darunavir

Sulphur and selenium compounds - A second-generation protease inhibitor, it is used for the treatment of HIV infections. It is administered along with ritonavir or cobicistat, to decrease metabolism and increase concentration.. Reference standards of Darunavir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino] propyl]carbamic Acid tert-Butyl Ester
    [catalogue_number] => PA 04 06510
    [category_ids] => ,69,70,88,
    [chemical_name] => 
    [weight] => 491.64
    [form] => C25H37N3O5S
    [cas] => 183004-94-6
    [pslug] => 183004-94-6-1s-2r-1-benzyl-2-hydroxy-3-isobutyl-4-aminophenyl-sulfonyl-amino-propyl-carbamic-acid-tert-butyl-ester-pa0406510
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PA 04 06510
PA 04 06510

[(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino] propyl]carbamic Acid tert-Butyl Ester


  • Catalogue No.:PA 04 06510

  • CAS :

    183004-94-6

  • Molecular Formula : C25H37N3O5S

  • Molecular Weight : 491.64

stdClass Object
(
    [pname] => Darunavir Diamino Impurity
    [catalogue_number] => PA 04 06570
    [category_ids] => ,88,82,80,79,78,76,75,70,
    [chemical_name] => 
    [weight] => 391.53
    [form] => C20H29N3O3S
    [cas] => 169280-56-2
    [pslug] => 169280-56-2-darunavir-diamino-impurity-pa0406570
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PA 04 06570
PA 04 06570

Darunavir Diamino Impurity


  • Catalogue No.:PA 04 06570

  • CAS :

    169280-56-2

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => Darunavir Urea Impurity
    [catalogue_number] => PA 04 06580
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 2514705-71-4
    [pslug] => 2514705-71-4-darunavir-urea-impurity-pa0406580
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PA 04 06580
PA 04 06580

Darunavir Urea Impurity


  • Catalogue No.:PA 04 06580

  • CAS :

    2514705-71-4

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
(
    [pname] => Darunavir Amine Dimer Impurity
    [catalogue_number] => PA 04 06590
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 965.19
    [form] => C48H64N6O11S2
    [cas] => NA
    [pslug] => darunavir-amine-dimer-impurity-pa0406590
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PA 04 06590
PA 04 06590

Darunavir Amine Dimer Impurity


  • Catalogue No.:PA 04 06590

  • CAS :

    NA

  • Molecular Formula : C48H64N6O11S2

  • Molecular Weight : 965.19

stdClass Object
(
    [pname] => Darunavir Furan Dimer Impurity
    [catalogue_number] => PA 04 06600
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 703.8
    [form] => C34H45N3O11S
    [cas] => NA
    [pslug] => darunavir-furan-dimer-impurity-pa0406600
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PA 04 06600
PA 04 06600

Darunavir Furan Dimer Impurity


  • Catalogue No.:PA 04 06600

  • CAS :

    NA

  • Molecular Formula : C34H45N3O11S

  • Molecular Weight : 703.8

stdClass Object
(
    [pname] => Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate
    [catalogue_number] => PA 04 06610
    [category_ids] => ,80,79,78,82,70,88,71,
    [chemical_name] => 
    [weight] => 867.09
    [form] => C43H58N6O9S2
    [cas] => NA
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PA 04 06610
PA 04 06610

Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate


  • Catalogue No.:PA 04 06610

  • CAS :

    NA

  • Molecular Formula : C43H58N6O9S2

  • Molecular Weight : 867.09

stdClass Object
(
    [pname] => [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester
    [catalogue_number] => PA 04 06620
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 525.66
    [form] => C28H35N3O5S
    [cas] => 159005-61-5
    [pslug] => 159005-61-5-1s-2r-3-4-aminophenyl-sulfonyl-2-methylpropyl-amino-2-hydroxy-1-phenylmethyl-propyl-carbamic-acid-phenylmethyl-ester-pa0406620
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PA 04 06620
PA 04 06620

[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester


  • Catalogue No.:PA 04 06620

  • CAS :

    159005-61-5

  • Molecular Formula : C28H35N3O5S

  • Molecular Weight : 525.66

stdClass Object
(
    [pname] => ((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester
    [catalogue_number] => PA 04 06630
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 681.8
    [form] => C35H43N3O9S
    [cas] => NA
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PA 04 06630
PA 04 06630

((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester


  • Catalogue No.:PA 04 06630

  • CAS :

    NA

  • Molecular Formula : C35H43N3O9S

  • Molecular Weight : 681.8

stdClass Object
(
    [pname] => (+)-Darunavir
    [catalogue_number] => PA 04 06640
    [category_ids] => ,80,79,78,82,70,88,
    [chemical_name] => 
    [weight] => 547.66
    [form] => C27H37N3O7S
    [cas] => 1399859-60-9
    [pslug] => 1399859-60-9-darunavir-pa0406640
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PA 04 06640
PA 04 06640

(+)-Darunavir


  • Catalogue No.:PA 04 06640

  • CAS :

    1399859-60-9

  • Molecular Formula : C27H37N3O7S

  • Molecular Weight : 547.66

stdClass Object
(
    [pname] => Darunavir Carbamic Acid Impurity
    [catalogue_number] => PA 04 06660
    [category_ids] => ,80,71,78,70,82,79,88,
    [chemical_name] => 
    [weight] => 435.54
    [form] => C21H29N3O5S
    [cas] => 1526916-56-2
    [pslug] => 1526916-56-2-darunavir-carbamic-acid-impurity-pa0406660
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PA 04 06660
PA 04 06660

Darunavir Carbamic Acid Impurity


  • Catalogue No.:PA 04 06660

  • CAS :

    1526916-56-2

  • Molecular Formula : C21H29N3O5S

  • Molecular Weight : 435.54

stdClass Object
(
    [pname] => 4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide
    [catalogue_number] => PA 04 06670
    [category_ids] => ,88,82,80,79,71,70,78,
    [chemical_name] => 
    [weight] => 417.52
    [form] => C21H27N3O4S
    [cas] => 1418639-27-6
    [pslug] => 1418639-27-6-4-amino-n-2-methylpropyl-n-4s-5r-2-oxo-4-phenylmethyl-5-oxazolidinyl-methyl-benzenesulfonamide-pa0406670
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PA 04 06670
PA 04 06670

4-Amino-N-(2-methylpropyl)-N-[[(4S,5R)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-benzenesulfonamide


  • Catalogue No.:PA 04 06670

  • CAS :

    1418639-27-6

  • Molecular Formula : C21H27N3O4S

  • Molecular Weight : 417.52

stdClass Object
(
    [pname] => [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid Methyl Ester 
    [catalogue_number] => PA 04 06680
    [category_ids] => ,75,88,70,82,
    [chemical_name] => 
    [weight] => 449.56
    [form] => C22H31N3O5S
    [cas] => 1526916-57-3
    [pslug] => 1526916-57-3-1s-2r-3-4-aminophenyl-sulfonyl-2-methylpropyl-amino-2-hydroxy-1-phenyl-methyl-propyl-carabamic-acid-methyl-ester-pa0406680
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PA 04 06680
PA 04 06680

[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid Methyl Ester


  • Catalogue No.:PA 04 06680

  • CAS :

    1526916-57-3

  • Molecular Formula : C22H31N3O5S

  • Molecular Weight : 449.56

stdClass Object
(
    [pname] => (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-1-isobutylureido)phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
    [catalogue_number] => PA 04 06690
    [category_ids] => ,75,88,70,82,
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    [weight] => 965.19
    [form] => C48H64N6O11S2
    [cas] => NA
    [pslug] => 3r-3as-6ar-hexahydrofuro-2-3-b-furan-3-yl-2s-3r-4-4-3-2s-3r-4-4-amino-n-isobutylphenylsulfonamido-3-hydroxy-1-phenylbutan-2-yl-1-isobutylureido-phenylsulfonamido-3-hydroxy-1-phenylbutan-2-yl-carbamate-pa0406690
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PA 04 06690
PA 04 06690

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-1-isobutylureido)phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate


  • Catalogue No.:PA 04 06690

  • CAS :

    NA

  • Molecular Formula : C48H64N6O11S2

  • Molecular Weight : 965.19

stdClass Object
(
    [pname] => 4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
    [catalogue_number] => PA 04 06730
    [category_ids] => ,79,80,78,70,82,88,75,
    [chemical_name] => 
    [weight] => 391.53
    [form] => C20H29N3O3S
    [cas] => 192800-79-6
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PA 04 06730
PA 04 06730

4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide


  • Catalogue No.:PA 04 06730

  • CAS :

    192800-79-6

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => 4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide
    [catalogue_number] => PA 04 06740
    [category_ids] => ,79,80,78,70,82,88,75,
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    [weight] => 391.53
    [form] => C20H29N3O3S
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PA 04 06740
PA 04 06740

4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide


  • Catalogue No.:PA 04 06740

  • CAS :

    1402142-62-4

  • Molecular Formula : C20H29N3O3S

  • Molecular Weight : 391.53

stdClass Object
(
    [pname] => 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide
    [catalogue_number] => PA STI 005160
    [category_ids] => ,79,80,76,75,78,70,82,88,98,
    [chemical_name] => 
    [weight] => 400.58
    [form] => C20H20D9N3O3S
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PA STI 005160
PA STI 005160

4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide


  • Catalogue No.:PA STI 005160

  • CAS :

    1146967-60-3

  • Molecular Formula : C20H20D9N3O3S

  • Molecular Weight : 400.58

stdClass Object
(
    [pname] => 2,5-Dioxopyrrolidin-1-yl ((3R,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate
    [catalogue_number] => PA 04 06820
    [category_ids] => ,69,70,88,
    [chemical_name] => 
    [weight] => 271.23
    [form] => C11H13NO7
    [cas] => 799241-86-4
    [pslug] => 799241-86-4-2-5-dioxopyrrolidin-1-yl-3r-3ar-6as-hexahydrofuro-2-3-b-furan-3-yl-carbonate-pa0406820
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PA 04 06820
PA 04 06820

2,5-Dioxopyrrolidin-1-yl ((3R,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate


  • Catalogue No.:PA 04 06820

  • CAS :

    799241-86-4

  • Molecular Formula : C11H13NO7

  • Molecular Weight : 271.23

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