DM1-SMe

In House Impurity

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Catalogue number:	PA 40 0571011
Chemical name:	DM1-SMe
CAS Number:	138148-68-2
Category:	pharmaceutical standards,Intermediates,Fine Chemicals,Antibody Drug Conjugate
Synonyms:	(14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methyldisulfaneyl)propanoyl)-L-alaninate; Maytansine, N2′-deacetyl-N2′-[3-(methyldithio)-1-oxopropyl]-; 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv;
Molecular form:	C₃₆H₅₀ClN₃O₁₀S₂
Appearance:	Solid
Mol. Weight:	784.38
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901. DM1-SMe is the microtubule inhibitor and can be used as the ADC cytotoxin