Pharmaffiliates Scientific Catalog: APIs, Intermediates & Pharmaceutical Impurities

Published Sept 27, 2025 by pharmaffiliates

Pharmaffiliates provides a curated selection of high-purity pharmaceutical intermediates, APIs, and impurity standards, serving researchers, laboratories, and pharmaceutical manufacturers worldwide. Each compound is detailed below with CAS numbers, chemical properties, applications, and regulatory relevance, offering a comprehensive resource for R&D and quality control purposes.

2-Phenylpropanoic Acid (CAS 492-37-5)

• Type: Organic intermediate / pharmaceutical building block
• Molecular Formula: C9H10O2
• Molecular Weight: 150.17 g/mol
• Appearance: White crystalline powder
• Applications:
• Used in the synthesis of active pharmaceutical ingredients (APIs), especially for chiral compounds.
• Supports R&D and process chemistry in pharmaceutical laboratories.
• Suitable for method development and impurity profiling.
• Regulatory Relevance: Can be used in research under ICH, USP, and EP-compliant methods.

2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester (CAS 150058-27-8)

• Type: Pharmaceutical intermediate / reference compound
• Molecular Formula: C10H11N2O3
• Molecular Weight: 203.21 g/mol
• Appearance: Off-white crystalline solid
• Applications:
• Key intermediate in the synthesis of benzimidazole-based APIs.
• Supports analytical method validation and impurity monitoring.
• Used in process development and quality control workflows.
• Regulatory Relevance: Suitable for research under ICH-compliant conditions.

Abiraterone Acetate 5,6-Epoxide (Mixture)

• Type: API derivative / pharmaceutical intermediate
• Molecular Weight: NA (mixture of epoxides)
• Appearance: Off-white to pale yellow powder
• Applications:
• Used in steroidal drug R&D, including prostate cancer research.
• Supports impurity profiling and analytical method development.
• Regulatory Relevance: Suitable for laboratory research and method validation; not intended for direct pharmaceutical use.

Olodaterol Impurity 2 (CAS 56490-94-9)

• Type: API impurity / reference standard
• Molecular Formula: C21H23NO4
• Molecular Weight: 353.41 g/mol
• Appearance: White to off-white crystalline solid
• Applications:
• Supports QC and analytical testing for olodaterol formulations.
• Used in impurity characterization and method validation in pharmaceutical labs.
• Regulatory Relevance: Complies with ICH guidelines for impurity standards.

3',4'-Dichloropropiophenone (CAS 6582-42-9)

• Type: Chemical intermediate / organic compound
• Molecular Formula: C9H7Cl2O
• Molecular Weight: 188.06 g/mol
• Appearance: Yellow crystalline powder
• Applications:
• Intermediate in API synthesis and medicinal chemistry research.
• Supports process validation, chemical synthesis, and impurity tracking.
• Regulatory Relevance: Laboratory research use; follows standard chemical handling protocols.

(R)-2-(4-Butylphenyl)propanoic Acid (CAS 1263078-21-2)

• Type: Chiral pharmaceutical intermediate
• Molecular Formula: C13H18O2
• Molecular Weight: 206.28 g/mol
• Appearance: White crystalline solid
• Applications:
• Used in stereospecific API synthesis and enantiomeric research.
• Supports impurity profiling, stability studies, and process optimization.
• Regulatory Relevance: Suitable for research under ICH and USP standards.

Pyridine Sulfur Trioxide (CAS 26412-87-3)

• Type: Beta-lactam impurity / chemical reagent
• Molecular Formula: C5H5NOS3
• Molecular Weight: 151.17 g/mol
• Appearance: White crystalline powder
• Applications:
• Used in ceftazidime pentahydrate impurity studies.
• Supports analytical testing and method validation in beta-lactam research.
• Regulatory Relevance: Complies with analytical reference standards for research purposes.

Butanol-tert (CAS 75-65-0)

• Type: Organic solvent / chemical intermediate
• Molecular Formula: C4H10O
• Molecular Weight: 74.12 g/mol
• Appearance: Colorless liquid
• Applications:
• Solvent and intermediate in pharmaceutical synthesis and R&D.
• Supports process chemistry and analytical workflows.
• Regulatory Relevance: Suitable for laboratory use under standard chemical safety protocols.

Conclusion

This catalog highlights Pharmaffiliates commitment to providing high-quality pharmaceutical intermediates, APIs, and impurity standards. Each compound is backed by CAS registration, purity details, and defined applications for research, R&D, and regulatory compliance. Researchers and laboratories worldwide rely on these compounds to ensure accuracy, reproducibility, and adherence to ICH, USP, and EMA guidelines.