irinotecan
Irinotecan main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. It is sold under the brand name Camptosar. Reference standards of Irinotecan API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[catalogue_number] => PA 09 16570
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[chemical_name] =>
[weight] => 600.7
[form] => C34H40N4O6
[cas] => NA
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4-Ethyl-4-hydroxy-11-isopropyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate;
stdClass Object
(
[pname] => rac-Desmethyl Irinotecan Hydrochloride
[catalogue_number] => PA 09 16580
[category_ids] => ,82,78,76,75,70,69,
[chemical_name] =>
[weight] => 609.11
[form] => C32H37ClN4O6
[cas] => NA
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rac-Desmethyl Irinotecan Hydrochloride
Catalogue No.:PA 09 16580
Molecular Formula : C32H37ClN4O6
Molecular Weight : 609.11
stdClass Object
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[pname] => 10-O-Acetyl SN-38-d3
[catalogue_number] => PA STI 003450
[category_ids] => ,69,76,78,70,82,98,
[chemical_name] =>
[weight] => 437.46
[form] => C24H19D3N2O6
[cas] => NA
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Catalogue No.:PA STI 003450
Molecular Formula : C24H19D3N2O6
Molecular Weight : 437.46
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[catalogue_number] => PA STI 038750
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[weight] => 621.70
[form] => C33H35D3N4O8
[cas] => 1217816-76-6
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7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3
Catalogue No.:PA STI 038750
Molecular Formula : C33H35D3N4O8
Molecular Weight : 621.70
stdClass Object
(
[pname] => 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3
[catalogue_number] => PA STI 038760
[category_ids] => ,76,75,78,70,82,98,
[chemical_name] =>
[weight] => 521.58
[form] => C28H27D3N4O6
[cas] => 1217625-98-3
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7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3
Catalogue No.:PA STI 038760
Molecular Formula : C28H27D3N4O6
Molecular Weight : 521.58
stdClass Object
(
[pname] => 1-(2-Amino-5-hydroxyphenyl)propan-1-one
[catalogue_number] => PA 09 0151000
[category_ids] => ,75,76,70,78,82,
[chemical_name] =>
[weight] => 165.19
[form] => C9H11NO2
[cas] => 35364-15-9
[pslug] => 35364-15-9-1-2-amino-5-hydroxyphenyl-propan-1-one-pa090151000
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1-(2-Amino-5-hydroxyphenyl)propan-1-one
Catalogue No.:PA 09 0151000
Molecular Formula : C9H11NO2
Molecular Weight : 165.19
stdClass Object
(
[pname] => 4-Piperidinopiperidine-1-carbonyl Chloride
[catalogue_number] => PA 09 0161000
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[weight] => 230.74
[form] => C11H19ClN2O
[cas] => 103816-19-9
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4-Piperidinopiperidine-1-carbonyl Chloride
Catalogue No.:PA 09 0161000
Molecular Formula : C11H19ClN2O
Molecular Weight : 230.74
stdClass Object
(
[pname] => Irinotecan-d10 Hydrochloride (Major)
[catalogue_number] => PA STI 088709
[category_ids] => ,98,69,123,81,75,76,78,70,82,
[chemical_name] =>
[weight] => 633.21
[form] => C33H29D10ClN4O6
[cas] => 718612-62-5
[pslug] => 718612-62-5-irinotecan-d10-hydrochloride-major-pasti088709
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Irinotecan-d10 Hydrochloride (Major)
Catalogue No.:PA STI 088709
Molecular Formula : C33H29D10ClN4O6
Molecular Weight : 633.21
stdClass Object
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[pname] => (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 2'-ethoxy-[1,4'-bipiperidine]-1'-carboxylate
[catalogue_number] => PA 09 0151001
[category_ids] => ,70,75,76,78,82,
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[weight] => 630.74
[form] => C35H42N4O7
[cas] => NA
[pslug] => S-4-11-diethyl-4-hydroxy-3-14-dioxo-3-4-12-14-tetrahydro-1h-pyrano-3-4-6-7-indolizino-1-2-b-quinolin-9-yl-2-ethoxy-1-4-bipiperidine-1-carboxylate-pa090151001
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(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 2'-ethoxy-[1,4'-bipiperidine]-1'-carboxylate
Catalogue No.:PA 09 0151001
Molecular Formula : C35H42N4O7
Molecular Weight : 630.74
stdClass Object
(
[pname] => (4S)-4,11-Diethyl-4,9,12-trihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
[catalogue_number] => PA 09 0151002
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 408.41
[form] => C22H20N2O6
[cas] => 200619-21-2
[pslug] => 200619-21-2-4s-4-11-diethyl-4-9-12-trihydroxy-1-12-dihydro-14h-pyrano-3-4-6-7-indolizino-1-2-b-quinoline-3-14-4h-dione-pa090151002
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(4S)-4,11-Diethyl-4,9,12-trihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
Catalogue No.:PA 09 0151002
Molecular Formula : C22H20N2O6
Molecular Weight : 408.41
stdClass Object
(
[pname] => 2'-Ethoxy-[1,4'-bipiperidine]-1'-carbonyl Chloride
[catalogue_number] => PA 09 0151003
[category_ids] => ,78,75,70,76,82,
[chemical_name] =>
[weight] => 274.79
[form] => C13H23ClN2O2
[cas] => NA
[pslug] => 2-ethoxy-1-4-bipiperidine-1-carbonyl-chloride-pa090151003
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2'-Ethoxy-[1,4'-bipiperidine]-1'-carbonyl Chloride
Catalogue No.:PA 09 0151003
Molecular Formula : C13H23ClN2O2
Molecular Weight : 274.79
stdClass Object
(
[pname] => 2'-hydroxy-[1,4'-bipiperidine]-1'-carbonyl chloride
[catalogue_number] => PA 09 0151004
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 246.74
[form] => C11H19ClN2O2
[cas] => NA
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2'-hydroxy-[1,4'-bipiperidine]-1'-carbonyl chloride
Catalogue No.:PA 09 0151004
Molecular Formula : C11H19ClN2O2
Molecular Weight : 246.74
stdClass Object
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[pname] => SN-38 Tri-O-acetyl-β-D-glucuronic acid methyl ester
[catalogue_number] => PA 09 0151005
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[weight] => 708.67
[form] => C35H36N2O14
[cas] => 121098-77-9
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SN-38 Tri-O-acetyl-β-D-glucuronic acid methyl ester
Catalogue No.:PA 09 0151005
Molecular Formula : C35H36N2O14
Molecular Weight : 708.67
stdClass Object
(
[pname] => (S)-12-Ethyl-8-(hydroxymethyl)-7-(1-hydroxypropyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate
[catalogue_number] => PA 09 0151006
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 560.7
[form] => C32H40N4O5
[cas] => 185304-41-0
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(S)-12-Ethyl-8-(hydroxymethyl)-7-(1-hydroxypropyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate
stdClass Object
(
[pname] => Irinotecan - Impurity G (Hydrochloride Salt)
[catalogue_number] => PA 09 0150070
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 456.92
[form] => C24H25ClN2O5
[cas] => NA
[pslug] => irinotecan-impurity-g-hydrochloride-salt-pa090150070
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Irinotecan - Impurity G (Hydrochloride Salt)
Catalogue No.:PA 09 0150070
Molecular Formula : C24H25ClN2O5
Molecular Weight : 456.92
stdClass Object
(
[pname] => Sodium (S)-2-(12-ethyl-8-(hydroxymethyl)-2-oxido-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate
[catalogue_number] => PA 09 0151007
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 454.39
[form] => C22H20N2Na2O6
[cas] => NA
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Sodium (S)-2-(12-ethyl-8-(hydroxymethyl)-2-oxido-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate
Catalogue No.:PA 09 0151007
Molecular Formula : C22H20N2Na2O6
Molecular Weight : 454.39