Venetoclax-impurities | Pharmaffiliates

venetoclax

Venetoclax is used for adults with chronic lymphocytic leukemia or small lymphocytic lymphoma. It is sold under the trade name Venclexta and Venclyxto.Reference standards of Venetoclax API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
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    [pname] => Venetoclax - API
    [catalogue_number] => PA 22 36000
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 868.44
    [form] => C45H50ClN7O7S
    [cas] => 1257044-40-8
    [pslug] => 1257044-40-8-venetoclax-api-pa2236000
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PA 22 36000

Venetoclax - API


  • Catalogue No.:PA 22 36000

  • CAS :

    1257044-40-8

  • Molecular Formula : C45H50ClN7O7S

  • Molecular Weight : 868.44

stdClass Object
(
    [pname] => 3,3'-Oxy-venetoclax
    [catalogue_number] => PA 22 36510
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 882.42
    [form] => C45H48ClN7O8S
    [cas] => NA
    [pslug] => 3-3-oxy-venetoclax-pa2236510
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PA 22 36510

3,3'-Oxy-venetoclax


  • Catalogue No.:PA 22 36510

  • CAS :

    NA

  • Molecular Formula : C45H48ClN7O8S

  • Molecular Weight : 882.42

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic Acid
    [catalogue_number] => PA 22 0361012
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 571.12
    [form] => C33H35ClN4O3
    [cas] => 1235865-77-6
    [pslug] => 1235865-77-6-2-1h-pyrrolo-2-3-b-pyridin-5-yl-oxy-4-4-4-chloro-5-5-dimethyl-3-4-5-6-tetrahydro-1-1-biphenyl-2-yl-methyl-piperazin-1-yl-benzoic-acid-pa220361012
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PA 22 0361012

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic Acid


  • Catalogue No.:PA 22 0361012

  • CAS :

    1235865-77-6

  • Molecular Formula : C33H35ClN4O3

  • Molecular Weight : 571.12

stdClass Object
(
    [pname] => Deschloro Venetoclax Impurity
    [catalogue_number] => PA 22 0361013
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 834.01
    [form] => C45H51N7O7S
    [cas] => 2573767-91-4
    [pslug] => 2573767-91-4-deschloro-venetoclax-impurity-pa220361013
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PA 22 0361013

Deschloro Venetoclax Impurity


  • Catalogue No.:PA 22 0361013

  • CAS :

    2573767-91-4

  • Molecular Formula : C45H51N7O7S

  • Molecular Weight : 834.01

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluoro-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
    [catalogue_number] => PA 22 0361014
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 569.56
    [form] => C26H24FN5O7S
    [cas] => 2573767-90-3
    [pslug] => 2573767-90-3-2-1h-pyrrolo-2-3-b-pyridin-5-yl-oxy-4-fluoro-n-3-nitro-4-tetrahydro-2h-pyran-4-yl-methyl-amino-phenyl-sulfonyl-benzamide-pa220361014
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PA 22 0361014

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluoro-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide


  • Catalogue No.:PA 22 0361014

  • CAS :

    2573767-90-3

  • Molecular Formula : C26H24FN5O7S

  • Molecular Weight : 569.56

stdClass Object
(
    [pname] => 1,1'-((((5,5,5''',5'''-Tetramethyl-3,3''',4,4''',5,5''',6,6'''-octahydro-[1,1':4',1'':4'',1'''-quaterphenyl]-2,2'''-diyl)bis(methylene))bis(piperazine-4,1-diyl))bis(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4,1-phenylene))bis(N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)formamide)
    [catalogue_number] => PA 22 0361015
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 1665.99
    [form] => C90H100N14O14S2
    [cas] => 2412506-53-5
    [pslug] => 2412506-53-5-1-1-5-5-5-5-tetramethyl-3-3-4-4-5-5-6-6-octahydro-1-1-4-1-4-1-quaterphenyl-2-2-diyl-bis-methylene-bis-piperazine-4-1-diyl-bis-2-1h-pyrrolo-2-3-b-pyridin-5-yl-oxy-4-1-phenylene-bis-n-3-nitro-4-tetrahydro-2h-pyran-4-yl-methyl-amino-phenyl-sulfonyl-formamide-pa220361015
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PA 22 0361015

1,1'-((((5,5,5''',5'''-Tetramethyl-3,3''',4,4''',5,5''',6,6'''-octahydro-[1,1':4',1'':4'',1'''-quaterphenyl]-2,2'''-diyl)bis(methylene))bis(piperazine-4,1-diyl))bis(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4,1-phenylene))bis(N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)formamide)


  • Catalogue No.:PA 22 0361015

  • CAS :

    2412506-53-5

  • Molecular Formula : C90H100N14O14S2

  • Molecular Weight : 1665.99

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    [pname] => 1,1'-((((5,5,5'',5''-Tetramethyl-3,3'',4,4'',5,5'',6,6''-octahydro-[1,1':4',1''-terphenyl]-2,2''-diyl)bis(methylene))bis(piperazine-4,1-diyl))bis(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4,1-phenylene))bis(N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)formamide)
    [catalogue_number] => PA 22 0361016
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 1589.9
    [form] => C84H96N14O14S2
    [cas] => NA
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PA 22 0361016

1,1'-((((5,5,5'',5''-Tetramethyl-3,3'',4,4'',5,5'',6,6''-octahydro-[1,1':4',1''-terphenyl]-2,2''-diyl)bis(methylene))bis(piperazine-4,1-diyl))bis(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4,1-phenylene))bis(N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)formamide)


  • Catalogue No.:PA 22 0361016

  • CAS :

    NA

  • Molecular Formula : C84H96N14O14S2

  • Molecular Weight : 1589.9

stdClass Object
(
    [pname] => 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)-4-nitrosopiperazine
    [catalogue_number] => PA 22 0361017
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 347.89
    [form] => C19H26ClN3O
    [cas] => NA
    [pslug] => 1-4-chloro-5-5-dimethyl-3-4-5-6-tetrahydro-1-1-biphenyl-2-yl-methyl-4-nitrosopiperazine-pa220361017
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PA 22 0361017

1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)-4-nitrosopiperazine


  • Catalogue No.:PA 22 0361017

  • CAS :

    NA

  • Molecular Formula : C19H26ClN3O

  • Molecular Weight : 347.89

stdClass Object
(
    [pname] => 3-Nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide
    [catalogue_number] => PA 22 0361018
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 344.34
    [form] => C12H16N4O6S
    [cas] => NA
    [pslug] => 3-nitro-4-nitroso-tetrahydro-2h-pyran-4-yl-methyl-amino-benzenesulfonamide-pa220361018
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PA 22 0361018

3-Nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide


  • Catalogue No.:PA 22 0361018

  • CAS :

    NA

  • Molecular Formula : C12H16N4O6S

  • Molecular Weight : 344.34

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl) methyl)amino)phenyl)sulfonyl)benzamide
    [catalogue_number] => PA 22 0361019
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 897.45
    [form] => C45H49ClN8O8S
    [cas] => NA
    [pslug] => 2-1h-pyrrolo-2-3-b-pyridin-5-yl-oxy-4-4-4-chloro-5-5-dimethyl-3-4-5-6-tetrahydro-1-1-biphenyl-2-yl-methyl-piperazin-1-yl-n-3-nitro-4-nitroso-tetrahydro-2h-pyran-4-yl-methyl-amino-phenyl-sulfonyl-benzamide-pa220361019
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PA 22 0361019

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl) methyl)amino)phenyl)sulfonyl)benzamide


  • Catalogue No.:PA 22 0361019

  • CAS :

    NA

  • Molecular Formula : C45H49ClN8O8S

  • Molecular Weight : 897.45

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5'-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-fluoro-3-nitrophenyl)sulfonyl)benzamide
    [catalogue_number] => PA 22 0361020
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 773.28
    [form] => C39H38ClFN6O6S
    [cas] => NA
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PA 22 0361020

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5'-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-fluoro-3-nitrophenyl)sulfonyl)benzamide


  • Catalogue No.:PA 22 0361020

  • CAS :

    NA

  • Molecular Formula : C39H38ClFN6O6S

  • Molecular Weight : 773.28

stdClass Object
(
    [pname] => 2-((1-Acetyl-1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
    [catalogue_number] => PA 22 0361021
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 910.48
    [form] => C47H52ClN7O8S
    [cas] => 2573767-92-5
    [pslug] => 2573767-92-5-2-1-acetyl-1h-pyrrolo-2-3-b-pyridin-5-yl-oxy-4-4-4-chloro-5-5-dimethyl-3-4-5-6-tetrahydro-1-1-biphenyl-2-yl-methyl-piperazin-1-yl-n-3-nitro-4-tetrahydro-2h-pyran-4-yl-methyl-amino-phenyl-sulfonyl-benzamide-pa220361021
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PA 22 0361021

2-((1-Acetyl-1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide


  • Catalogue No.:PA 22 0361021

  • CAS :

    2573767-92-5

  • Molecular Formula : C47H52ClN7O8S

  • Molecular Weight : 910.48

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-(4-(N-(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-nitrophenyl)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)benzamide
    [catalogue_number] => PA 22 0361022
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 1421.55
    [form] => C78H83Cl2N11O9S
    [cas] => NA
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PA 22 0361022

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-(4-(N-(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-nitrophenyl)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)benzamide


  • Catalogue No.:PA 22 0361022

  • CAS :

    NA

  • Molecular Formula : C78H83Cl2N11O9S

  • Molecular Weight : 1421.55

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(5-(5-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-2-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenoxy)-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
    [catalogue_number] => PA 22 0361023
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 1418.01
    [form] => C71H73ClN12O14S2
    [cas] => 2573767-94-7
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PA 22 0361023

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(5-(5-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-2-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenoxy)-1H-pyrrolo[2,3-b]pyridin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide


  • Catalogue No.:PA 22 0361023

  • CAS :

    2573767-94-7

  • Molecular Formula : C71H73ClN12O14S2

  • Molecular Weight : 1418.01

stdClass Object
(
    [pname] => 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-6-hydroxy-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
    [catalogue_number] => PA 22 0361024
    [category_ids] => ,71,78,70,82,79,80,88,
    [chemical_name] => 
    [weight] => 884.45
    [form] => C45H50ClN7O8S
    [cas] => 2573767-96-9
    [pslug] => 2573767-96-9-2-1h-pyrrolo-2-3-b-pyridin-5-yl-oxy-4-4-4-chloro-6-hydroxy-5-5-dimethyl-3-4-5-6-tetrahydro-1-1-biphenyl-2-yl-methyl-piperazin-1-yl-n-3-nitro-4-tetrahydro-2h-pyran-4-yl-methyl-amino-phenyl-sulfonyl-benzamide-pa220361024
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PA 22 0361024

2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-6-hydroxy-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide


  • Catalogue No.:PA 22 0361024

  • CAS :

    2573767-96-9

  • Molecular Formula : C45H50ClN7O8S

  • Molecular Weight : 884.45