Remdesivir – A new “standard of care” against COVID 19

Published Jun 02, 2020 by pharmaffiliates
 A New Standard Of Care Against COVID-19

Fauci, the director of the National Institute of Allergy and Infectious Diseases, announced in an unpublished from a phase 3 trial that showed Remdesivir shortened the time to recovery for patients with COVID-19 from 15 days to 11 days.

He added he believed Gilead Science’s investigational antiviral “will be the standard of care” for the novel disease.

Generally, Remdesivir is a broad-spectrum antiviral drug developed by American biopharmaceutical giant Gilead Sciences.

Remdesivir

Remdesivir

CAS No - 1809249-37-3

Originally, Remdesivir was developed for the treatment of Hepatitis C. Eventually, in the past this drug has been effectively used for the treat SARS coronavirus and MERS coronavirus, and now researchers around the globe are hopeful that this drug stands strong against COVID 19 as well.

Remdesivir works by interfering with the replication of viruses including SARs and CoV 19 which is responsible for the current pandemic. US Food and Drug Administration (FDA) granted an ‘emergency use authorization’ for clinicians to use the drug.

This is a testing times for the medicinal and scientific fraternity from the world and researchers are furiously trying to develop a drug and save the mankind from deadly virus.

Remdesivir is a ray of hope,a standards of care, not a permanent curebut still can have a heavy impact on slowing down the pandemic.

But the current situation worldwide is grim. The global pandemic COVID-19 continues to engulf the worldas the numbers of patients are increasing day by day overloading the hospitals and shattering the global economy.

Pharmaffiliates has developed a series of products in the form of Reference standards, Metabolites, Impurities and Stable Isotopes which might be used as research materials for the treatment of coronavirus.

Product Code Product Name Cas No.
PA 18 1080000 Remdesivir - API 1809249-37-3
PA 18 1081000 (2S,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile 1355049-95-4
PA 18 1081001 (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-((benzyloxy)methyl)-3,4-dihydroxytetrahydrofuran-2-carbonitrile NA
PA 18 1081002 2-Ethylbutyl ((R)-(4-nitrophenoxy)(phenoxy)phosphoryl)-D-alaninate 2093124-22-0
PA 18 1081003 2-Ethylbutyl ((R)-((5-nitrohexa-1,5-dien-2-yl)oxy)(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081004 2-Ethylbutyl ((S)-(((Z)-5-nitrohexa-1,3,5-trien-2-yl)oxy)(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081005 2-Ethylbutyl ((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)-D-alaninate 2096985-18-9
PA 18 1081006 2-Ethylbutyl (chloro(phenoxy)phosphoryl)-L-alaninate 1355049-92-1
PA 18 1081007 2-Ethylbutyl ((R)-hydroxy(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081008 2-Ethylbutyl D-alaninate 1689993-65-4
PA 18 1081009 2-Ethylbutyl ((R)-(((3aR,4R,6R,6aR)-6-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-cyano-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081010 2-Ethylbutyl ((S)-(((2R,3S,4R,5S)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081011 2-Ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate 2093124-26-4
PA 18 1081012 2-Ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate 1911578-75-0
PA 18 1081013 2-Ethylbutyl (hydroxy(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081014 ((S)-(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanine NA
PA 18 1081015 2-Ethylbutyl L-alaninate 946565-74-8
PA 18 1081016 ((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl phenyl hydrogen (R)-phosphate NA

Remdesivir is readily available with Pharmaffiliates for research and quality control purpose.

Pharmaffiliates is an Indian Research Organization with operation in more than 65 countries. We are an ISO 9001, 17025 Guide 34, DSIR and USFDAapproved firm.

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