obeticholic acid and its Impurities
Obeticholic Acid is used to treat a number of liver diseases. Obeticholic acid is a farnesoid-X receptor agonist. Obeticholic acid is a semi-synthetic bile acid.Reference standards of Obeticholic Acid API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


Methyl (R)-4-((3R,5R,8S,9S,10R,13R,14S,17R)-3-acetoxy-6-ethylidene-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Methyl (R)-4-((3R,5R,8S,9S,10R,13R,14S,17R)-3-acetoxy-6-ethylidene-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Catalogue No.:PA 15 38630
CAS :
2241648-47-3
Molecular Formula : C29H44O5
Molecular Weight : 472.67


Methyl (R)-4-((3R,5S,6S,8S,9S,10S,13R,14S,17R)-3-acetoxy-6-ethyl-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Methyl (R)-4-((3R,5S,6S,8S,9S,10S,13R,14S,17R)-3-acetoxy-6-ethyl-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Catalogue No.:PA 15 38640
CAS :
1831863-19-4
Molecular Formula : C29H46O5
Molecular Weight : 474.68


(R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,E)-6-Ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid
(R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,E)-6-Ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid
Catalogue No.:PA 15 0381000
CAS :
1947343-07-8
Molecular Formula : C26H42O4
Molecular Weight : 418.62


(R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,Z)-6-Ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid
(R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,Z)-6-Ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid
Catalogue No.:PA 15 0381001
CAS :
1885104-64-2
Molecular Formula : C26H42O4
Molecular Weight : 418.61


Ethyl (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Ethyl (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Catalogue No.:PA 15 0381005
CAS :
459789-98-1
Molecular Formula : C28H48O4
Molecular Weight : 448.69


(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-3-Acetoxy-6-ethyl-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid
(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-3-Acetoxy-6-ethyl-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid
Catalogue No.:PA 15 0381007
CAS :
2055651-18-6
Molecular Formula : C28H46O5
Molecular Weight : 462.67


Ethyl (R)-4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Ethyl (R)-4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Catalogue No.:PA 15 0381009
CAS :
459789-97-0
Molecular Formula : C28H46O4
Molecular Weight : 446.67