apixaban and its Impurities

Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation.. Reference standards of Apixaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 43 results for apixaban Impurities
PA 28 11000

Apixaban - API

Apixaban


  • Catalogue No.:PA 28 11000

  • CAS :

    503612-47-3

  • Molecular Formula : C25H25N5O4

  • Molecular Weight : 459.50

PA 28 11510

O-Desmethyl Apixaban

O-Desmethyl Apixaban


  • Catalogue No.:PA 28 11510

  • CAS :

    503612-76-8

  • Molecular Formula : C24H23N5O4

  • Molecular Weight : 445.47

PA 28 11520

O-Desmethyl Apixaban Sulfate

O-Desmethyl Apixaban Sulfate


  • Catalogue No.:PA 28 11520

  • CAS :

    1118765-14-2

  • Molecular Formula : C24H23N5O7S

  • Molecular Weight : 525.53

PA 28 11530

Hydroxy Apixaban

Hydroxy Apixaban


  • Catalogue No.:PA 28 11530

  • CAS :

    NA

  • Molecular Formula : C25H25N5O5

  • Molecular Weight : 475.5

PA 28 11540

Hydroxy O-Demethyl Apixaban

Hydroxy O-Demethyl Apixaban


  • Catalogue No.:PA 28 11540

  • CAS :

    NA

  • Molecular Formula : C24H23N5O5

  • Molecular Weight : 461.47

PA 28 11550

Hydroxy O-Demethyl Apixaban Sulfate

Hydroxy O-Demethyl Apixaban Sulfate


  • Catalogue No.:PA 28 11550

  • CAS :

    NA

  • Molecular Formula : C24H23N5O8S

  • Molecular Weight : 541.53

PA 28 11560

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid

3-Carbamoyl-1-(4-methoxyphenyl)-4-(2-(4-(2-oxopiperidin-1-yl)phenylamino)ethyl)-1H-pyrazole-5-carboxylic Acid


  • Catalogue No.:PA 28 11560

  • CAS :

    NA

  • Molecular Formula : C25H27N5O5

  • Molecular Weight : 477.51

PA 28 11570

Apixaban Carboxylic Acid Impurity

Apixaban Carboxylic Acid Impurity


  • Catalogue No.:PA 28 11570

  • CAS :

    503614-92-4

  • Molecular Formula : C25H24N4O5

  • Molecular Weight : 460.48

PA 28 11580

6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid

6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid


  • Catalogue No.:PA 28 11580

  • CAS :

    1704504-93-7

  • Molecular Formula : C20H18N4O4

  • Molecular Weight : 378.38

PA 28 11590

Apixaban Amino Acid Impurity

Apixaban Amino Acid Impurity


  • Catalogue No.:PA 28 11590

  • CAS :

    NA

  • Molecular Formula : C25H27N5O5

  • Molecular Weight : 477.51

PA 28 11600

Methyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Methyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 11600

  • CAS :

    1466571-07-2

  • Molecular Formula : C21H20N4O4

  • Molecular Weight : 392.41

PA 28 11610

Apixaban Methyl Ester Impurity

Apixaban Methyl Ester Impurity


  • Catalogue No.:PA 28 11610

  • CAS :

    1074365-84-6

  • Molecular Formula : C26H26N4O5

  • Molecular Weight : 474.51

PA 28 11620

Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate

Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate


  • Catalogue No.:PA 28 11620

  • CAS :

    NA

  • Molecular Formula : C26H29N5O5

  • Molecular Weight : 491.54

PA 28 11630

Apixaban Dehydro Impurity

Apixaban Dehydro Impurity


  • Catalogue No.:PA 28 11630

  • CAS :

    1074549-89-5

  • Molecular Formula : C25H23N5O4

  • Molecular Weight : 457.48

PA 28 11640

Apixaban Carboxylic Acid O-Desmethyl Impurity

Apixaban Carboxylic Acid O-Desmethyl Impurity


  • Catalogue No.:PA 28 11640

  • CAS :

    NA

  • Molecular Formula : C24H22N4O5

  • Molecular Weight : 446.46

PA 28 11650

Apixaban Chloro Impurity

Apixaban Chloro Impurity


  • Catalogue No.:PA 28 11650

  • CAS :

    NA

  • Molecular Formula : C24H22ClN5O3

  • Molecular Weight : 463.92

PA 28 11660

Apixaban Ethyl Ester Impurity

Apixaban Ethyl Ester Impurity


  • Catalogue No.:PA 28 11660

  • CAS :

    503614-91-3

  • Molecular Formula : C27H28N4O5

  • Molecular Weight : 488.54

PA 28 11670

Apixaban Isopropyl Ester Impurity

Apixaban Isopropyl Ester Impurity


  • Catalogue No.:PA 28 11670

  • CAS :

    NA

  • Molecular Formula : C28H30N4O5

  • Molecular Weight : 502.56

PA 28 11680

6-(4-((5-Amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

6-(4-((5-Amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11680

  • CAS :

    2187409-01-2

  • Molecular Formula : C25H28N6O4

  • Molecular Weight : 476.53

PA 28 11690

1-(4-Methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-6-(4-(5-methyl-2-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11690

  • CAS :

    1686149-74-5

  • Molecular Formula : C26H27N5O4

  • Molecular Weight : 473.52

PA 28 11700

1-(4-Methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-6-(4-(2-methyl-6-oxopiperidin-1-yl)phenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11700

  • CAS :

    NA

  • Molecular Formula : C26H27N5O4

  • Molecular Weight : 473.52

PA 28 11710

(E)-Ethyl 2-(2-(4-methoxyphenyl)hydrazono)propanoate

(E)-Ethyl 2-(2-(4-methoxyphenyl)hydrazono)propanoate


  • Catalogue No.:PA 28 11710

  • CAS :

    4792-57-8

  • Molecular Formula : C12H16N2O3

  • Molecular Weight : 236.27

PA 28 11720

3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one


  • Catalogue No.:PA 28 11720

  • CAS :

    536760-29-9

  • Molecular Formula : C11H9ClN2O3

  • Molecular Weight : 252.65

PA 28 11730

5-​Chloro-​4-​methylpentanoyl Chloride

5-​Chloro-​4-​methylpentanoyl Chloride


  • Catalogue No.:PA 28 11730

  • CAS :

    813452-05-0

  • Molecular Formula : C6H10Cl2O

  • Molecular Weight : 169.05

PA 28 11740

5-​Chloro-hexanoyl Chloride

5-​Chloro-hexanoyl Chloride


  • Catalogue No.:PA 28 11740

  • CAS :

    99585-01-0

  • Molecular Formula : C6H10Cl2O

  • Molecular Weight : 169.05

PA 28 11750

1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxoazepan-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxoazepan-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11750

  • CAS :

    NA

  • Molecular Formula : C26H27N5O4

  • Molecular Weight : 473.52

PA 28 11760

1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopyrrolidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopyrrolidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11760

  • CAS :

    NA

  • Molecular Formula : C24H23N5O4

  • Molecular Weight : 445.47

PA 28 11770

6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11770

  • CAS :

    1423803-24-0

  • Molecular Formula : C20H19N5O3

  • Molecular Weight : 377.4

PA 28 11780

1-(4-Methoxyphenyl)-3-(morpholine-4-carbonyl)-6-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one

1-(4-Methoxyphenyl)-3-(morpholine-4-carbonyl)-6-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one


  • Catalogue No.:PA 28 11780

  • CAS :

    NA

  • Molecular Formula : C29H31N5O5

  • Molecular Weight : 529.59

PA 28 11790

(E)-1,2-Bis(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)diazene oxide

(E)-1,2-Bis(4-(3-carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)diazene oxide


  • Catalogue No.:PA 28 11790

  • CAS :

    NA

  • Molecular Formula : C40H34N10O7

  • Molecular Weight : 766.76

PA 28 11800

5-Chloro-N-(4-(3-morpholino-2-oxo-5,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide

5-Chloro-N-(4-(3-morpholino-2-oxo-5,6-dihydropyridin-1(2H)-yl)phenyl)pentanamide


  • Catalogue No.:PA 28 11800

  • CAS :

    NA

  • Molecular Formula : C20H26ClN3O3

  • Molecular Weight : 391.89

PA 28 11810

Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 11810

  • CAS :

    1421823-20-2

  • Molecular Formula : C27H29ClN4O5

  • Molecular Weight : 525

PA 28 11820

(Z)-Ethyl 2-chloro-2-(2-(3-methoxyphenyl)hydrazono)acetate

(Z)-Ethyl 2-chloro-2-(2-(3-methoxyphenyl)hydrazono)acetate


  • Catalogue No.:PA 28 11820

  • CAS :

    405872-78-8

  • Molecular Formula : C11H13ClN2O3

  • Molecular Weight : 256.69

PA 28 11830

N-Formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

N-Formyl-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11830

  • CAS :

    1351611-14-7

  • Molecular Formula : C26H25N5O5

  • Molecular Weight : 487.51

PA 28 11840

Ethyl-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate

Ethyl-2-chloro-2-[2-(4-methoxyphenyl)hydrazin-1-ylidene]acetate


  • Catalogue No.:PA 28 11840

  • CAS :

    1644619-42-0

  • Molecular Formula : C11H13ClN2O3

  • Molecular Weight : 256.69

PA 28 11850

3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one

3-(Morpholinyl)-N-(4-nitrophenyl)-5,6-dihydropyridin-2-one


  • Catalogue No.:PA 28 11850

  • CAS :

    503615-03-0

  • Molecular Formula : C15H17N3O4

  • Molecular Weight : 303.31

PAI 01 012010

5-Methyltetrahydro-2H-pyran-2-one

5-Methyltetrahydro-2H-pyran-2-one


  • Catalogue No.:PAI 01 012010

  • CAS :

    NA

  • Molecular Formula : C6H10O2

  • Molecular Weight : 114.14

PAI 01 012020

5-Hydroxy-4-methylpentanoic acid

5-Hydroxy-4-methylpentanoic acid


  • Catalogue No.:PAI 01 012020

  • CAS :

    105025-31-8

  • Molecular Formula : C6H12O3

  • Molecular Weight : 132.16

PA 28 11890

Apixaban Dimer

Apixaban Dimer


  • Catalogue No.:PA 28 11890

  • CAS :

    1998079-11-0

  • Molecular Formula : C40H34N10O6

  • Molecular Weight : 750.78

PA 28 11900

Apixaban N-Oxide Dimer

Apixaban N-Oxide Dimer


  • Catalogue No.:PA 28 11900

  • CAS :

    1998079-12-1

  • Molecular Formula : C40H34N10O7

  • Molecular Weight : 766.78

PA 28 11910

7-Oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

7-Oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide


  • Catalogue No.:PA 28 11910

  • CAS :

    1801881-17-3

  • Molecular Formula : C24H23N5O3

  • Molecular Weight : 429.48

PA 28 11920

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one


  • Catalogue No.:PA 28 11920

  • CAS :

    545445-44-1

  • Molecular Formula : C20H25N3O3

  • Molecular Weight : 355.44

PA 28 0111000

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)pyridin-2(1H)-one

3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)pyridin-2(1H)-one


  • Catalogue No.:PA 28 0111000

  • CAS :

    NA

  • Molecular Formula : C20H23N3O3

  • Molecular Weight : 353.42