Ibrutinib-impurities | Pharmaffiliates

ibrutinib and its Impurities

Ibrutinib is used to treat chronic lymphocytic leukemia Waldenström's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease. It is a small molecule drug. Reference standards of Ibrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 44 results for ibrutinib Impurities
PA 09 27000

Ibrutinib - API

Ibrutinib

  • Catalogue No.:PA 09 27000

  • CAS :

    936563-96-1

  • Molecular Formula : C25H24N6O2

  • Molecular Weight : 440.50

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PA 09 27510

1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

  • Catalogue No.:PA 09 27510

  • CAS :

    NA

  • Molecular Formula : C47H46N12O3

  • Molecular Weight : 826.95

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PA 09 27520

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate

  • Catalogue No.:PA 09 27520

  • CAS :

    NA

  • Molecular Formula : C28H28N6O4

  • Molecular Weight : 512.56

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PA 09 27530

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one

  • Catalogue No.:PA 09 27530

  • CAS :

    2031255-23-7

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 880.99

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PA 09 27540

(S)-Ibrutinib

(S)-Ibrutinib

  • Catalogue No.:PA 09 27540

  • CAS :

    936563-97-2

  • Molecular Formula : C25H24N6O2

  • Molecular Weight : 440.5

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PA 09 27550

Dihydrodiol Ibrutinib

Dihydrodiol Ibrutinib

  • Catalogue No.:PA 09 27550

  • CAS :

    1226872-27-0

  • Molecular Formula : C25H26N6O4

  • Molecular Weight : 474.51

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PA 09 27560

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

  • Catalogue No.:PA 09 27560

  • CAS :

    1022150-12-4

  • Molecular Formula : C22H22N6O

  • Molecular Weight : 386.45

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PA 09 27570

(E)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-hydroxyprop-2-en-1-one

(E)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-hydroxyprop-2-en-1-one

  • Catalogue No.:PA 09 27570

  • CAS :

    NA

  • Molecular Formula : C25H24N6O3

  • Molecular Weight : 456.5

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PA 09 27580

Namino-{3-[(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]-propionyl} Ibrutinib

Namino-{3-[(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]-propionyl} Ibrutinib

  • Catalogue No.:PA 09 27580

  • CAS :

    NA

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 880.99

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PA STI 052370

Ibrutinib-d5

Ibrutinib-d5

  • Catalogue No.:PA STI 052370

  • CAS :

    1553977-17-5

  • Molecular Formula : C25H19D5N6O2

  • Molecular Weight : 445.53

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PA STI 052380

(S)-Ibrutinib-d5

(S)-Ibrutinib-d5

  • Catalogue No.:PA STI 052380

  • CAS :

    NA

  • Molecular Formula : C25H19D5N6O2

  • Molecular Weight : 445.53

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PAI 09 007010

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

  • Catalogue No.:PAI 09 007010

  • CAS :

    151266-23-8

  • Molecular Formula : C5H4IN5

  • Molecular Weight : 261.03

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PAI 09 007020

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

  • Catalogue No.:PAI 09 007020

  • CAS :

    330786-24-8

  • Molecular Formula : C17H13N5O

  • Molecular Weight : 303.33

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PAI 09 007030

(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate

(R)-tert-Butyl 3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate

  • Catalogue No.:PAI 09 007030

  • CAS :

    1022150-11-3

  • Molecular Formula : C27H30N6O3

  • Molecular Weight : 486.58

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PAI 09 007040

Ethyl (R)-3-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanoate

Ethyl (R)-3-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanoate

  • Catalogue No.:PAI 09 007040

  • CAS :

    NA

  • Molecular Formula : C27H30N6O3

  • Molecular Weight : 486.58

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PAI 09 007050

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanoic Acid

(R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanoic Acid

  • Catalogue No.:PAI 09 007050

  • CAS :

    NA

  • Molecular Formula : C25H26N6O3

  • Molecular Weight : 458.52

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PAI 09 007060

Methyl (R)-3-((1-(1-acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)propanoate

Methyl (R)-3-((1-(1-acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)propanoate

  • Catalogue No.:PAI 09 007060

  • CAS :

    NA

  • Molecular Formula : C29H30N6O4

  • Molecular Weight : 526.60

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PAI 09 007070

N6-(2-Carboxyethyl) Ibrutinib

N6-(2-Carboxyethyl) Ibrutinib

  • Catalogue No.:PAI 09 007070

  • CAS :

    NA

  • Molecular Formula : C28H28N6O4

  • Molecular Weight : 512.57

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PAI 09 007080

4-Aminopyrazolo[3,4-d]pyrimidine

4-Aminopyrazolo[3,4-d]pyrimidine

  • Catalogue No.:PAI 09 007080

  • CAS :

    2380-63-4

  • Molecular Formula : C5H5N5

  • Molecular Weight : 135.13

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PA 09 27590

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one

  • Catalogue No.:PA 09 27590

  • CAS :

    NA

  • Molecular Formula : C26H28N6O3

  • Molecular Weight : 472.55

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PA 09 27600

1-((R)-3-(4-((3-((S)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

1-((R)-3-(4-((3-((S)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

  • Catalogue No.:PA 09 27600

  • CAS :

    NA

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 881.01

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PA 09 27610

(R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

(R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

  • Catalogue No.:PA 09 27610

  • CAS :

    NA

  • Molecular Formula : C42H37N11O3

  • Molecular Weight : 743.83

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PA 09 27620

N6-Acryloyl Ibrutinib

N6-Acryloyl Ibrutinib

  • Catalogue No.:PA 09 27620

  • CAS :

    2031255-27-1

  • Molecular Formula : C28H26N6O3

  • Molecular Weight : 494.56

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PA 09 27630

(R)-1-(3-(4-Hydroxy-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

(R)-1-(3-(4-Hydroxy-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

  • Catalogue No.:PA 09 27630

  • CAS :

    NA

  • Molecular Formula : C25H23N5O3

  • Molecular Weight : 441.49

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PA 09 27640

(R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine 2-oxide

(R)-1-(1-Acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine 2-oxide

  • Catalogue No.:PA 09 27640

  • CAS :

    NA

  • Molecular Formula : C25H24N6O3

  • Molecular Weight : 456.51

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PA 09 27650

1-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-((S)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

1-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-((S)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

  • Catalogue No.:PA 09 27650

  • CAS :

    NA

  • Molecular Formula : C47H46N12O3

  • Molecular Weight : 826.97

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PA 09 27660

Ibrutinib Hydroxy

Ibrutinib Hydroxy

  • Catalogue No.:PA 09 27660

  • CAS :

    2031255-24-8

  • Molecular Formula : C25H23N5O3

  • Molecular Weight : 441.49

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PA 09 27670

N-(1-(1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanamide

N-(1-(1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanamide

  • Catalogue No.:PA 09 27670

  • CAS :

    2171352-31-9

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 881.01

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PA 09 27680

(R)-4-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)pent-4-enoic Acid

(R)-4-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)pent-4-enoic Acid

  • Catalogue No.:PA 09 27680

  • CAS :

    NA

  • Molecular Formula : C28H28N6O4

  • Molecular Weight : 512.57

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PA 09 27690

1-((R)-3-(5-(3-((S)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

1-((R)-3-(5-(3-((S)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

  • Catalogue No.:PA 09 27690

  • CAS :

    NA

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 881.01

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PA 09 0271000

(R)-1-Boc-3-Hydroxypiperidine

(R)-1-Boc-3-Hydroxypiperidine

  • Catalogue No.:PA 09 0271000

  • CAS :

    143900-43-0

  • Molecular Formula : C10H19NO3

  • Molecular Weight : 201.27

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PA 09 0271001

Ibrutinib-biotin

Ibrutinib-biotin

  • Catalogue No.:PA 09 0271001

  • CAS :

    1599432-18-4

  • Molecular Formula : C56H80N12O9S

  • Molecular Weight : 1097.39

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PA 09 0271002

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethan-1-one

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethan-1-one

  • Catalogue No.:PA 09 0271002

  • CAS :

    NA

  • Molecular Formula : C24H24N6O2

  • Molecular Weight : 428.5

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PA 09 0271003

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one

(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one

  • Catalogue No.:PA 09 0271003

  • CAS :

    1288338-96-4

  • Molecular Formula : C25H25ClN6O2

  • Molecular Weight : 476.97

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PA 09 0271004

(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine

(R)-N-(3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,1,1-triphenyl-l5-phosphanimine

  • Catalogue No.:PA 09 0271004

  • CAS :

    NA

  • Molecular Formula : C40H35N6OP

  • Molecular Weight : 646.73

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PA 09 0271005

(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

(R)-1-(3-(3-(4-Phenoxyphenyl)-4-((triphenyl-l5-phosphanylidene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

  • Catalogue No.:PA 09 0271005

  • CAS :

    NA

  • Molecular Formula : C43H37N6O2P

  • Molecular Weight : 700.78

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PA 09 0271006

1-((S)-3-(2-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-2,4-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

1-((S)-3-(2-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-2,4-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

  • Catalogue No.:PA 09 0271006

  • CAS :

    NA

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 881.01

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PA 09 0271007

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride

(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Dihydrochloride

  • Catalogue No.:PA 09 0271007

  • CAS :

    1701403-10-2

  • Molecular Formula : C22H24Cl2N6O

  • Molecular Weight : 459.38

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PA 09 0271008

Ibrutinib N-Oxide impurity

Ibrutinib N-Oxide impurity

  • Catalogue No.:PA 09 0271008

  • CAS :

    NA

  • Molecular Formula : C25H24N6O3

  • Molecular Weight : 456.5

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PA 09 0271009

(R)-N-Desacryloyl N-Propionyl Ibrutinib

(R)-N-Desacryloyl N-Propionyl Ibrutinib

  • Catalogue No.:PA 09 0271009

  • CAS :

    1839099-22-7

  • Molecular Formula : C25H26N6O2

  • Molecular Weight : 442.52

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PA 09 0271012

1-((R)-3-(5-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

1-((R)-3-(5-(3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)-4-imino-3-(4-phenoxyphenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

  • Catalogue No.:PA 09 0271012

  • CAS :

    2417548-76-4

  • Molecular Formula : C50H48N12O4

  • Molecular Weight : 881.01

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PA STI 088988

1-((R)-3-(4-Amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one

1-((R)-3-(4-Amino-3-(4-(phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one

  • Catalogue No.:PA STI 088988

  • CAS :

    2068022-09-1

  • Molecular Formula : C25H21D5N6O4

  • Molecular Weight : 479.55

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PA 09 0271010

1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

1-Methyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

  • Catalogue No.:PA 09 0271010

  • CAS :

    2213398-75-3

  • Molecular Formula : C18H15N5O

  • Molecular Weight : 317.35

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PA 09 0271011

1,1'-(((Oxybis(4,1-phenylene))bis(4-amino-1H-pyrazolo[3,4-d]pyrimidine-3,1-diyl))bis(piperidine-3,1-diyl))bis(prop-2-en-1-one)

1,1'-(((Oxybis(4,1-phenylene))bis(4-amino-1H-pyrazolo[3,4-d]pyrimidine-3,1-diyl))bis(piperidine-3,1-diyl))bis(prop-2-en-1-one)

  • Catalogue No.:PA 09 0271011

  • CAS :

    NA

  • Molecular Formula : C38H38N12O3

  • Molecular Weight : 710.8

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