geldanamycin and its Impurities
Geldanamycin is a 1,4-benzoquinone ansamycin antitumor antibiotic that inhibits the function of Hsp90 by binding to the unusual ADP/ATP-binding pocket of the protein. Reference standards of Geldanamycin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
(4Z,6E,8S,9S,10E,12S,13R,14S,16R)-19-((3-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanamido)propyl)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
(4Z,6E,8S,9S,10E,12S,13R,14S,16R)-19-((3-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanamido)propyl)amino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Catalogue No.:PA 07 0661003
CAS :
256337-10-7
Molecular Formula : C39H53N5O11
Molecular Weight : 767.88
