Specialized Pharmaceutical Compounds: A Scientific Catalog

Published Sept 27, 2025 by pharmaffiliates

Pharmaceutical research depends on high-purity intermediates, impurities, metabolites, and APIs to ensure safety, efficacy, and regulatory compliance. At Pharmaffiliates, we have spent more than two decades supporting global pharma and biotech companies with authentic reference standards and specialty chemicals.

Below is a scientific catalog of selected products from our portfolio, each playing a unique role in advancing research and quality assurance.

2-(2-Aminothiazol-4-yl)-2-oxoacetic Acid (CAS 73150-67-1)

• Type: Impurity / Intermediate / Reference Standard
• Significance: Thiazole derivatives are integral to β-lactam antibiotics and related antibacterial agents. This compound is particularly valuable in studying degradation pathways.
• Application: Supports impurity profiling, stability studies, and method validation in antibiotic development.
• Pharmaffiliates Advantage: Supplied under controlled storage (2–8 °C) with validated COA, ensuring reproducibility in pharmaceutical testing.

1-Bromo-3-chloro-2-iodobenzene (CAS 450412-28-9)

• Type: Halogenated Aromatic Intermediate
• Significance: Tri-halogenated benzenes are versatile scaffolds for building novel molecules in medicinal and material sciences.
• Application: Used in cross-coupling reactions and as a synthetic building block for APIs and fine chemicals.
• Pharmaffiliates Advantage: Offered in research-grade purity, enabling reliable downstream synthesis.

Pranoprofen (CAS 52549-17-4)

• Type: Active Pharmaceutical Ingredient (NSAID)
• Significance: A non-steroidal anti-inflammatory drug formulated for ophthalmic use, minimizing the risks associated with corticosteroids.
• Application: Treats ocular inflammation such as conjunctivitis, blepharitis, and post-surgical irritation. Critical in pharmacokinetic studies and impurity profiling.
• Pharmaffiliates Advantage: Delivered with complete analytical data (COA, NMR, HPLC) to meet ICH Q3 compliance.

4-Chlorobutanoyl Chloride (CAS 4635-59-0)

• Type: Organic Intermediate / Speciality Chemical
• Significance: Acyl chlorides are essential reagents for introducing functional groups in drug synthesis.
• Application: Applied in acylation reactions, synthesis of intermediates, and impurity reference testing.
• Pharmaffiliates Advantage: Produced and stored under strict quality systems to ensure stability and purity.

o-Acetyltoluene (CAS 577-16-2)

• Type: Aromatic Ketone / Impurity Standard
• Significance: Structurally related to intermediates in fragrances and pharmaceuticals, making it valuable for impurity studies.
• Application: Used in organic synthesis and impurity profiling of aromatic compounds.
• Pharmaffiliates Advantage: Supplied in high purity with batch traceability, supporting regulatory documentation.

2,3-Lutidine (CAS 583-61-9)

• Type: Pyridine Derivative / Pharmaceutical Intermediate
• Significance: A dimethyl-substituted pyridine widely used in synthesizing proton-pump inhibitors and related heterocycles.
• Application: Acts as a catalyst base, intermediate, and impurity marker in pharmaceutical research.
• Pharmaffiliates Advantage: Available as both impurity reference and fine chemical to support QC and R&D projects.

6-Bromo-2-naphthoic Acid (CAS 5773-80-8)

• Type: Fine Chemical / Synthetic Intermediate
• Significance: Naphthoic acid derivatives serve as building blocks in dyes, polymers, and pharmaceuticals.
• Application: Useful in organic synthesis and impurity profiling for naphthalene-based molecules.
• Pharmaffiliates Advantage: Backed by ISO 17025-certified analytical labs, ensuring reliable impurity characterization.

DL-Methionine Sulfone (CAS 820-10-0)

• Type: Amino Acid Derivative / Metabolite
• Significance: A key oxidation product of methionine, relevant to nutritional, biochemical, and oxidative stress studies.
• Application: Supports metabolic pathway studies, nutritional testing, and analytical reference validation.
• Pharmaffiliates Advantage: Offered with stability data for accurate use in long-term research projects.

N-Desmethylpheniramine Maleate

• Type: Metabolite / Pharmaceutical Impurity
• Significance: A known metabolite of the antihistamine Pheniramine, used to monitor drug metabolism.
• Application: Applied in impurity profiling, pharmacokinetic studies, and analytical method development.
• Pharmaffiliates Advantage: Manufactured under controlled synthesis conditions, ensuring consistency across research batches.

2-Amino-4-chloropyridine (CAS 19798-80-2)

• Type: Pyridine Derivative / Fine Chemical
• Significance: Chloropyridines are versatile intermediates in the synthesis of APIs and agrochemicals.
• Application: Employed in heterocyclic synthesis, impurity characterization, and stability studies.
• Pharmaffiliates Advantage: Supplied globally with full technical data, supporting both R&D and regulatory filings.

Why These Standards Matter

Each of these compounds strengthens the foundation of drug discovery, impurity profiling, and regulatory compliance. By partnering with Pharmaffiliates, research organizations gain access to:

• High-purity impurities, metabolites, and intermediates
• ISO 17025-certified analytical support
• Custom synthesis and global supply capabilities
• Compliance-ready documentation (COA, MSDS, NMR, HPLC)

At Pharmaffiliates, we remain dedicated to advancing pharmaceutical innovation by delivering trusted scientific solutions worldwide.