Irinotecan-impurities | Pharmaffiliates

irinotecan

Irinotecan main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. It is sold under the brand name Camptosar. Reference standards of Irinotecan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

PA 09 16010

Irinotecan - Impurity A


  • Catalogue No.:PA 09 16010

  • CAS :

    103816-16-6

  • Molecular Formula : C31H34N4O6

  • Molecular Weight : 558.62

PA 09 16030

Irinotecan - Impurity C


  • Catalogue No.:PA 09 16030

  • CAS :

    947687-02-7

  • Molecular Formula : C35H42N4O6

  • Molecular Weight : 614.73

PA 09 16530

Irinotecan - Impurity M


  • Catalogue No.:PA 09 16530

  • CAS :

    185336-12-3

  • Molecular Formula : C33H38N4O7

  • Molecular Weight : 602.68

PA 09 16540

Irinotecan 2-Hydroxy Impurity


  • Catalogue No.:PA 09 16540

  • CAS :

    1346597-39-4

  • Molecular Formula : C33H38N4O7

  • Molecular Weight : 602.68

PA 09 16560

Irinotecan - Impurity E


  • Catalogue No.:PA 09 16560

  • CAS :

    86639-52-3

  • Molecular Formula : C22H20N2O5

  • Molecular Weight : 392.40

PA 09 16570

4-Ethyl-4-hydroxy-11-isopropyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate;


  • Catalogue No.:PA 09 16570

  • CAS :

    NA

  • Molecular Formula : C34H40N4O6

  • Molecular Weight : 600.7

PA 09 16580

rac-Desmethyl Irinotecan Hydrochloride


  • Catalogue No.:PA 09 16580

  • CAS :

    NA

  • Molecular Formula : C32H37ClN4O6

  • Molecular Weight : 609.11

PA STI 027330

11-Desethyl Irinotecan-d10


  • Catalogue No.:PA STI 027330

  • CAS :

    NA

  • Molecular Formula : C31H24D10N4O6

  • Molecular Weight : 568.69

PA STI 038750

7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3


  • Catalogue No.:PA STI 038750

  • CAS :

    1217816-76-6

  • Molecular Formula : C33H35D3N4O8

  • Molecular Weight : 621.70

PA STI 038760

7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3


  • Catalogue No.:PA STI 038760

  • CAS :

    1217625-98-3

  • Molecular Formula : C28H27D3N4O6

  • Molecular Weight : 521.58

PA STI 049410

2-Hydroxy Irinotecan-d10


  • Catalogue No.:PA STI 049410

  • CAS :

    1346597-30-5

  • Molecular Formula : C33H28D10N4O7

  • Molecular Weight : 612.74

PA 09 16070

Irinotecan - Impurity G


  • Catalogue No.:PA 09 16070

  • CAS :

    947687-01-6

  • Molecular Formula : C24H24N2O5

  • Molecular Weight : 420.47

PA 09 16122

Irinotecan - Impurity L (Freebase)


  • Catalogue No.:PA 09 16122

  • CAS :

    1255644-71-3

  • Molecular Formula : C33H38N4O6

  • Molecular Weight : 586.69

PA 09 0151000

1-(2-Amino-5-hydroxyphenyl)propan-1-one


  • Catalogue No.:PA 09 0151000

  • CAS :

    35364-15-9

  • Molecular Formula : C9H11NO2

  • Molecular Weight : 165.19

PA STI 088709

Irinotecan-d10 Hydrochloride (Major)


  • Catalogue No.:PA STI 088709

  • CAS :

    718612-62-5

  • Molecular Formula : C33H29D10ClN4O6

  • Molecular Weight : 633.21

PA 09 0151001

(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 2'-ethoxy-[1,4'-bipiperidine]-1'-carboxylate


  • Catalogue No.:PA 09 0151001

  • CAS :

    NA

  • Molecular Formula : C35H42N4O7

  • Molecular Weight : 630.74

PA 09 0151002

(4S)-4,11-Diethyl-4,9,12-trihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione


  • Catalogue No.:PA 09 0151002

  • CAS :

    NA

  • Molecular Formula : C22H20N2O6

  • Molecular Weight : 408.41

PA 09 0151003

2'-Ethoxy-[1,4'-bipiperidine]-1'-carbonyl Chloride


  • Catalogue No.:PA 09 0151003

  • CAS :

    NA

  • Molecular Formula : C13H23ClN2O2

  • Molecular Weight : 274.79

PA 09 0151004

2'-hydroxy-[1,4'-bipiperidine]-1'-carbonyl chloride


  • Catalogue No.:PA 09 0151004

  • CAS :

    NA

  • Molecular Formula : C11H19ClN2O2

  • Molecular Weight : 246.74

PA 09 0151005

SN-38 Tri-O-acetyl-β-D-glucuronic acid methyl ester


  • Catalogue No.:PA 09 0151005

  • CAS :

    121098-77-9

  • Molecular Formula : C35H36N2O14

  • Molecular Weight : 708.67