Lys-Nε-SPDB-DM4

In House Impurity

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Catalogue number:	PA 40 0571001
Chemical name:	Lys-Nε-SPDB-DM4
CAS Number:	1280215-91-9
Category:	aromatics,chiral standards,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate
Synonyms:	Maytansine, N2′-[4-[[4-[[(5S)-5-amino-5-carboxypentyl]amino]-4-oxobutyl]dithio]-4-methyl-1-oxopentyl]-N2′-deacetyl-; N6-(4-((5-(((S)-1-(((14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-2-methyl-5-oxopentan-2-yl)disulfaneyl)butanoyl)-L-lysine;
Molecular form:	C₄₈H₇₂ClN₅O₁₃S₂
Appearance:	Solid
Mol. Weight:	1026.70
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Lys-Nε-SPDB-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody agent conjugate (ADC)