Aprepitant-impurities | Pharmaffiliates

aprepitant and its Impurities

Aprepitant is used to prevent chemotherapy-induced nausea and vomiting and to prevent postoperative nausea and vomiting.. Reference standards of Aprepitant API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 48 results for aprepitant Impurities
PA 28 07000

Aprepitant - API

Aprepitant


  • Catalogue No.:PA 28 07000

  • CAS :

    170729-80-3

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

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PA 28 07010

Aprepitant - Impurity A

Defluoro Aprepitant


  • Catalogue No.:PA 28 07010

  • CAS :

    170729-76-7

  • Molecular Formula : C23H22F6N4O3

  • Molecular Weight : 516.44

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PA 28 07510

Aprepitant N-Oxide

Aprepitant N-Oxide


  • Catalogue No.:PA 28 07510

  • CAS :

    172673-23-3

  • Molecular Formula : C23H21F7N4O4

  • Molecular Weight : 550.43

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PA 28 07520

(R,R,R)-Aprepitant

(R,R,R)-Aprepitant


  • Catalogue No.:PA 28 07520

  • CAS :

    1148113-53-4

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

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PA 28 07550

ent-Aprepitant

ent-Aprepitant


  • Catalogue No.:PA 28 07550

  • CAS :

    172822-29-6

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

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PA 28 07020

Aprepitant - Impurity B

4-Defluoro-3-(p-fluorophenyl) Aprepitant


  • Catalogue No.:PA 28 07020

  • CAS :

    2348441-62-1

  • Molecular Formula : C29H25F7N4O3

  • Molecular Weight : 610.52

PA 28 07030

Aprepitant - Impurity C

4-Defluoro-4-(p-fluorophenyl)aprepitant


  • Catalogue No.:PA 28 07030

  • CAS :

    NA

  • Molecular Formula : C29H25F7N4O3

  • Molecular Weight : 610.52

PA 28 07530

(1R,2S,3S)-Aprepitant

(1R,2S,3S)-Aprepitant


  • Catalogue No.:PA 28 07530

  • CAS :

    172822-28-5

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

PA 28 07540

(1S,2R,3S)-Aprepitant

(1S,2R,3S)-Aprepitant


  • Catalogue No.:PA 28 07540

  • CAS :

    170902-81-5

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

PA 28 07560

(1R,2S,3R)-Aprepitant

(1R,2S,3R)-Aprepitant


  • Catalogue No.:PA 28 07560

  • CAS :

    1185502-97-9

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

PA 28 07570

(1S,2R,3R)-Aprepitant

(1S,2R,3R)-Aprepitant


  • Catalogue No.:PA 28 07570

  • CAS :

    1242175-34-3

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

PA 28 07580

(1S,2S,3S)-Aprepitant

(1S,2S,3S)-Aprepitant


  • Catalogue No.:PA 28 07580

  • CAS :

    1242175-40-1

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

PA 28 07590

Aprepitant M2 Metabolite (1R,2R,3S)-Isomer

Aprepitant M2 Metabolite (1R,2R,3S)-Isomer


  • Catalogue No.:PA 28 07590

  • CAS :

    171338-27-5

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.35

PA 28 07600

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant


  • Catalogue No.:PA 28 07600

  • CAS :

    219821-37-1

  • Molecular Formula : C24H25F7N4O4

  • Molecular Weight : 566.47

PA STI 008250

ent-Aprepitant-13C15N2

ent-Aprepitant-13C15N2


  • Catalogue No.:PA STI 008250

  • CAS :

    2724540-72-9

  • Molecular Formula : C2213CH21F7N215N2O3

  • Molecular Weight : 537.40

PA STI 008260

Aprepitant-13C2,d2 (Major)

Aprepitant-13C2,d2 (Major)


  • Catalogue No.:PA STI 008260

  • CAS :

    1217676-37-3

  • Molecular Formula : C2113C2H19D2F7N4O3

  • Molecular Weight : 538.42

PA STI 008270

Aprepitant-d4

Aprepitant-d4


  • Catalogue No.:PA STI 008270

  • CAS :

    1133387-60-6

  • Molecular Formula : C23H17D4F7N4O3

  • Molecular Weight : 538.45

PA STI 014030

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenyl-4-[(2-N- methoxycarbonyl)acetamidrazono]morpholine-13C2,d2

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenyl-4-[(2-N- methoxycarbonyl)acetamidrazono]morpholine-13C2,d2


  • Catalogue No.:PA STI 014030

  • CAS :

    NA

  • Molecular Formula : C2213C2H23D2F7N4O4

  • Molecular Weight : 570.47

PA STI 014040

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2 [Aprepitant-M2-d2]

2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2 [Aprepitant-M2-d2]


  • Catalogue No.:PA STI 014040

  • CAS :

    1217645-68-5

  • Molecular Formula : C20H16D2F7NO2

  • Molecular Weight : 439.36

PA STI 014050

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine-d2


  • Catalogue No.:PA STI 014050

  • CAS :

    1217725-13-7

  • Molecular Formula : C20H16D2F7NO2

  • Molecular Weight : 439.36

PA USP1041915

Aprepitant Related Compound A (3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041915)

Aprepitant Related Compound A (3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041915)


  • Catalogue No.:PA USP1041915

  • CAS :

    1148113-53-4

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1041992

Desfluoro Aprepitant (5-{[(2R,3S)-2-{(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenylmorpholi (1041992)

Desfluoro Aprepitant (5-{[(2R,3S)-2-{(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenylmorpholi (1041992)


  • Catalogue No.:PA USP1041992

  • CAS :

    170729-76-7

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1041904

Aprepitant (1041904)

Aprepitant (1041904)


  • Catalogue No.:PA USP1041904

  • CAS :

    170729-80-3

  • Molecular Formula : NA

  • Molecular Weight : NA

PA USP1041926

Aprepitant Related Compound B (3-[[(2S,3R)-2-[(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041926)

Aprepitant Related Compound B (3-[[(2S,3R)-2-[(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fl (1041926)


  • Catalogue No.:PA USP1041926

  • CAS :

    172822-29-6

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0001825

Aprepitant (Y0001825)

Aprepitant (Y0001825)


  • Catalogue No.:PA EPY0001825

  • CAS :

    170729-80-3

  • Molecular Formula : NA

  • Molecular Weight : NA

PA EPY0001826

Aprepitant for system suitability (Y0001826)

Aprepitant for system suitability (Y0001826)


  • Catalogue No.:PA EPY0001826

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

PA 28 07610

(2R,3S)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine Oxalate

(2R,3S)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine Oxalate


  • Catalogue No.:PA 28 07610

  • CAS :

    NA

  • Molecular Formula : C22H20F7NO6

  • Molecular Weight : 527.39

PA 28 0071000

N-Methylcarbonyl-2-chloroacetamidrazone

N-Methylcarbonyl-2-chloroacetamidrazone


  • Catalogue No.:PA 28 0071000

  • CAS :

    155742-64-6

  • Molecular Formula : C4H8ClN3O2

  • Molecular Weight : 165.58

PA 28 0071004

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate


  • Catalogue No.:PA 28 0071004

  • CAS :

    200000-59-5

  • Molecular Formula : C27H26F7NO5S

  • Molecular Weight : 609.56

PA 28 0071001

Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer

Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer


  • Catalogue No.:PA 28 0071001

  • CAS :

    170902-80-4

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071002

(5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone

Aprepitant M3 Metabolite (1R, 5R, 6R)-Isomer


  • Catalogue No.:PA 28 0071002

  • CAS :

    419574-33-7

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071003

Aprepitant M3 Metabolite (1R, 5S, 6R)-Isomer

Aprepitant M3 Metabolite (1R, 5S, 6R)-Isomer


  • Catalogue No.:PA 28 0071003

  • CAS :

    419574-04-2

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071005

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-aprepitant

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'R)-aprepitant


  • Catalogue No.:PA 28 0071005

  • CAS :

    1185503-48-3

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071006

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride


  • Catalogue No.:PA 28 0071006

  • CAS :

    171482-05-6

  • Molecular Formula : C20H19ClF7NO2

  • Molecular Weight : 473.82

PA 28 0071007

Aprepitant M2 metabolite (1R, 2R, 3R)-isomer

Aprepitant M2 metabolite (1R, 2R, 3R)-isomer


  • Catalogue No.:PA 28 0071007

  • CAS :

    380499-06-9

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071008

(2R,3R)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine

(2R,3R)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine


  • Catalogue No.:PA 28 0071008

  • CAS :

    1242175-36-5

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071009

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine

2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine


  • Catalogue No.:PA 28 0071009

  • CAS :

    170729-79-0

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071010

(2S,3S)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine

(2S,3S)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine


  • Catalogue No.:PA 28 0071010

  • CAS :

    1242175-38-7

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071011

(5R,6S)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one

(5R,6S)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one


  • Catalogue No.:PA 28 0071011

  • CAS :

    NA

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071012

(5S,6S)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one

(5S,6S)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one


  • Catalogue No.:PA 28 0071012

  • CAS :

    NA

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071013

(5R,6R)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone

(5R,6R)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone


  • Catalogue No.:PA 28 0071013

  • CAS :

    NA

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071014

(5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone

(5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone


  • Catalogue No.:PA 28 0071014

  • CAS :

    NA

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071015

(5S,6R)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone

(5S,6R)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone


  • Catalogue No.:PA 28 0071015

  • CAS :

    NA

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071016

(5S,6S)-6-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one

(5S,6S)-6-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)morpholin-3-one


  • Catalogue No.:PA 28 0071016

  • CAS :

    NA

  • Molecular Formula : C20H16F7NO3

  • Molecular Weight : 451.34

PA 28 0071017

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-aprepitant

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-aprepitant


  • Catalogue No.:PA 28 0071017

  • CAS :

    327623-37-0

  • Molecular Formula : C20H18F7NO2

  • Molecular Weight : 437.36

PA 28 0071018

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine


  • Catalogue No.:PA 28 0071018

  • CAS :

    171338-33-3

  • Molecular Formula : C20H19F6NO2

  • Molecular Weight : 419.37

PA 28 0071019

2-Chloro-1,3-bis(trifluoromethyl)benzene

2-Chloro-1,3-bis(trifluoromethyl)benzene


  • Catalogue No.:PA 28 0071019

  • CAS :

    63430-02-4

  • Molecular Formula : C8H3ClF6

  • Molecular Weight : 248.55

PA 01 3461000

Aprepitant M2 Metabolite (1R,2R,3R)-Isomer  Hydrochloride

Aprepitant M2 Metabolite (1R,2R,3R)-Isomer Hydrochloride


  • Catalogue No.:PA 01 3461000

  • CAS :

    1447693-83-5

  • Molecular Formula : C20H19ClF7NO2

  • Molecular Weight : 473.82