Deuterated Solvents- Spotlight products of Pharmaffiliates

Deuterated Solvents- Spotlight products of Pharmaffiliates

Published Sep 10, 2019 by pharmaffiliates
Deuterated Solvents- Spotlight products of Pharmaffiliates

Solvents where one or more hydrogen atoms are substituted with Deuterium atoms are termed as Deuterated Solvents. The major use of these Deuterated Solvents is in 1H-NMR spectroscopy.

There are three main reasons WHY Deuterated Solvents are used in Nuclear Magnetic Resonance Spectroscopy:

Reason A-To avoid swamping by the solvent signal.

Explanation: An ordinary proton-containing solvent gives a huge solvent absorption that would dominate the 1H-NMR spectrum and interfere with the peaks of protons of interest. Most 1H- NMR spectra are therefore recorded in a deuterated solvent, because deuterium atoms absorb at a completely different frequency.

Reason B - To stabilize the magnetic field strength.

Explanation:The field strength of superconducting magnets tends to drift slowly. Modern NMR spectrometers measure the deuterium absorption of the solvent and adjust the field strength to keep the resonance frequency (field strength) constant.

Reason C - To accurately define 0 ppm.

Explanation:The difference between the deuterium frequency and 0 ppm (TMS) is well known and well defined.

To satisfy the most rigorous demands of NMR-based research and analyses, high quality, high purity, and highly enriched deuterated solvents are required.

Deuterated solvent must be meticulously purified and analyzed for the presence of water content and its protonated form so as to obtain a high purified and deuterium enriched solvent.

Pharmaffiliates Analytics and Synthetics Pvt. Ltdis committed to providing a range of NMR solvents for routine use with excellent chemical purity and with the highest isotopic enrichment. Our company works continuously to preserve the quality of the product and to reduce the water content in high-quality NMR solvents.

Pharmaffiliates has introduced deuterated solvents into its catalog and the details are mentioned below:

(1). Chloroform – d (CDCL3) (D, 99.9%)
Catalog Code : PA STI 088040
CAS No- 865-49-6
For more details :

(2). Dimethyl Sulfoxide – D6 (DMSO-D6) (D, 99.9%)
Catalog Code : PA STI 088030
CAS No- 2206-27-1
For more details :

The above-mentioned products are readily available at Pharmaffiliates in our newly introduced category of Deuterated Solvents. Visit our website for more details. Also, login as a registered customer to avail discounts on our catalog codes PA STI 088040 and PA STI 088030

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