1151006
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[weight] => 138.55
[form] => C6H3ClN2
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Catalogue No.:PA 22 1151006
Molecular Formula : C6H3ClN2
Molecular Weight : 138.55
stdClass Object
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[pname] => 3-(3-Chlorophenyl)picolinonitrile
[catalogue_number] => PA 22 1151007
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[chemical_name] =>
[weight] => 214.65
[form] => C12H7ClN2
[cas] => 1779963-35-7
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3-(3-Chlorophenyl)picolinonitrile
Catalogue No.:PA 22 1151007
Molecular Formula : C12H7ClN2
Molecular Weight : 214.65
stdClass Object
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[pname] => 5-(3-Chlorophenyl)-3-methoxypicolinonitrile
[catalogue_number] => PA 22 1151008
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[weight] => 244.68
[form] => C13H9ClN2O
[cas] => 1415226-39-9
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5-(3-Chlorophenyl)-3-methoxypicolinonitrile
Catalogue No.:PA 22 1151008
Molecular Formula : C13H9ClN2O
Molecular Weight : 244.68
stdClass Object
(
[pname] => Methyl 5-(3-chlorophenyl)-3-hydroxypicolinate
[catalogue_number] => PA 22 1151009
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 244.68
[form] => C13H10ClNO3
[cas] => 2437189-72-3
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Methyl 5-(3-chlorophenyl)-3-hydroxypicolinate
Catalogue No.:PA 22 1151009
Molecular Formula : C13H10ClNO3
Molecular Weight : 244.68
stdClass Object
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[pname] => 5-(3-Chlorophenyl)-3-hydroxypicolinic Acid
[catalogue_number] => PA 22 1151010
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 249.65
[form] => C12H8ClNO3
[cas] => 1415226-40-2
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5-(3-Chlorophenyl)-3-hydroxypicolinic Acid
Catalogue No.:PA 22 1151010
Molecular Formula : C12H8ClNO3
Molecular Weight : 249.65
stdClass Object
(
[pname] => Vadadustat Methoxy Impurity
[catalogue_number] => PA 22 1151011
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 339.17
[form] => C15H12Cl2N2O3
[cas] => 1987854-29-4
[pslug] => 1987854-29-4-vadadustat-methoxy-impurity-pa221151011
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Vadadustat Methoxy Impurity
Catalogue No.:PA 22 1151011
Molecular Formula : C15H12Cl2N2O3
Molecular Weight : 339.17
stdClass Object
(
[pname] => Vadadustat Methyl Acetate Impurity
[catalogue_number] => PA 22 1151012
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 320.73
[form] => C15H13ClN2O4
[cas] => 1000024-87-2
[pslug] => 1000024-87-2-vadadustat-methyl-acetate-impurity-pa221151012
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Vadadustat Methyl Acetate Impurity
Catalogue No.:PA 22 1151012
Molecular Formula : C15H13ClN2O4
Molecular Weight : 320.73
stdClass Object
(
[pname] => Bis((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)amine
[catalogue_number] => PA 22 1151013
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 320.73
[form] => C15H13ClN2O4
[cas] => 1007381-90-9
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Bis((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)amine
Catalogue No.:PA 22 1151013
Molecular Formula : C15H13ClN2O4
Molecular Weight : 320.73
