| Catalogue number: | PA 40 0571012 |
| Chemical name: | Maytansinoid B |
CAS Number: |
1628543-40-7 |
| Category: | pharmaceutical standards,Intermediates,Fine Chemicals,Antibody Drug Conjugate |
| Synonyms: | (14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methylamino)propanoyl)-L-alaninate; Maytansine, N2′-deacetyl-N2′-[3-(methylamino)-1-oxopropyl]-; |
| Molecular form: | C36H51ClN4O10 |
| Appearance: | Solid |
| Mol. Weight: | 735.27 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoid B can be used to conjugates with antibodies to form antibody-drug conjugates (ADCs). Maytansinoids are known as antimitotic agents, binding to tubulin and inhibiting microtubule assembly. Maytansinoids induces G2/M arrest in the cell cycle to induce apoptosis |
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