azacitidine
Azacytidine has been used as an antineoplastic agent.A pyrimidine nucleoside analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Reference standards of Azacitidine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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Azacitidine - API Standards
Catalogue No.:PA 28 20000
Molecular Formula : C8H12N4O5
Molecular Weight : 244.20
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((3aR,4R,6R,6aR)-6-(4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate
Catalogue No.:PA 28 0201015
Molecular Formula : C16H23N3O7
Molecular Weight : 369.37
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N-(Formylamidino)-N'-beta-D-ribofuranosylurea
Catalogue No.:PA 28 20510
Molecular Formula : C8H14N4O6
Molecular Weight : 262.22
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1-β-D-Ribofuranosyl-3-aminocarbonyl Guandinine
Catalogue No.:PA 28 20630
Molecular Formula : C7H14N4O5
Molecular Weight : 234.21
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1-β-D-Ribofuranosyl-3-iminohydroxymethyl Guandinine
Catalogue No.:PA 28 20640
Molecular Formula : C7H14N4O5
Molecular Weight : 234.21
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N-((Diaminomethylene)carbamoyl)-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)formamide
Catalogue No.:PA 28 20650
Molecular Formula : C8H14N4O6
Molecular Weight : 262.22
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N-((Z)-N'-(((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)carbamoyl)carbamimidoyl)formamide
Catalogue No.:PA 28 20660
Molecular Formula : C8H14N4O6
Molecular Weight : 262.22
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N-ForMyl-D-ribofuranosyl-3-guanylurea (α/β-Mixture)
Catalogue No.:PA 28 20670
Molecular Formula : C8H14N4O6
Molecular Weight : 262.22
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6-Methyl-5-(methylamino)-2H-1,2,4-triazin-3-one
Catalogue No.:PA 28 20690
Molecular Formula : C5H8N4O
Molecular Weight : 140.15
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3-(Dimethylamino)-1,2,4-triazin-5(2H)-one
Catalogue No.:PA 28 20700
Molecular Formula : C5H8N4O
Molecular Weight : 140.15
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-bromotetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 20710
Molecular Formula : C11H15BrO7
Molecular Weight : 339.14
stdClass Object
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[catalogue_number] => PA 28 20720
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[weight] => 376.32
[form] => C13H20N4O9
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4-Amino-1-((2R,3R,4R,5R)-3-(((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
Catalogue No.:PA 28 20720
Molecular Formula : C13H20N4O9
Molecular Weight : 376.32
stdClass Object
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[pname] => 2'-O-Acetyl-5-azacytidine
[catalogue_number] => PA 28 20730
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[form] => C10H14N4O6
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2'-O-Acetyl-5-azacytidine
Catalogue No.:PA 28 20730
Molecular Formula : C10H14N4O6
Molecular Weight : 286.24
stdClass Object
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-hydroxytetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 0201000
Molecular Formula : C11H16O8
Molecular Weight : 276.24
stdClass Object
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[catalogue_number] => PA 28 0201001
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1,2,3,5-Tetra-O-acetyl-β-L-xylofuranose
Catalogue No.:PA 28 0201001
Molecular Formula : C13H18O9
Molecular Weight : 318.28
stdClass Object
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β-D-Xylofuranose-1,2,3,5-tetraacetate
Catalogue No.:PA 28 0201002
Molecular Formula : C13H18O9
Molecular Weight : 318.28
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1,2,3,5-Tetra-O-acetyl β-L-Ribofuranose
Catalogue No.:PA 28 0201003
Molecular Formula : C13H18O9
Molecular Weight : 318.28
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1,2,3,5-Tetra-O-acetyl-α-L-arabinofuranose
Catalogue No.:PA 28 0201004
Molecular Formula : C13H18O9
Molecular Weight : 318.28
stdClass Object
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α-D-Arabinofuranose-1,2,3,5-tetraacetate
Catalogue No.:PA 28 0201005
Molecular Formula : C13H18O9
Molecular Weight : 318.28
stdClass Object
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α-D-Lyxofuranose-1,2,3,5-tetraacetate
Catalogue No.:PA 28 0201006
Molecular Formula : C13H18O9
Molecular Weight : 318.28
stdClass Object
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[weight] => 259.22
[form] => C8H13N5O5
[cas] => 105331-00-8
[pslug] => 105331-00-8-6-amino-5-azacytidine-pa280201007
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Catalogue No.:PA 28 0201007
Molecular Formula : C8H13N5O5
Molecular Weight : 259.22
stdClass Object
(
[pname] => N-[(Methylamino)(methylimino)methyl]- Urea
[catalogue_number] => PA 28 0201008
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 130.15
[form] => C4H10N4O
[cas] => 1314977-44-0
[pslug] => 1314977-44-0-n-methylamino-methylimino-methyl-urea-pa280201008
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N-[(Methylamino)(methylimino)methyl]- Urea
Catalogue No.:PA 28 0201008
Molecular Formula : C4H10N4O
Molecular Weight : 130.15
stdClass Object
(
[pname] => 4-Amino-6-hydroxy-5,6-dihydro-1,3,5-triazin-2(1H)-one
[catalogue_number] => PA 28 0201009
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 130.11
[form] => C3H6N4O2
[cas] => 915106-20-6
[pslug] => 915106-20-6-4-amino-6-hydroxy-5-6-dihydro-1-3-5-triazin-2-1h-one-pa280201009
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4-Amino-6-hydroxy-5,6-dihydro-1,3,5-triazin-2(1H)-one
Catalogue No.:PA 28 0201009
Molecular Formula : C3H6N4O2
Molecular Weight : 130.11
stdClass Object
(
[pname] => ((Z)-Amino(((Z)-aminomethylene)amino)methylene)carbamic Acid
[catalogue_number] => PA 28 0201010
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 130.11
[form] => C3H6N4O2
[cas] => NA
[pslug] => z-amino-z-aminomethylene-amino-methylene-carbamic-acid-pa280201010
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((Z)-Amino(((Z)-aminomethylene)amino)methylene)carbamic Acid
Catalogue No.:PA 28 0201010
Molecular Formula : C3H6N4O2
Molecular Weight : 130.11
stdClass Object
(
[pname] => Cytidine 5’-Monophosphate Methyl Ester
[catalogue_number] => PA 28 0201011
[category_ids] => 82,78,76,75,70
[chemical_name] =>
[weight] => 337.22
[form] => C10H16N3O8P
[cas] => 52448-10-9
[pslug] => 52448-10-9-cytidine-5-monophosphate-methyl-ester-pa280201011
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Cytidine 5’-Monophosphate Methyl Ester
Catalogue No.:PA 28 0201011
Molecular Formula : C10H16N3O8P
Molecular Weight : 337.22
stdClass Object
(
[pname] => Azacitidine diphosphate
[catalogue_number] => PA 28 0201012
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 404.16
[form] => C8H14N4O11P2
[cas] => NA
[pslug] => azacitidine-diphosphate-pa280201012
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Catalogue No.:PA 28 0201012
Molecular Formula : C8H14N4O11P2
Molecular Weight : 404.16
stdClass Object
(
[pname] => 1-(2,2-Diaminovinylidene)-3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)urea
[catalogue_number] => PA 28 0201013
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 246.22
[form] => C8H14N4O5
[cas] => NA
[pslug] => 1-2-2-diaminovinylidene-3-2r-3r-4s-5r-3-4-dihydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-urea-pa280201013
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1-(2,2-Diaminovinylidene)-3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)urea
Catalogue No.:PA 28 0201013
Molecular Formula : C8H14N4O5
Molecular Weight : 246.22
stdClass Object
(
[pname] => 4-Amino-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidin-2(1H)-one sulfate
[catalogue_number] => PA 28 0201014
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 381.36
[form] => C12H19N3O9S
[cas] => 1955522-00-5
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4-Amino-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidin-2(1H)-one sulfate
Catalogue No.:PA 28 0201014
Molecular Formula : C12H19N3O9S
Molecular Weight : 381.36
stdClass Object
(
[pname] => 2',3',5'-Tri-O-Benzoyl-5-Azacytidine
[catalogue_number] => PA 28 0201016
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 556.53
[form] => C29H24N4O8
[cas] => 28998-36-9
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2',3',5'-Tri-O-Benzoyl-5-Azacytidine
Catalogue No.:PA 28 0201016
Molecular Formula : C29H24N4O8
Molecular Weight : 556.53
stdClass Object
(
[pname] => (3aS,5R,6R,6aR)-6-Hydroxy-5-(hydroxymethyl)tetrahydrofuro[2,3-d]oxazol-2(3H)-one
[catalogue_number] => PA 28 0201017
[category_ids] => ,75,76,78,70,82,
[chemical_name] =>
[weight] => 175.14
[form] => C6H9NO5
[cas] => 2508-81-8
[pslug] => 2508-81-8-3as-5r-6r-6ar-6-hydroxy-5-hydroxymethyl-tetrahydrofuro-2-3-d-oxazol-2-3h-one-pa280201017
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(3aS,5R,6R,6aR)-6-Hydroxy-5-(hydroxymethyl)tetrahydrofuro[2,3-d]oxazol-2(3H)-one
Catalogue No.:PA 28 0201017
Molecular Formula : C6H9NO5
Molecular Weight : 175.14
stdClass Object
(
[pname] => 1-b-D-Ribofuranosyl-3-aminocarbonyl guanidine Acetate
[catalogue_number] => PA 28 0201018
[category_ids] => 82,78,76,75,70
[chemical_name] =>
[weight] => 294.26
[form] => C9H18N4O7
[cas] => 2775292-15-2
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1-b-D-Ribofuranosyl-3-aminocarbonyl guanidine Acetate
Catalogue No.:PA 28 0201018
Molecular Formula : C9H18N4O7
Molecular Weight : 294.26
stdClass Object
(
[pname] => Azacitidine Formyl Impurity
[catalogue_number] => PA 28 0201019
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[weight] => 162.11
[form] => C3H6N4O4
[cas] => NA
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Azacitidine Formyl Impurity
Catalogue No.:PA 28 0201019
Molecular Formula : C3H6N4O4
Molecular Weight : 162.11
stdClass Object
(
[pname] => beta-D-Ribofuranose, 1-acetate 2,3-dibenzoate
[catalogue_number] => PA 28 0201021
[category_ids] => ,91,85,83,78,70,82,
[chemical_name] =>
[weight] => 400.38
[form] => C21H20O8
[cas] => 114405-77-5
[pslug] => 114405-77-5-beta-d-ribofuranose-1-acetate-2-3-dibenzoate-pa280201021
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beta-D-Ribofuranose, 1-acetate 2,3-dibenzoate
Catalogue No.:PA 28 0201021
Molecular Formula : C21H20O8
Molecular Weight : 400.38
stdClass Object
(
[pname] => beta-D-Ribofuranoside, methyl, 2,3,5-tribenzoate
[catalogue_number] => PA 28 0201020
[category_ids] => ,91,85,83,78,70,82,
[chemical_name] =>
[weight] => 476.48
[form] => C27H24O8
[cas] => 52783-53-6
[pslug] => 52783-53-6-beta-d-ribofuranoside-methyl-2-3-5-tribenzoate-pa280201020
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beta-D-Ribofuranoside, methyl, 2,3,5-tribenzoate
Catalogue No.:PA 28 0201020
Molecular Formula : C27H24O8
Molecular Weight : 476.48
stdClass Object
(
[pname] => (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-((5-((2R,3R,4R,5R)-3,4-diacetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl)-4-oxo-4,5-dihydro-1,3,5-triazin-2-yl)amino)tetrahydrofuran-3,4-diyl Diacetate
[catalogue_number] => PA 28 0201022
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 628.54
[form] => C25H32N4O15
[cas] => 2306050-24-6
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-((5-((2R,3R,4R,5R)-3,4-diacetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl)-4-oxo-4,5-dihydro-1,3,5-triazin-2-yl)amino)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 0201022
Molecular Formula : C25H32N4O15
Molecular Weight : 628.54
stdClass Object
(
[pname] => (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(3-((Z)-amino(formamido)methylene)ureido)tetrahydrofuran-3,4-diyl Diacetate
[catalogue_number] => PA 28 0201023
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 388.33
[form] => C14H20N4O9
[cas] => NA
[pslug] => 2r-3r-4r-5r-2-acetoxymethyl-5-3-z-amino-formamido-methylene-ureido-tetrahydrofuran-3-4-diyl-diacetate-pa280201023
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(3-((Z)-amino(formamido)methylene)ureido)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 0201023
Molecular Formula : C14H20N4O9
Molecular Weight : 388.33
stdClass Object
(
[pname] => (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(3-carbamoylguanidino)tetrahydrofuran-3,4-diyl Diacetate
[catalogue_number] => PA 28 0201024
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 360.32
[form] => C13H20N4O8
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(3-carbamoylguanidino)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 0201024
Molecular Formula : C13H20N4O8
Molecular Weight : 360.32
stdClass Object
(
[pname] => (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(N-(hydroxymethyl)diazenecarboximidamido)tetrahydrofuran-3,4-diyl Diacetate
[catalogue_number] => PA 28 0201025
[category_ids] => ,78,70,82,
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[weight] => 360.32
[form] => C13H20N4O8
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(N-(hydroxymethyl)diazenecarboximidamido)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 0201025
Molecular Formula : C13H20N4O8
Molecular Weight : 360.32
stdClass Object
(
[pname] => (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(3-(diaminomethylene)ureido)tetrahydrofuran-3,4-diyl Diacetate
[catalogue_number] => PA 28 0201026
[category_ids] => ,78,70,82,
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[weight] => 360.32
[form] => C13H20N4O8
[cas] => 10302-77-9
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(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(3-(diaminomethylene)ureido)tetrahydrofuran-3,4-diyl Diacetate
Catalogue No.:PA 28 0201026
Molecular Formula : C13H20N4O8
Molecular Weight : 360.32
stdClass Object
(
[pname] => 4-Amino-1-((2R,3R,4S,5R)-5-((((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
[catalogue_number] => PA 28 0201027
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 376.32
[form] => C13H20N4O9
[cas] => 2415172-81-3
[pslug] => 2415172-81-3-4-amino-1-2r-3r-4s-5r-5-2r-3r-4s-5r-3-4-dihydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-oxy-methyl-3-4-dihydroxytetrahydrofuran-2-yl-1-3-5-triazin-2-1h-one-pa280201027
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4-Amino-1-((2R,3R,4S,5R)-5-((((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
Catalogue No.:PA 28 0201027
Molecular Formula : C13H20N4O9
Molecular Weight : 376.32
stdClass Object
(
[pname] => N-(9-Acetyl-9H-purin-6-yl)acetamide
[catalogue_number] => PA 28 0201028
[category_ids] => ,76,78,70,82,
[chemical_name] =>
[weight] => 219.2
[form] => C9H9N5O2
[cas] => 10527-91-0
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N-(9-Acetyl-9H-purin-6-yl)acetamide
stdClass Object
(
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[catalogue_number] => PA 28 0201029
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[chemical_name] =>
[weight] => 328.28
[form] => C12H16N4O7
[cas] => 1415316-72-1
[pslug] => 1415316-72-1-2r-3r-4r-5r-2-4-amino-2-oxo-1-3-5-triazin-1-2h-yl-5-hydroxymethyl-tetrahydrofuran-3-4-diyl-diacetate-pa280201029
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(2R,3R,4R,5R)-2-(4-Amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate
Catalogue No.:PA 28 0201029
Molecular Formula : C12H16N4O7
Molecular Weight : 328.28
stdClass Object
(
[pname] => (Z)-N'-((2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl)-N-(diaminomethylene)carbamimidic Acid
[catalogue_number] => PA 28 0201030
[category_ids] => ,76,78,70,82,
[chemical_name] =>
[weight] => 360.32
[form] => C13H20N4O8
[cas] => NA
[pslug] => z-n-2r-3r-4r-5r-3-4-diacetoxy-5-acetoxymethyl-tetrahydrofuran-2-yl-n-diaminomethylene-carbamimidic-acid-pa280201030
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(Z)-N'-((2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl)-N-(diaminomethylene)carbamimidic Acid
Catalogue No.:PA 28 0201030
Molecular Formula : C13H20N4O8
Molecular Weight : 360.32
stdClass Object
(
[pname] => N-Formylguanidine
[catalogue_number] => PA 28 0201031
[category_ids] => ,91,85,83,78,70,82,
[chemical_name] =>
[weight] => 87.08
[form] => C2H5N3O
[cas] => 4471-51-6
[pslug] => 4471-51-6-n-formylguanidine-pa280201031
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stdClass Object
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[pname] => 5-Azauridine
[catalogue_number] => PA 28 0201032
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[chemical_name] =>
[weight] => 245.19
[form] => C8H11N3O6
[cas] => 1476-82-0
[pslug] => 1476-82-0-5-azauridine-pa280201032
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Catalogue No.:PA 28 0201032
Molecular Formula : C8H11N3O6
Molecular Weight : 245.19
stdClass Object
(
[pname] => (Z)-2-(Aminoethynyl)-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)hydrazine-1-carbimidic Acid
[catalogue_number] => PA 28 0201033
[category_ids] => ,91,85,83,78,70,82,
[chemical_name] =>
[weight] => 246.22
[form] => C8H14N4O5
[cas] => NA
[pslug] => z-2-aminoethynyl-n-2r-3r-4s-5r-3-4-dihydroxy-5-hydroxymethyl-tetrahydrofuran-2-yl-hydrazine-1-carbimidic-acid-pa280201033
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(Z)-2-(Aminoethynyl)-N-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)hydrazine-1-carbimidic Acid
Catalogue No.:PA 28 0201033
Molecular Formula : C8H14N4O5
Molecular Weight : 246.22