lifitegrast

Sulphur and selenium compounds - lifitegrast is used to treat the signs and symptoms of dry eye disease. It is an FDA approved drug indicated. Lifitegrast reduces inflammation by inhibiting inflammatory cell binding. Reference standards of Lifitegrast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Lifitegrast
    [catalogue_number] => PA 39 04000
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 615.48
    [form] => C29H24Cl2N2O7S
    [cas] => 1025967-78-5
    [pslug] => 1025967-78-5-lifitegrast-api-pa3904000
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PA 39 04000
PA 39 04000

Lifitegrast


  • Catalogue No.:PA 39 04000

  • CAS :

    1025967-78-5

  • Molecular Formula : C29H24Cl2N2O7S

  • Molecular Weight : 615.48

stdClass Object
(
    [pname] => 5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride
    [catalogue_number] => PA 39 0041011
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 282.55
    [form] => C10H10Cl3NO2
    [cas] => 1289646-93-0
    [pslug] => 1289646-93-0-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxylic-acid-hydrochloride-pa390041011
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PA 39 0041011
PA 39 0041011

5,7-Dichloro-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid Hydrochloride


  • Catalogue No.:PA 39 0041011

  • CAS :

    1289646-93-0

  • Molecular Formula : C10H10Cl3NO2

  • Molecular Weight : 282.55

stdClass Object
(
    [pname] => (S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 0041016
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 471.35
    [form] => C20H20Cl2N2O5S
    [cas] => 851785-70-1
    [pslug] => 851785-70-1-s-2-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoic-acid-pa390041016
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PA 39 0041016
PA 39 0041016

(S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 0041016

  • CAS :

    851785-70-1

  • Molecular Formula : C20H20Cl2N2O5S

  • Molecular Weight : 471.35

stdClass Object
(
    [pname] => 5,7-Dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid
    [catalogue_number] => PA 39 0041017
    [category_ids] => ,79,80,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 275.09
    [form] => C10H8Cl2N2O3
    [cas] => NA
    [pslug] => 5-7-dichloro-2-nitroso-1-2-3-4-tetrahydroisoquinoline-6-carboxylic-acid-pa390041017
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PA 39 0041017
PA 39 0041017

5,7-Dichloro-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6-carboxylic Acid


  • Catalogue No.:PA 39 0041017

  • CAS :

    NA

  • Molecular Formula : C10H8Cl2N2O3

  • Molecular Weight : 275.09

stdClass Object
(
    [pname] => tert-Butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
    [catalogue_number] => PA 39 0041018
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 671.59
    [form] => C33H32Cl2N2O7S
    [cas] => 2414639-05-5
    [pslug] => 2414639-05-5-tert-butyl-s-2-2-benzofuran-6-carbonyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoate-pa390041018
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PA 39 0041018
PA 39 0041018

tert-Butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate


  • Catalogue No.:PA 39 0041018

  • CAS :

    2414639-05-5

  • Molecular Formula : C33H32Cl2N2O7S

  • Molecular Weight : 671.59

stdClass Object
(
    [pname] => (2S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 0041019
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 631.48
    [form] => C29H24Cl2N2O8S
    [cas] => NA
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PA 39 0041019
PA 39 0041019

(2S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1-hydroxy-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 0041019

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

stdClass Object
(
    [pname] => (2S)-2-(5,7-Dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 0041020
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    [chemical_name] => 
    [weight] => 649.49
    [form] => C29H26Cl2N2O9S
    [cas] => NA
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PA 39 0041020
PA 39 0041020

(2S)-2-(5,7-Dichloro-2-(2,3-dihydroxy-2,3-dihydrobenzofuran-6-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 0041020

  • CAS :

    NA

  • Molecular Formula : C29H26Cl2N2O9S

  • Molecular Weight : 649.49

stdClass Object
(
    [pname] => (2S)-2-(5,7-Dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 0041021
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 631.48
    [form] => C29H24Cl2N2O8S
    [cas] => NA
    [pslug] => 2s-2-5-7-dichloro-2-1a-6b-dihydrooxireno-2-3-b-benzofuran-4-carbonyl-1-2-3-4-tetrahydroisoquinoline-6-carboxamido-3-3-methylsulfonyl-phenyl-propanoic-acid-pa390041021
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PA 39 0041021
PA 39 0041021

(2S)-2-(5,7-Dichloro-2-(1a,6b-dihydrooxireno[2,3-b]benzofuran-4-carbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 0041021

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

stdClass Object
(
    [pname] => 3,5-Dichloro-N-(2-hydroxyethyl)benzamide
    [catalogue_number] => PA 39 0041025
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 234.08
    [form] => C9H9Cl2NO2
    [cas] => 344307-65-9
    [pslug] => 344307-65-9-3-5-dichloro-n-2-hydroxyethyl-benzamide-pa390041025
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PA 39 0041025
PA 39 0041025

3,5-Dichloro-N-(2-hydroxyethyl)benzamide


  • Catalogue No.:PA 39 0041025

  • CAS :

    344307-65-9

  • Molecular Formula : C9H9Cl2NO2

  • Molecular Weight : 234.08

stdClass Object
(
    [pname] => 2-((3,5-Dichlorobenzyl)amino)ethan-1-ol
    [catalogue_number] => PA 39 0041026
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 220.09
    [form] => C9H11Cl2NO
    [cas] => 1183137-67-8
    [pslug] => 1183137-67-8-2-3-5-dichlorobenzyl-amino-ethan-1-ol-pa390041026
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PA 39 0041026
PA 39 0041026

2-((3,5-Dichlorobenzyl)amino)ethan-1-ol


  • Catalogue No.:PA 39 0041026

  • CAS :

    1183137-67-8

  • Molecular Formula : C9H11Cl2NO

  • Molecular Weight : 220.09

stdClass Object
(
    [pname] => 5,7-Dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline
    [catalogue_number] => PA 39 0041027
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 444.4
    [form] => C28H23Cl2N
    [cas] => 1289646-72-5
    [pslug] => 1289646-72-5-5-7-dichloro-2-trityl-1-2-3-4-tetrahydroisoquinoline-pa390041027
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PA 39 0041027
PA 39 0041027

5,7-Dichloro-2-trityl-1,2,3,4-tetrahydroisoquinoline


  • Catalogue No.:PA 39 0041027

  • CAS :

    1289646-72-5

  • Molecular Formula : C28H23Cl2N

  • Molecular Weight : 444.4

stdClass Object
(
    [pname] => Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate
    [catalogue_number] => PA 39 0041028
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 257.3
    [form] => C11H15NO4S
    [cas] => 1213360-49-6
    [pslug] => 1213360-49-6-methyl-r-2-amino-3-3-methylsulfonyl-phenyl-propanoate-pa390041028
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PA 39 0041028
PA 39 0041028

Methyl (R)-2-amino-3-(3-(methylsulfonyl)phenyl)propanoate


  • Catalogue No.:PA 39 0041028

  • CAS :

    1213360-49-6

  • Molecular Formula : C11H15NO4S

  • Molecular Weight : 257.3

stdClass Object
(
    [pname] => 2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid
    [catalogue_number] => PA 39 0041029
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 243.28
    [form] => C10H13NO4S
    [cas] => 1270324-69-0
    [pslug] => 1270324-69-0-2-amino-3-3-methylsulfonyl-phenyl-propanoic-acid-pa390041029
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PA 39 0041029
PA 39 0041029

2-Amino-3-(3-(methylsulfonyl)phenyl)propanoic Acid


  • Catalogue No.:PA 39 0041029

  • CAS :

    1270324-69-0

  • Molecular Formula : C10H13NO4S

  • Molecular Weight : 243.28

stdClass Object
(
    [pname] => 2-(Benzofuran-6-carbonyl)-6-(((S)-1-carboxy-2-(3-(methylsulfonyl)phenyl)ethyl)carbamoyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline 2-oxide
    [catalogue_number] => PA 39 0041030
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 631.48
    [form] => C29H24Cl2N2O8S
    [cas] => NA
    [pslug] => 2-benzofuran-6-carbonyl-6-s-1-carboxy-2-3-methylsulfonyl-phenyl-ethyl-carbamoyl-5-7-dichloro-1-2-3-4-tetrahydroisoquinoline-2-oxide-pa390041030
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PA 39 0041030
PA 39 0041030

2-(Benzofuran-6-carbonyl)-6-(((S)-1-carboxy-2-(3-(methylsulfonyl)phenyl)ethyl)carbamoyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline 2-oxide


  • Catalogue No.:PA 39 0041030

  • CAS :

    NA

  • Molecular Formula : C29H24Cl2N2O8S

  • Molecular Weight : 631.48

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